| 1 |
35439332 | Lipid A Mimetics Based on Unnatural Disaccharide Scaffold as Potent TLR4 Agonists for Prospective Immunotherapeutics and Adjuvants. | 2022 Jun 21 |
1 |
| 2 |
35481682 | T-Cell Activation and LPS: A Dangerous Duo for Organ Dysfunction. | 2022 Apr 28 |
2 |
| 3 |
33815382 | Tailored Modulation of Cellular Pro-inflammatory Responses With Disaccharide Lipid A Mimetics. | 2021 |
1 |
| 4 |
33922017 | The Use of Translational Modelling and Simulation to Develop Immunomodulatory Therapy as an Adjunct to Antibiotic Treatment in the Context of Pneumonia. | 2021 Apr 22 |
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| 5 |
34140078 | [Research progress of TLR4 signaling pathway and its targeted drugs]. | 2021 Jul |
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| 6 |
34246209 | The relationship between the rs4986791 variant of the TLR4 gene and the severity of bronchial asthma in children. | 2021 Jul 11 |
2 |
| 7 |
34382796 | Synthetic Glycolipids as Molecular Vaccine Adjuvants: Mechanism of Action in Human Cells and In Vivo Activity. | 2021 Aug 26 |
2 |
| 8 |
34561306 | Distinct single-component adjuvants steer human DC-mediated T-cell polarization via Toll-like receptor signaling toward a potent antiviral immune response. | 2021 Sep 28 |
1 |
| 9 |
32765484 | Increasing the Chemical Variety of Small-Molecule-Based TLR4 Modulators: An Overview. | 2020 |
1 |
| 10 |
32960056 | Self-Adjuvanting Cancer Vaccines from Conjugation-Ready Lipid A Analogues and Synthetic Long Peptides. | 2020 Oct 22 |
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| 11 |
32974162 | Toll-Like Receptor 4 Expression on Lymphoma Cells Is Critical for Therapeutic Activity of Intratumoral Therapy With Synthetic TLR4 Agonist Glucopyranosyl Lipid A. | 2020 |
2 |
| 12 |
33038865 | New horizons in adjuvants for vaccine development. | 2020 Aug |
1 |
| 13 |
33329561 | Lipopolysaccharide Recognition in the Crossroads of TLR4 and Caspase-4/11 Mediated Inflammatory Pathways. | 2020 |
2 |
| 14 |
30959420 | Structural variants of Salmonella Typhimurium lipopolysaccharide induce less dimerization of TLR4/MD-2 and reduced pro-inflammatory cytokine production in human monocytes. | 2019 Jul |
1 |
| 15 |
31704704 | Substrate structure-activity relationship reveals a limited lipopolysaccharide chemotype range for intestinal alkaline phosphatase. | 2019 Dec 13 |
1 |
| 16 |
29380635 | Recent advances on Toll-like receptor 4 modulation: new therapeutic perspectives. | 2018 Feb |
1 |
| 17 |
29407964 | Rational design of novel TLR4 ligands by in silico screening and their functional and structural characterization in vitro. | 2018 Feb 25 |
1 |
| 18 |
29567797 | Human ALPI deficiency causes inflammatory bowel disease and highlights a key mechanism of gut homeostasis. | 2018 Apr |
1 |
| 19 |
30025492 | Vinorelbine's anti-tumor actions may depend on the mitotic apoptosis, autophagy and inflammation: hypotheses with implications for chemo-immunotherapy of advanced cancers and pediatric gliomas. | 2018 Jul |
2 |
| 20 |
30532257 | Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection. | 2018 Dec |
1 |
| 21 |
28053314 | Comparative Transcriptome Profiles of Human Blood in Response to the Toll-like Receptor 4 Ligands Lipopolysaccharide and Monophosphoryl Lipid A. | 2017 Jan 5 |
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| 22 |
28108356 | Lipid A structural modifications in extreme conditions and identification of unique modifying enzymes to define the Toll-like receptor 4 structure-activity relationship. | 2017 Nov |
5 |
| 23 |
29099761 | The Role of Carbohydrates in the Lipopolysaccharide (LPS)/Toll-Like Receptor 4 (TLR4) Signalling. | 2017 Nov 3 |
6 |
| 24 |
29156775 | Monophosphoryl lipid a attenuates radiation injury through TLR4 activation. | 2017 Oct 17 |
2 |
| 25 |
29190754 | Encryption of agonistic motifs for TLR4 into artificial antigens augmented the maturation of antigen-presenting cells. | 2017 |
2 |
| 26 |
26538529 | Role of G-CSF in monophosphoryl lipid A-mediated augmentation of neutrophil functions after burn injury. | 2016 Apr |
