10 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 23585822 | Design and Synthesis of Hydroxyethylene-Based BACE-1 Inhibitors Incorporating Extended P1 Substituents. | 2013 | 2 |
2 | 19995674 | P2'-truncated BACE-1 inhibitors with a novel hydroxethylene-like core. | 2010 Feb | 1 |
3 | 20122837 | Discovery of potent BACE-1 inhibitors containing a new hydroxyethylene (HE) scaffold: exploration of P1' alkoxy residues and an aminoethylene (AE) central core. | 2010 Feb 15 | 4 |
4 | 20128595 | Design and synthesis of potent and selective BACE-1 inhibitors. | 2010 Feb 25 | 2 |
5 | 19169270 | Discovery of potent beta-secretase (bace-1) inhibitors by the synthesis of isophthalamide-containing hybrids. | 2009 Feb | 2 |
6 | 16510290 | Design, synthesis, and evaluation of Leu*Ala hydroxyethylene-based non-peptide beta-secretase (BACE) inhibitors. | 2006 Jul 1 | 2 |
7 | 14695829 | Design and synthesis of hydroxyethylene-based peptidomimetic inhibitors of human beta-secretase. | 2004 Jan 1 | 5 |
8 | 15341936 | Modeling the binding affinities of beta-secretase inhibitors: application to subsite specificity. | 2004 Oct 4 | 2 |
9 | 12458195 | Kinetic studies on beta-site amyloid precursor protein-cleaving enzyme (BACE). Confirmation of an iso mechanism. | 2003 Feb 14 | 2 |
10 | 12206667 | Crystal structure of memapsin 2 (beta-secretase) in complex with an inhibitor OM00-3. | 2002 Sep 10 | 1 |