Title : Egr-1 is a downstream effector of GnRH and synergizes by direct interaction with Ptx1 and SF-1 to enhance luteinizing hormone beta gene transcription.

Pub. Date : 1999 Apr

PMID : 10082522






1 Functional Relationships(s)
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1 GnRH stimulation of gonadotropin expression and secretion occurs through the G-protein-linked phospholipase C/inositol triphosphate intracellular signaling pathway, which ultimately leads to protein kinase C (PKC) activation and increased intracellular calcium levels. Inositol triphosphate gonadotropin releasing hormone 1 Homo sapiens