Title : Activation of NF-kappaB/Rel occurs early during neoplastic transformation of mammary cells.

Pub. Date : 2000 May

PMID : 10783306






1 Functional Relationships(s)
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1 In S-D rats, increased NF-kappaB/Rel binding was detected in nuclear extracts of mammary glands from 40% of animals 3 weeks post-treatment with 15 mg/kg 7,12-dimethylbenz[a]anthracene (DMBA); this is prior to formation of tumors which normally begin to be detected after 7-9 weeks. 7,12-dimethylbenz nuclear factor kappa B subunit 1 Homo sapiens