Title : Endogenous platelet-activating factor is critically involved in effector functions of eosinophils stimulated with IL-5 or IgG.

Pub. Date : 1999 Mar 1

PMID : 10072549






3 Functional Relationships(s)
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1 Human eosinophils produced superoxide when stimulated with immobilized IgG, soluble IL-5, or PAF. Superoxides PCNA clamp associated factor Homo sapiens
2 Furthermore, structurally distinct PAF antagonists, including CV6209, hexanolamine PAF, and Y-24180 (israpafant), inhibited IgG- or IL-5-induced superoxide production and degranulation. Superoxides PCNA clamp associated factor Homo sapiens
3 Furthermore, structurally distinct PAF antagonists, including CV6209, hexanolamine PAF, and Y-24180 (israpafant), inhibited IgG- or IL-5-induced superoxide production and degranulation. Superoxides PCNA clamp associated factor Homo sapiens