olaparib

phosphatase and tensin homolog ; Homo sapiens







11 Article(s)
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1 33970096 Rapid Response of a BRCA2/TP53/PTEN-Deleted Metastatic Uterine Leiomyosarcoma to Olaparib: A Case Report. 2021 May 1
2 31714594 Poly(adenosine diphosphate ribose) polymerase inhibitors induce autophagy-mediated drug resistance in ovarian cancer cells, xenografts, and patient-derived xenograft models. 2020 Feb 15 1
3 33138032 RAD51-Mediated DNA Homologous Recombination Is Independent of PTEN Mutational Status. 2020 Oct 29 1
4 29500400 Loss of PTEN-assisted G2/M checkpoint impedes homologous recombination repair and enhances radio-curability and PARP inhibitor treatment response in prostate cancer. 2018 Mar 2 1
5 28759753 Inhibition of Rad51 sensitizes breast cancer cells with wild-type PTEN to olaparib. 2017 Oct 7
6 25888415 Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), enhances anti-tumor effects of the poly (ADP-ribose) polymerase (PARP) inhibitor olaparib in triple-negative breast cancer cells. 2015 Mar 7 2
7 24625059 Anti-tumor activity of olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, in cultured endometrial carcinoma cells. 2014 Mar 13 1
8 24675890 Doxorubicin enhances Snail/LSD1-mediated PTEN suppression in a PARP1-dependent manner. 2014 1
9 23239809 Synergistic effect of olaparib with combination of cisplatin on PTEN-deficient lung cancer cells. 2013 Feb 1
10 24222661 Low levels of circulating estrogen sensitize PTEN-null endometrial tumors to PARP inhibition in vivo. 2013 Dec 1
11 20049732 Converting cancer mutations into therapeutic opportunities. 2009 Sep 2