Pub. Date : 2000 Nov
PMID : 11071366
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Oxidative inactivation of brain ecto-5"-nucleotidase by thiols/Fe2+ system. | Sulfhydryl Compounds | 5'-nucleotidase | Bos taurus |
| 2 | Overall, thiols, expressing more inhibitory effect on the activity of 5"-nucleotidase, were found to be more effective in potentiating the Fe2+-mediated inactivation. | Sulfhydryl Compounds | 5'-nucleotidase | Bos taurus |
| 3 | Further, kinetic analyses indicate that Fe2+ and thiols inhibit the 5"-nucleotidase in a competitive or uncompetitive manner, respectively. | Sulfhydryl Compounds | 5'-nucleotidase | Bos taurus |
| 4 | These results suggest that ecto-5"-nucleotidase from brain membrane is one of proteins susceptible to thiols/Fe2+-catalyzed oxidation, and the oxidative inactivation may be related to the selective association of Fe2+ and thiols to the enzyme molecule. | Sulfhydryl Compounds | 5'-nucleotidase | Bos taurus |
| 5 | These results suggest that ecto-5"-nucleotidase from brain membrane is one of proteins susceptible to thiols/Fe2+-catalyzed oxidation, and the oxidative inactivation may be related to the selective association of Fe2+ and thiols to the enzyme molecule. | Sulfhydryl Compounds | 5'-nucleotidase | Bos taurus |