Title : Fluvoxamine-Clozapine drug interaction: inhibition in vitro of five cytochrome P450 isoforms involved in clozapine metabolism.

Pub. Date : 2000 Feb

PMID : 10653206






3 Functional Relationships(s)
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1 Fluvoxamine-Clozapine drug interaction: inhibition in vitro of five cytochrome P450 isoforms involved in clozapine metabolism. Fluvoxamine cytochrome P450 family 4 subfamily F member 3 Homo sapiens
2 Fluvoxamine also inhibited in a concentration-dependent manner the activity of all five cytochrome P450 (CYP) isoforms previously determined to be capable of catalyzing the demethylation of clozapine. Fluvoxamine cytochrome P450 family 4 subfamily F member 3 Homo sapiens
3 Fluvoxamine also inhibited in a concentration-dependent manner the activity of all five cytochrome P450 (CYP) isoforms previously determined to be capable of catalyzing the demethylation of clozapine. Fluvoxamine cytochrome P450 family 4 subfamily F member 3 Homo sapiens