Title : Biological properties of human prolactin analogs depend not only on global hormone affinity, but also on the relative affinities of both receptor binding sites.

Pub. Date : 1999 Sep 10

PMID : 10473550






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Zinc increases the affinity of human growth hormone (hGH) for the human prolactin receptor (hPRLR) due to the coordination of one zinc ion involving Glu-174(hGH) and His-18(hGH). Histidine growth hormone 1 Homo sapiens