Amides

beta-secretase 1 ; Homo sapiens







10 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 29966870 Design and synthesis of donepezil analogues as dual AChE and BACE-1 inhibitors. 2018 Oct 1
2 30053756 G-score: A function to solve the puzzle of modeling the protonation states of β-secretase binding pocket. 2018 Oct 1
3 28728106 Multipotent AChE and BACE-1 inhibitors for the treatment of Alzheimer's disease: Design, synthesis and bio-analysis of 7-amino-1,4-dihydro-2H-isoquilin-3-one derivates. 2017 Sep 29 1
4 23735744 BACE1 inhibitors: a head group scan on a series of amides. 2013 Jul 15 2
5 23837729 1,3-Oxazines as BACE1 and/or BACE2 inhibitors: a patent evaluation (WO2012156284). 2013 Aug 1
6 21319811 Coordination features and affinity of the Cu²+ site in the α-synuclein protein of Parkinson's disease. 2011 Mar 22 1
7 21388807 Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors. 2011 Apr 1 1
8 21621412 Triazole-linked reduced amide isosteres: an approach for the fragment-based drug discovery of anti-Alzheimer's BACE1 inhibitors. 2011 Jul 1 1
9 19169270 Discovery of potent beta-secretase (bace-1) inhibitors by the synthesis of isophthalamide-containing hybrids. 2009 Feb 1
10 16690314 BACE-1 inhibition by a series of psi[CH2NH] reduced amide isosteres. 2006 Jul 15 2