Hydrogen Peroxide

apurinic/apyrimidinic endodeoxyribonuclease 1 ; Homo sapiens







32 Article(s)
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1 33410354 Feedback of hypoxia-inducible factor-1alpha (HIF-1alpha) transcriptional activity via redox factor-1 (Ref-1) induction by reactive oxygen species (ROS). 2021 Feb 1
2 33679014 Hydrogen peroxide regulates antioxidant responses and redox related proteins in drought stressed wheat seedlings. 2021 Jan 1
3 32627281 Excess hydrogen peroxide inhibits head and foot regeneration in hydra by affecting DNA repair and expression of essential genes. 2020 Nov 1
4 33065487 Hydrogen peroxide and Helicobacter pylori extract treatment combined with APE1 knockdown induce DNA damage, G2/M arrest and cell death in gastric cancer cell line. 2020 Dec 3
5 29230937 Chrysanthemum CmHSFA4 gene positively regulates salt stress tolerance in transgenic chrysanthemum. 2018 Jul 1
6 26081414 Ape1 regulates WNT/β-catenin signaling through its redox functional domain in pancreatic cancer cells. 2015 Aug 1
7 26268226 Bcl2 inhibition of mitochondrial DNA repair. 2015 Aug 13 2
8 26271980 [Protective effect of Astragalus polysaccharide on MRC-5 cells from oxidative damage induced by hydrogen peroxide]. 2015 Aug 2
9 23369758 Genetic variants of the APE1 gene and the risk of vitiligo in a Chinese population: a genotype-phenotype correlation study. 2013 May 1
10 22148505 Characterization of the redox activity and disulfide bond formation in apurinic/apyrimidinic endonuclease. 2012 Jan 17 2
11 22709585 Mitochondrial DNA damage is associated with reduced mitochondrial bioenergetics in Huntington's disease. 2012 Oct 1 1
12 22841870 Nuclear depletion of apurinic/apyrimidinic endonuclease 1 (Ape1/Ref-1) is an indicator of energy disruption in neurons. 2012 Nov 1 1
13 22877972 Phenols of virgin olive oil protects nuclear DNA against oxidative damage in HeLa cells. 2012 Oct 1
14 20185827 Transcriptional regulation of the base excision repair pathway by BRCA1. 2010 Jun 18 2
15 19567405 Direct and indirect roles of RECQL4 in modulating base excision repair capacity. 2009 Sep 15 1
16 20054488 Overexpression of Ref-1 Inhibits Lead-induced Endothelial Cell Death via the Upregulation of Catalase. 2009 Dec 1
17 18061304 Alteration of APE1/ref-1 expression in non-small cell lung cancer: the implications of impaired extracellular superoxide dismutase and catalase antioxidant systems. 2008 May 4
18 18324520 APE1/Ref-1 regulates PTEN expression mediated by Egr-1. 2008 Jan 1
19 19060414 Silencing of Ref-1 expression by retrovirus-mediated shRNA sensitizes HEK293 cells to hydrogen peroxide-induced apoptosis. 2008 Dec 2
20 17443679 Altered intracellular redox status in Gaucher disease fibroblasts and impairment of adaptive response against oxidative stress. 2007 Jul 2
21 17566060 Redox effector factor-1, combined with reactive oxygen species, plays an important role in the transformation of JB6 cells. 2007 Nov 2
22 16399009 Decline in ascorbate peroxidase activity--a prerequisite factor for tepal senescence in gladiolus. 2006 Feb 1
23 16730871 The human apurinic/apyrimidinic endonuclease-1 suppresses activation of poly(adp-ribose) polymerase-1 induced by DNA single strand breaks. 2006 Jul 5 1
24 15661660 The multifunctional DNA repair/redox enzyme Ape1/Ref-1 promotes survival of neurons after oxidative stress. 2005 Mar 2 5
25 16077024 Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP. 2005 2
26 16373707 Alterations in the expression of the apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE/Ref-1) in human melanoma and identification of the therapeutic potential of resveratrol as an APE/Ref-1 inhibitor. 2005 Dec 1
27 15362040 Helicobacter pylori and H2O2 increase AP endonuclease-1/redox factor-1 expression in human gastric epithelial cells. 2004 Sep 1
28 12384995 H(2)O(2) induces translocation of APE/Ref-1 to mitochondria in the Raji B-cell line. 2002 Nov 2
29 10666449 An 'environment to nucleus' signaling system operates in B lymphocytes: redox status modulates BSAP/Pax-5 activation through Ref-1 nuclear translocation. 2000 Mar 1 1
30 10441516 Transcriptional activation of apurinic/apyrimidinic endonuclease (Ape, Ref-1) by oxidative stress requires CREB. 1999 Aug 11 1
31 9766671 Apurinic endonuclease (Ref-1) is induced in mammalian cells by oxidative stress and involved in clastogenic adaptation. 1998 Oct 1 1
32 8592168 Relationship between expression of a major apurinic/apyrimidinic endonuclease (APEX nuclease) and susceptibility to genotoxic agents in human glioma cell lines. 1995 1