Leucine

ribosomal protein S6 kinase B1 ; Rattus norvegicus







27 Article(s)
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1 35334826 Mild Endurance Exercise during Fasting Increases Gastrocnemius Muscle and Prefrontal Cortex Thyroid Hormone Levels through Differential BHB and BCAA-Mediated BDNF-mTOR Signaling in Rats. 2022 Mar 10 1
2 32859884 Protein blend and casein supplementations before inactive phase similarly activate mechanistic target of rapamycin signaling in rat skeletal muscle. 2020 Jul-Aug 1
3 28536139 Effects of leucine supplementation and resistance training on myopathy of diabetic rats. 2017 May 2
4 25960953 Effects of different doses of leucine ingestion following eight weeks of resistance exercise on protein synthesis and hypertrophy of skeletal muscle in rats. 2015 Mar 2
5 25358492 Acute acidosis attenuates leucine stimulated signal transduction and protein synthesis in rat skeletal muscle. 2014 1
6 23563533 Differential dose response of mTOR signaling to oral administration of leucine in skeletal muscle and liver of rats. 2013 2
7 22067655 Insulin resistance due to nutrient excess: is it a consequence of AMPK downregulation? 2011 Oct 15 1
8 19940100 Leucine modulates contraction- and insulin-stimulated glucose transport and upstream signaling events in rat skeletal muscle. 2010 Feb 4
9 20682696 Downregulation of AMPK accompanies leucine- and glucose-induced increases in protein synthesis and insulin resistance in rat skeletal muscle. 2010 Oct 1
10 18234235 Impaired insulin secretion and decreased expression of the nutritionally responsive ribosomal kinase protein S6K-1 in pancreatic islets from malnourished rats. 2008 Feb 27 1
11 18716165 Arginine stimulates cdx2-transformed intestinal epithelial cell migration via a mechanism requiring both nitric oxide and phosphorylation of p70 S6 kinase. 2008 Sep 1
12 18806097 Activation of AMP-activated protein kinase by 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleoside prevents leucine-stimulated protein synthesis in rat skeletal muscle. 2008 Oct 1
13 16616211 Clofibrate treatment promotes branched-chain amino acid catabolism and decreases the phosphorylation state of mTOR, eIF4E-BP1, and S6K1 in rat liver. 2006 Jul 17 1
14 16772439 Leucine activates pancreatic translational machinery in rats and mice through mTOR independently of CCK and insulin. 2006 Jul 2
15 15389631 Endotoxin disrupts the leucine-signaling pathway involving phosphorylation of mTOR, 4E-BP1, and S6K1 in skeletal muscle. 2005 Apr 1
16 15534870 TNFalpha mediates sepsis-induced impairment of basal and leucine-stimulated signaling via S6K1 and eIF4E in cardiac muscle. 2005 Feb 1 2
17 15226457 Leucine regulates translation initiation in rat skeletal muscle via enhanced eIF4G phosphorylation. 2004 Jul 1
18 15377887 Leucine acutely reverses burn-induced alterations in translation initiation in heart. 2004 Oct 1
19 12565877 Inhibition of amino acid-mTOR signaling by a leucine derivative induces G1 arrest in Jurkat cells. 2003 Feb 7 2
20 12944322 Alcohol impairs leucine-mediated phosphorylation of 4E-BP1, S6K1, eIF4G, and mTOR in skeletal muscle. 2003 Dec 2
21 11916909 Orally administered leucine enhances protein synthesis in skeletal muscle of diabetic rats in the absence of increases in 4E-BP1 or S6K1 phosphorylation. 2002 Apr 3
22 11934675 Contribution of insulin to the translational control of protein synthesis in skeletal muscle by leucine. 2002 May 2
23 12026190 Oral administration of leucine stimulates phosphorylation of 4E-bP1 and S6K 1 in skeletal muscle but not in liver of diabetic rats. 2002 Feb 8
24 12153571 Signalling pathways and combinatory effects of insulin and amino acids in isolated rat hepatocytes. 2002 Aug 2
25 11767213 Time course of leucine-induced 4E-BP1 and S6K1 phosphorylation in the liver and skeletal muscle of rats. 2001 Aug 4
26 11015466 Leucine stimulates translation initiation in skeletal muscle of postabsorptive rats via a rapamycin-sensitive pathway. 2000 Oct 1
27 10214966 Structural requirement of leucine for activation of p70 S6 kinase. 1999 Mar 26 11