| 1 |
35338148 | Comprehensive characterization of PTEN mutational profile in a series of 34,129 colorectal cancers. | 2022 Mar 25 |
1 |
| 2 |
34113810 | The mechanism of full activation of tumor suppressor PTEN at the phosphoinositide-enriched membrane. | 2021 May 21 |
1 |
| 3 |
31570378 | PTEN in Hereditary and Sporadic Cancer. | 2020 Apr 1 |
1 |
| 4 |
31818848 | PTEN: Bridging Endocytosis and Signaling. | 2020 Oct 1 |
1 |
| 5 |
31932465 | Discovery of the PTEN Tumor Suppressor and Its Connection to the PI3K and AKT Oncogenes. | 2020 Aug 3 |
1 |
| 6 |
31947601 | Crosstalk between PTEN/PI3K/Akt Signalling and DNA Damage in the Oocyte: Implications for Primordial Follicle Activation, Oocyte Quality and Ageing. | 2020 Jan 14 |
1 |
| 7 |
32111929 | Single-molecule imaging of PI(4,5)P2 and PTEN in vitro reveals a positive feedback mechanism for PTEN membrane binding. | 2020 Feb 28 |
1 |
| 8 |
32319540 | Sevoflurane inhibits the proliferation and invasion of hepatocellular carcinoma cells through regulating the PTEN/Akt/GSK‑3β/β‑catenin signaling pathway by downregulating miR‑25‑3p. | 2020 Jul |
2 |
| 9 |
30201631 | Signaling through non-membrane nuclear phosphoinositide binding proteins in human health and disease. | 2019 Feb |
2 |
| 10 |
30735452 | lncRNA GAS5 restrains CCl4-induced hepatic fibrosis by targeting miR-23a through the PTEN/PI3K/Akt signaling pathway. | 2019 Apr 1 |
1 |
| 11 |
31546901 | Prognostic and Predictive Implications of PTEN in Breast Cancer: Unfulfilled Promises but Intriguing Perspectives. | 2019 Sep 19 |
1 |
| 12 |
30623366 | Targeting PTEN in Colorectal Cancers. | 2018 |
1 |
| 13 |
27376697 | Defective phosphoinositide metabolism in autism. | 2017 May |
1 |
| 14 |
27517839 | PTEN loss is associated with a poor response to trastuzumab in HER2-overexpressing gastroesophageal adenocarcinoma. | 2017 May |
1 |
| 15 |
25502460 | Chromosomal Instability and Phosphoinositide Pathway Gene Signatures in Glioblastoma Multiforme. | 2016 Jan |
1 |
| 16 |
25797573 | PTEN Methylation Dependent Sinonasal Mucosal Melanoma. | 2016 Apr |
1 |
| 17 |
25427907 | Understanding the tumor suppressor PTEN in chronic alcoholism and hepatocellular carcinoma. | 2015 |
1 |
| 18 |
25429968 | Phospholipid-binding sites of phosphatase and tensin homolog (PTEN): exploring the mechanism of phosphatidylinositol 4,5-bisphosphate activation. | 2015 Jan 16 |
2 |
| 19 |
25697761 | Biophysical methods for the characterization of PTEN/lipid bilayer interactions. | 2015 May |
1 |
| 20 |
25736313 | Inositol polyphosphate 4-phosphatase II (INPP4B) is associated with chemoresistance and poor outcome in AML. | 2015 Apr 30 |
1 |
| 21 |
25873899 | A method to control phosphoinositides and to analyze PTEN function in living cells using voltage sensitive phosphatases. | 2015 |
1 |
| 22 |
25883023 | INPP4B Is a PtdIns(3,4,5)P3 Phosphatase That Can Act as a Tumor Suppressor. | 2015 Jul |
1 |
| 23 |
25925379 | Dysregulation of AKT Pathway by SMYD2-Mediated Lysine Methylation on PTEN. | 2015 Apr |
1 |
| 24 |
