| 1 |
34902358 | Maf1 regulates axonal regeneration of retinal ganglion cells after injury. | 2022 Feb |
1 |
| 2 |
33141044 | Effects of rapamycin and AZD3463 combination on apoptosis, autophagy, and cell cycle for resistance control in breast cancer. | 2021 Jan 1 |
1 |
| 3 |
33532886 | Treatment of Immune Dysregulation Due to a PTEN Variant with Sirolimus. | 2021 Jul |
1 |
| 4 |
33910008 | 4E-BP2-dependent translation in cerebellar Purkinje cells controls spatial memory but not autism-like behaviors. | 2021 Apr 27 |
2 |
| 5 |
34003330 | LKB1-PTEN axis controls Th1 and Th17 cell differentiation via regulating mTORC1. | 2021 Aug |
1 |
| 6 |
31807781 | Resection of a Symptomatic Dysplastic Cerebellar Gangliocytoma: 2-Dimensional Operative Video. | 2020 Aug 1 |
1 |
| 7 |
31896113 | Immunohistochemical Analysis of mTOR Pathway-Related Proteins in Kaposiform Hemangioendothelioma. | 2020 |
1 |
| 8 |
32062191 | Rapamycin inhibits B-cell activating factor (BAFF)-stimulated cell proliferation and survival by suppressing Ca2+-CaMKII-dependent PTEN/Akt-Erk1/2 signaling pathway in normal and neoplastic B-lymphoid cells. | 2020 May |
4 |
| 9 |
32737433 | Oncogenic Smurf1 promotes PTEN wild-type glioblastoma growth by mediating PTEN ubiquitylation. | 2020 Sep |
1 |
| 10 |
33319180 | Differential Regulation of mTOR Complexes with miR-302a Attenuates Myocardial Reperfusion Injury in Diabetes. | 2020 Dec 18 |
2 |
| 11 |
31240704 | High glucose increases miR-214 to power a feedback loop involving PTEN and the Akt/mTORC1 signaling axis. | 2019 Aug |
2 |
| 12 |
31350329 | A Pilot Study of Sirolimus in Subjects with Cowden Syndrome or Other Syndromes Characterized by Germline Mutations in PTEN. | 2019 Dec |
1 |
| 13 |
29844707 | Response to rapamycin analogs but not PD-1 inhibitors in PTEN-mutated metastatic non-small-cell lung cancer with high tumor mutational burden. | 2018 |
1 |
| 14 |
30154635 | Temporal Evolution and Management of Fast Flow Vascular Anomalies in PTEN Hamartoma Tumor Syndrome. | 2018 Sep |
1 |
| 15 |
26992888 | Rapamycin prevents, but does not reverse, aberrant migration in Pten knockout neurons. | 2016 Sep |
1 |
| 16 |
27029073 | Combination of an anti-EGFRvIII antibody CH12 with Rapamycin synergistically inhibits the growth of EGFRvIII+PTEN-glioblastoma in vivo. | 2016 Apr 26 |
1 |
| 17 |
26229595 | Missense mutation in the PTEN promoter of a patient with hemifacial hyperplasia. | 2015 |
1 |
| 18 |
24603487 | PTEN regulates BCRP/ABCG2 and the side population through the PI3K/Akt pathway in chronic myeloid leukemia. | 2014 |
1 |
| 19 |
24764583 | PD-L1 expression in triple-negative breast cancer. | 2014 Apr |
1 |
| 20 |
23989949 | PTEN deficiency is associated with reduced sensitivity to mTOR inhibitor in human bladder cancer through the unhampered feedback loop driving PI3K/Akt activation. | 2013 Sep 17 |
2 |
| 21 |
22137317 | Synergistic activity of rapamycin and dexamethasone in vitro and in vivo in acute lymphoblastic leukemia via cell-cycle arrest and apoptosis. | 2012 Mar |
1 |
| 22 |
22184110 | Unrestrained mammalian target of rapamycin complexes 1 and 2 increase expression of phosphatase and tensin homolog deleted on chromosome 10 to regulate phosphorylation of Akt kinase. | 2012 Feb 3 |
2 |
| 23 |
