Title : Effect of an aluminum hydroxide-magnesium hydroxide combination drug on adhesion, IL-8 inducibility, and expression of HSP60 by Helicobacter pylori.

Pub. Date : 1999 Jul

PMID : 10466876






3 Functional Relationships(s)
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1 Extracellular expression of HSP60 on the surface of H. pylori was decreased after treatment with comagaldrox, whereas the intracellular synthesis of HSP60 was not. aluminum hydroxide, magnesium hydroxide, drug combination heat shock protein family D (Hsp60) member 1 Homo sapiens
2 HSP60-induced IL-8 secretion was significantly inhibited by co-magaldrox in a dose-dependent manner. aluminum hydroxide, magnesium hydroxide, drug combination heat shock protein family D (Hsp60) member 1 Homo sapiens
3 CONCLUSIONS: These results show that co-magaldrox suppressed the expression of the following virulence factors: adhesion, IL-8 inducibility, and expression of extracellular HSP60. aluminum hydroxide, magnesium hydroxide, drug combination heat shock protein family D (Hsp60) member 1 Homo sapiens