rottlerin

protein kinase C delta ; Homo sapiens







326 Article(s)
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1 33200225 Dual inhibition of FOXM1 and its compensatory signaling pathway decreased the survival of ovarian cancer cells. 2021 Jan 3
2 34678331 Inhibition of endocytosis of porcine reproductive and respiratory syndrome virus by rottlerin and its potential prophylactic administration in piglets. 2021 Nov 1
3 34698097 Signaling Pathway of Histamine H1 Receptor-Mediated Histamine H1 Receptor Gene Upregulation Induced by Histamine in U-373 MG Cells. 2021 Sep 24 1
4 34924906 Co-administration of tyrosine kinase inhibitors with rottlerin in metastatic prostate cancer cells. 2021 1
5 32125625 Activation of Protein Kinase Cδ Contributes to the Induction of Src/EGF Receptor/ERK Signaling in Ammonia-treated Astrocytes. 2020 Jul 1
6 30813635 Mechanisms of PKC-Mediated Enhancement of HIF-1α Activity and its Inhibition by Vitamin K2 in Hepatocellular Carcinoma Cells. 2019 Feb 26 1
7 31373631 PKCδ Mediates Mineralocorticoid Receptor Activation by Angiotensin II to Modulate Smooth Muscle Cell Function. 2019 Sep 1 2
8 29410069 In vitro identification of mitochondrial oxidative stress production by time-resolved fluorescence imaging of glioma cells. 2018 Apr 1
9 30090653 Pkcδ Activation is Involved in ROS-Mediated Mitochondrial Dysfunction and Apoptosis in Cardiomyocytes Exposed to Advanced Glycation End Products (Ages). 2018 Aug 1
10 30116883 The roles of PKCs in regulating autophagy. 2018 Dec 1
11 30585203 Pro-Inflammatory Stimuli Influence Expression of Intercellular Adhesion Molecule 1 in Human Anulus Fibrosus Cells through FAK/ERK/GSK3 and PKCδ Signaling Pathways. 2018 Dec 25 1
12 31938102 PKCδ reveals a tumor promoter function by promoting cell proliferation and migration in somatotropinomas. 2018 1
13 27427770 The Group I Pak inhibitor Frax-1036 sensitizes 11q13-amplified ovarian cancer cells to the cytotoxic effects of Rottlerin. 2017 Oct 2 1
14 28373118 Synergism between PKCδ regulators hypericin and rottlerin enhances apoptosis in U87 MG glioma cells after light stimulation. 2017 Jun 2
15 28513986 Pleiotropic Effects of Chronic Phorbol Ester Treatment to Improve Glucose Transport in Insulin-Resistant Cardiomyocytes. 2017 Dec 1
16 28539656 PKC-δ isoform plays a crucial role in Tat-TLR4 signalling pathway to activate NF-κB and CXCL8 production. 2017 May 24 1
17 28604588 Docosahexaenoic Acid Induces Expression of Heme Oxygenase-1 and NAD(P)H:quinone Oxidoreductase through Activation of Nrf2 in Human Mammary Epithelial Cells. 2017 Jun 10 1
18 28801242 Oxidant species are involved in T/B-mediated ERK1/2 phosphorylation that activates p53-p21 axis to promote KSHV lytic cycle in PEL cells. 2017 Nov 2
19 28983628 Long intergenic noncoding RNA p21 mediates oxidized LDL‑induced apoptosis and expression of LOX‑1 in human coronary artery endothelial cells. 2017 Dec 1
20 29036789 Protein kinase C δ-dependent regulation of Ubiquitin-proteasome system function in breast cancer. 2017 Dec 12 1
21 29048618 Dual action of NSC606985 on cell growth and apoptosis mediated through PKCδ in prostatic cancer cells. 2017 Nov 1
22 29272319 Rottlerin as a therapeutic approach in psoriasis: Evidence from in vitro and in vivo studies. 2017 1
23 26335446 PKCδ Inhibition Impairs Mammary Cancer Proliferative Capacity But Selects Cancer Stem Cells, Involving Autophagy. 2016 Mar 1
24 27036017 Docosahexaenoic acid inhibits 12-O-tetradecanoylphorbol-13- acetate-induced fascin-1-dependent breast cancer cell migration by suppressing the PKCδ- and Wnt-1/β-catenin-mediated pathways. 2016 May 3 1
25 27065868 Sphingosine 1-Phosphate-Induced ICAM-1 Expression via NADPH Oxidase/ROS-Dependent NF-κB Cascade on Human Pulmonary Alveolar Epithelial Cells. 2016 1
