Title : P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.

Pub. Date : 1999 Sep 1

PMID : 10462436






1 Functional Relationships(s)
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1 Two other nuclear receptors, designated LXR and FXR, which are respectively activated by oxysterols and bile acids, also play a role in liver P450 expression, in this case regulation of P450 cholesterol 7alpha-hydroxylase, a key enzyme of bile acid biosynthesis. Oxysterols nuclear receptor subfamily 1 group H member 4 Homo sapiens