UNII-042A8N37WH

beta-secretase 1 ; Homo sapiens







15 Article(s)
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Pub. Year
#Total Relationships
1 32154567 Neuronal Aquaporin 1 Inhibits Amyloidogenesis by Suppressing the Interaction Between Beta-Secretase and Amyloid Precursor Protein. 2021 Jan 1 1
2 30959405 DNA Aptamers Targeting BACE1 Reduce Amyloid Levels and Rescue Neuronal Deficiency in Cultured Cells. 2019 Jun 7 2
3 29142073 GGA1 regulates signal-dependent sorting of BACE1 to recycling endosomes, which moderates Aβ production. 2018 Jan 15 1
4 29477076 Secretase inhibitors for the treatment of Alzheimer's disease: Long road ahead. 2018 Mar 25 1
5 30001606 In vitro neuroprotective effects of naringenin nanoemulsion against β-amyloid toxicity through the regulation of amyloidogenesis and tau phosphorylation. 2018 Oct 15 1
6 30277096 BACE inhibitors in clinical development for the treatment of Alzheimer's disease. 2018 Nov 2
7 27662285 Cyclic cis-Locked Phospho-Dipeptides Reduce Entry of AβPP into Amyloidogenic Processing Pathway. 2017 2
8 28982375 PKR involvement in Alzheimer's disease. 2017 Oct 5 1
9 26092426 PPAR-α agonist regulates amyloid-β generation via inhibiting BACE-1 activity in human neuroblastoma SH-SY5Y cells transfected with APPswe gene. 2015 Oct 1
10 27129013 Population pharmacokinetic and pharmacodynamic analysis of plasma Aβ40 and Aβ42 following single oral doses of the BACE1 inhibitor AZD3839 to healthy volunteers. 2014 Sep 2
11 22842730 L655,240, acting as a competitive BACE1 inhibitor, efficiently decreases β-amyloid peptide production in HEK293-APPswe cells. 2012 Dec 1
12 21738321 Flavonoids lower Alzheimer's Aβ production via an NFκB dependent mechanism. 2011 1
13 19815556 Down-regulation of seladin-1 increases BACE1 levels and activity through enhanced GGA3 depletion during apoptosis. 2009 Dec 4 1
14 15197182 Internalization of exogenously added memapsin 2 (beta-secretase) ectodomain by cells is mediated by amyloid precursor protein. 2004 Sep 3 1
15 11179458 Characterization of recombinant, soluble beta-secretase from an insect cell expression system. 2001 Mar 1