23139750 | Impaired Pten expression in human malignant peripheral nerve sheath tumours. | 2012 |
1 |
| 24 |
21168265 | Resveratrol enhances the anti-tumor activity of the mTOR inhibitor rapamycin in multiple breast cancer cell lines mainly by suppressing rapamycin-induced AKT signaling. | 2011 Feb 28 |
2 |
| 25 |
21360661 | Oral rapamycin in the treatment of patients with hamartoma syndromes and PTEN mutation. | 2011 Aug |
1 |
| 26 |
21695255 | Mammalian target of rapamycin is a therapeutic target for murine ovarian endometrioid adenocarcinomas with dysregulated Wnt/β-catenin and PTEN. | 2011 |
1 |
| 27 |
21730367 | Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy. | 2011 Jul |
1 |
| 28 |
19917848 | Pancreatic endocrine tumors: expression profiling evidences a role for AKT-mTOR pathway. | 2010 Jan 10 |
1 |
| 29 |
20566381 | Pharmacological inhibition of the mammalian target of rapamycin pathway suppresses acquired epilepsy. | 2010 Oct |
1 |
| 30 |
20863555 | Rapamycin inhibits cell proliferation in type I and type II endometrial carcinomas: a search for biomarkers of sensitivity to treatment. | 2010 Dec |
1 |
| 31 |
20933441 | Mammalian target of rapamycin controls dendritic cell development downstream of Flt3 ligand signaling. | 2010 Oct 29 |
1 |
| 32 |
19139116 | Regulation of D-cyclin translation inhibition in myeloma cells treated with mammalian target of rapamycin inhibitors: rationale for combined treatment with extracellular signal-regulated kinase inhibitors and rapamycin. | 2009 Jan |
2 |
| 33 |
19211884 | Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice. | 2009 Feb 11 |
2 |
| 34 |
19261747 | Inactivation of p53 and Pten promotes invasive bladder cancer. | 2009 Mar 15 |
1 |
| 35 |
17805960 | Activation of the mTOR signaling pathway in breast cancer and its correlation with the clinicopathologic variables. | 2008 Aug |
1 |
| 36 |
18215105 | Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma. | 2008 Jan 22 |
1 |
| 37 |
18303120 | Mechanisms of high-glucose/insulin-mediated desensitization of acute insulin-stimulated glucose transport and Akt activation. | 2008 May |
1 |
| 38 |
18332865 | Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors. | 2008 Jul 3 |
2 |
| 39 |
18431376 | Rapamycin treatment for a child with germline PTEN mutation. | 2008 Jun |
1 |
| 40 |
19115995 | PTEN and rapamycin inhibiting the growth of K562 cells through regulating mTOR signaling pathway. | 2008 Dec 30 |
1 |
| 41 |
16885364 | Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivo. | 2006 Aug 1 |
1 |
| 42 |
16199861 | mTOR controls FLIPS translation and TRAIL sensitivity in glioblastoma multiforme cells. | 2005 Oct |
1 |
| 43 |
15367412 | Reduced PTEN expression in breast cancer cells confers susceptibility to inhibitors of the PI3 kinase/Akt pathway. | 2004 Oct |
1 |
| 44 |
12939469 | Rapamycin inhibits telomerase activity by decreasing the hTERT mRNA level in endometrial cancer cells. | 2003 Aug |
3 |
| 45 |
12414639 | Inhibitors of mTOR reverse doxorubicin resistance conferred by PTEN status in prostate cancer cells. | 2002 Nov 1 |
1 |
| 46 |
12030785 | Mechanisms of resistance to rapamycins. | 2001 Dec |
1 |
| 47 |
10749120 | Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics. | 2000 Mar 15 |
1 |