26 27222046 Rottlerin induces cyclooxygenase-2 upregulation through an ATF4 and reactive oxygen species-independent pathway in HEI-OC1 cells. 2016 Jul 1
27 27783407 Efficient PKC inhibitor screening achieved using a quantitative CE-LIF assay. 2016 Dec 1
28 25156550 Dying tumor cells stimulate proliferation of living tumor cells via caspase-dependent protein kinase Cδ activation in pancreatic ductal adenocarcinoma. 2015 Jan 3
29 25592228 Ataxia telangiectasia mutated inhibits oxidative stress-induced apoptosis by regulating heme oxygenase-1 expression. 2015 Mar 1
30 25625567 Activation of PKC-δ in HTLV-1-infected T cells. 2015 Apr 2
31 26398317 Overcoming rituximab drug-resistance by the genetically engineered anti-CD20-hIFN-α fusion protein: Direct cytotoxicity and synergy with chemotherapy. 2015 Nov 1
32 24193916 Targeting elongation factor-2 kinase (eEF-2K) induces apoptosis in human pancreatic cancer cells. 2014 Jan 1
33 24506253 Protein kinase Cδ is a therapeutic target in malignant melanoma with NRAS mutation. 2014 Apr 18 1
34 24626810 Translocation of protein kinase C δ contributes to the moderately high glucose-, but not hypoxia-induced proliferation in primary cultured human retinal endothelial cells. 2014 May 1
35 24814288 FZD1 activates protein kinase C delta-mediated drug-resistance in multidrug-resistant MES-SA/Dx5 cancer cells. 2014 Aug 1
36 25183872 Cdk5 and its substrates, Dcx and p27kip1, regulate cytoplasmic dilation formation and nuclear elongation in migrating neurons. 2014 Sep 1
37 25371776 PKCδ promotes high glucose induced renal tubular oxidative damage via regulating activation and translocation of p66Shc. 2014 2
38 25445591 Protein kinase C regulates vascular calcification via cytoskeleton reorganization and osteogenic signaling. 2014 Oct 31 1
39 22653778 Bradykinin enhances cell migration in human prostate cancer cells through B2 receptor/PKCδ/c-Src dependent signaling pathway. 2013 Jan 1
40 23063429 Protein kinase Cα/β inhibitor Gö6976 promotes PC12 cell adhesion and spreading through membrane recruitment and activation of protein kinase Cδ. 2013 Feb 1 2
41 23532252 PTPα-mediated Src activation by EGF in human breast cancer cells. 2013 Apr 1
42 23988089 PKCδ as a regulator for TGF-β-stimulated connective tissue growth factor production in human hepatocarcinoma (HepG2) cells. 2013 Nov 15 1
43 24289563 PKC?-dependent activation of the ubiquitin proteasome system is responsible for high glucose-induced human breast cancer MCF-7 cell proliferation, migration and invasion. 2013 2
44 24521899 [Role of PKCδ on the phosphorylation and mitochondrial translocation of p66Shc in HK-2 cells induced by high glucose]. 2013 Nov 26 1
45 22052014 PKCδ-dependent activation of ERK1/2 leads to upregulation of the human NHE2 transcriptional activity in intestinal epithelial cell line C2BBe1. 2012 Feb 1 1
46 22364697 The potential of laminin-2-biomimetic short peptide to promote cell adhesion, spreading and migration by inducing membrane recruitment and phosphorylation of PKCδ. 2012 May 1
47 22410117 Rottlerin induces apoptosis of HT29 colon carcinoma cells through NAG-1 upregulation via an ERK and p38 MAPK-dependent and PKC δ-independent mechanism. 2012 Apr 15 5
48 22426323 Regulation of human monocarboxylate transporter 4 in skeletal muscle cells: the role of protein kinase C (PKC). 2012 May 30 1
49 22435755 PKC-δ mediates interferon-α-induced apoptosis through c-Jun NH₂-terminal kinase activation. 2012 Mar 21 1
50 22490701 Rottlerin potentiates camptothecin-induced cytotoxicity in human hormone refractory prostate cancers through increased formation and stabilization of topoisomerase I-DNA cleavage complexes in a PKCδ-independent pathway. 2012 Jul 1 5