26152921 | INPP4B Is a Tumor Suppressor in the Context of PTEN Deficiency. | 2015 Jul |
1 |
| 25 |
26339505 | Phosphatase and Tensin Homologue: Novel Regulation by Developmental Signaling. | 2015 |
2 |
| 26 |
26504226 | Discovery and functional characterization of a neomorphic PTEN mutation. | 2015 Nov 10 |
2 |
| 27 |
24556334 | Cholesterol stabilizes fluid phosphoinositide domains. | 2014 Sep |
1 |
| 28 |
24475377 | Functions and Regulation of the PTEN Gene in Colorectal Cancer. | 2013 |
1 |
| 29 |
22021906 | Regulation of Cdk7 activity through a phosphatidylinositol (3)-kinase/PKC-ι-mediated signaling cascade in glioblastoma. | 2012 Jan |
1 |
| 30 |
22249254 | Loss of SHIP-1 protein expression in high-risk myelodysplastic syndromes is associated with miR-210 and miR-155. | 2012 Sep 13 |
1 |
| 31 |
22358332 | PI3K signalling: the path to discovery and understanding. | 2012 Feb 23 |
1 |
| 32 |
22403079 | The PTEN and Myotubularin phosphoinositide 3-phosphatases: linking lipid signalling to human disease. | 2012 |
1 |
| 33 |
22413754 | Functional analysis of the protein phosphatase activity of PTEN. | 2012 Jun 15 |
1 |
| 34 |
20214616 | The PKB/AKT pathway in cancer. | 2010 Jan |
1 |
| 35 |
20388916 | Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation. | 2010 Apr 13 |
1 |
| 36 |
20414202 | Phosphoinositide signalling in cancer: beyond PI3K and PTEN. | 2010 May |
1 |
| 37 |
20736378 | Loss of PTEN binding adapter protein NHERF1 from plasma membrane in glioblastoma contributes to PTEN inactivation. | 2010 Sep 1 |
1 |
| 38 |
18996641 | Phosphatase activity of nuclear PTEN is required for CDX2-mediated intestinal differentiation of gastric carcinoma. | 2009 Feb 8 |
1 |
| 39 |
19047050 | Human T-cell leukemia virus type I tax down-regulates the expression of phosphatidylinositol 3,4,5-trisphosphate inositol phosphatases via the NF-kappaB pathway. | 2009 Jan 30 |
1 |
| 40 |
19160672 | Measurement of PTEN activity in vivo by imaging phosphorylated Akt. | 2009 |
1 |
| 41 |
19208634 | Leptin-dependent phosphorylation of PTEN mediates actin restructuring and activation of ATP-sensitive K+ channels. | 2009 Apr 3 |
1 |
| 42 |
19275676 | Role of resistin in insulin sensitivity in rodents and humans. | 2009 Feb |
1 |
| 43 |
19380252 | The PI3K-PTEN tug-of-war, oxidative stress and retinal degeneration. | 2009 May |
1 |
| 44 |
19729658 | Activation of the PI3K pathway in cancer through inhibition of PTEN by exchange factor P-REX2a. | 2009 Sep 4 |
1 |
| 45 |
18220422 | PTEN phosphatase selectively binds phosphoinositides and undergoes structural changes. | 2008 Feb 19 |
1 |
| 46 |
18473732 | The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications. | 2008 May |
1 |
| 47 |
17233581 | Substrate specificity and acute regulation of the tumour suppressor phosphatase, PTEN. | 2007 |
2 |
| 48 |
17254974 | PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42. | 2007 Jan 26 |
1 |
| 49 |
17371253 | Inhibiting PTEN. | 2007 Apr |
1 |
| 50 |
17541013 | Akt-mediated activation of HIF-1 in pulmonary vascular endothelial cells by S-nitrosoglutathione. | 2007 Sep |
1 |