1 |
| 27 |
26555265 | Identification of QS-21 as an Inflammasome-activating Molecular Component of Saponin Adjuvants. | 2016 Jan 15 |
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| 28 |
26669797 | Endothelial cell tolerance to lipopolysaccharide challenge is induced by monophosphoryl lipid A. | 2016 Mar |
2 |
| 29 |
26725501 | Chemical Hybridization of Vizantin and Lipid A to Generate a Novel LPS Antagonist. | 2016 |
1 |
| 30 |
26994069 | Monophosphoryl lipid A-induced pro-inflammatory cytokine expression does not require CD14 in primary human dendritic cells. | 2016 Jun |
1 |
| 31 |
27085175 | Identification of GLA/SE as an effective adjuvant for the induction of robust humoral and cell-mediated immune responses to EBV-gp350 in mice and rabbits. | 2016 May 17 |
1 |
| 32 |
27340679 | A Fusion Protein Consisting of the Vaccine Adjuvant Monophosphoryl Lipid A and the Allergen Ovalbumin Boosts Allergen-Specific Th1, Th2, and Th17 Responses In Vitro. | 2016 |
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| 33 |
27358401 | Dectin-2 Recognizes Mannosylated O-antigens of Human Opportunistic Pathogens and Augments Lipopolysaccharide Activation of Myeloid Cells. | 2016 Aug 19 |
2 |
| 34 |
24838025 | Kdo2 -lipid A: structural diversity and impact on immunopharmacology. | 2015 May |
1 |
| 35 |
24939379 | Molecular simplification of lipid A structure: TLR4-modulating cationic and anionic amphiphiles. | 2015 Feb |
2 |
| 36 |
25037631 | The molecular mechanism of species-specific recognition of lipopolysaccharides by the MD-2/TLR4 receptor complex. | 2015 Feb |
6 |
| 37 |
25536171 | B cell TLR1/2, TLR4, TLR7 and TLR9 interact in induction of class switch DNA recombination: modulation by BCR and CD40, and relevance to T-independent antibody responses. | 2015 Feb |
1 |
| 38 |
26083554 | In situ Delivery of Tumor Antigen- and Adjuvant-Loaded Liposomes Boosts Antigen-Specific T-Cell Responses by Human Dermal Dendritic Cells. | 2015 Nov |
1 |
| 39 |
26160169 | Activation of Human Toll-like Receptor 4 (TLR4)·Myeloid Differentiation Factor 2 (MD-2) by Hypoacylated Lipopolysaccharide from a Clinical Isolate of Burkholderia cenocepacia. | 2015 Aug 28 |
5 |
| 40 |
26198237 | Structure and Effects of Cyanobacterial Lipopolysaccharides. | 2015 Jul 7 |
2 |
| 41 |
26319313 | Species and mediator specific TLR4 antagonism in primary human and murine immune cells by βGlcN(1↔1)αGlc based lipid A mimetics. | 2015 Oct |
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| 42 |
24380872 | The attenuated inflammation of MPL is due to the lack of CD14-dependent tight dimerization of the TLR4/MD2 complex at the plasma membrane. | 2014 Jun |
2 |
| 43 |
24420921 | Tetraacylated lipid A and paclitaxel-selective activation of TLR4/MD-2 conferred through hydrophobic interactions. | 2014 Feb 15 |
3 |
| 44 |
25023285 | Modulation of endotoxicity of Shigella generalized modules for membrane antigens (GMMA) by genetic lipid A modifications: relative activation of TLR4 and TLR2 pathways in different mutants. | 2014 Sep 5 |
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| 45 |
25056632 | Recognition of LPS by TLR4: potential for anti-inflammatory therapies. | 2014 Jul 23 |
3 |
| 46 |
25252784 | Development of αGlcN(1↔1)αMan-based lipid A mimetics as a novel class of potent Toll-like receptor 4 agonists. | 2014 Oct 9 |
6 |
| 47 |
22962435 | Human TLR4 polymorphism D299G/T399I alters TLR4/MD-2 conformation and response to a weak ligand monophosphoryl lipid A. | 2013 Jan |
3 |
| 48 |
23322736 | Toll-like receptor 4 stimulation with the detoxified ligand monophosphoryl lipid A improves Alzheimer's disease-related pathology. | 2013 Jan 29 |
2 |
| 49 |
23408095 | Recognition of lipid A variants by the TLR4-MD-2 receptor complex. | 2013 |
5 |
| 50 |
23447683 | Fast dendritic cells stimulated with alternative maturation mixtures induce polyfunctional and long-lasting activation of innate and adaptive effector cells with tumor-killing capabilities. | 2013 Apr 1 |
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