RO 3306

cyclin dependent kinase 1 ; Homo sapiens







42 Article(s)
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1 35367281 The CDK1 inhibitor, Ro-3306, is a potential antiviral candidate against influenza virus infection. 2022 May 3
2 35443178 DNA replication is highly resilient and persistent under the challenge of mild replication stress. 2022 Apr 19 1
3 32948832 miR-34c-3p targets CDK1 a synthetic lethality partner of KRAS in non-small cell lung cancer. 2021 May 1
4 33556637 TPX2 mediates prostate cancer epithelial-mesenchymal transition through CDK1 regulated phosphorylation of ERK/GSK3β/SNAIL pathway. 2021 Mar 26 1
5 33684621 CDK1 inhibitor controls G2/M phase transition and reverses DNA damage sensitivity. 2021 Apr 23 1
6 33707466 CDK1 is up-regulated by temozolomide in an NF-κB dependent manner in glioblastoma. 2021 Mar 11 2
7 33727226 Integrated Screens Identify CDK1 as a Therapeutic Target in Advanced Gastrointestinal Stromal Tumors. 2021 May 1 3
8 34267439 Relation between Vitamin D Level and Cyclin-Dependent Kinase-1 Gene Expression in Egyptian Patients with Lupus Nephritis and their Impact on Disease Activity. 2021 Mar-Apr 3
9 34435645 Proteasome inhibitors decrease paclitaxel‑induced cell death in nasopharyngeal carcinoma with the accumulation of CDK1/cyclin B1. 2021 Oct 2
10 34611473 Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligase. 2021 Sep 28 1
11 30273737 A fast and reliable protocol for activation of porcine oocytes. 2019 Jan 1 1
12 29233910 Targeting CDK1 and MEK/ERK Overcomes Apoptotic Resistance in BRAF-Mutant Human Colorectal Cancer. 2018 Mar 3
13 29435156 Cis-trimethoxy resveratrol induces intrinsic apoptosis via prometaphase arrest and prolonged CDK1 activation pathway in human Jurkat T cells. 2018 Jan 12 1
14 29760710 Ionizing Radiation Induces Morphological Changes and Immunological Modulation of Jurkat Cells. 2018 1
15 29884303 CDK1 inhibition facilitates formation of syncytiotrophoblasts and expression of human Chorionic Gonadotropin. 2018 Jun 2
16 30045664 CDK1 inhibition sensitizes normal cells to DNA damage in a cell cycle dependent manner. 2018 1
17 30083256 Blocking CDK1/PDK1/β-Catenin signaling by CDK1 inhibitor RO3306 increased the efficacy of sorafenib treatment by targeting cancer stem cells in a preclinical model of hepatocellular carcinoma. 2018 5
18 28434945 Prognostic Biomarker Identification Through Integrating the Gene Signatures of Hepatocellular Carcinoma Properties. 2017 May 1
19 28678347 TRAP1 controls cell cycle G2-M transition through the regulation of CDK1 and MAD2 expression/ubiquitination. 2017 Sep 1
20 26046302 Polo-like kinase 1 inhibition sensitizes neuroblastoma cells for vinca alkaloid-induced apoptosis. 2016 Feb 23 1
21 27050151 Genetically-defined novel oral squamous cell carcinoma cell lines for the development of molecular therapies. 2016 May 10 1
22 27120680 A CIEF-LIF method for simultaneous analysis of multiple protein kinases and screening of inhibitors. 2016 Jul 1
23 27134283 Identification of Candidate Cyclin-dependent kinase 1 (Cdk1) Substrates in Mitosis by Quantitative Phosphoproteomics. 2016 Jul 1
24 27212103 Jumping the nuclear envelop barrier: Improving polyplex-mediated gene transfection efficiency by a selective CDK1 inhibitor RO-3306. 2016 Jul 28 2
25 27385216 Accumulation of cytoplasmic Cdk1 is associated with cancer growth and survival rate in epithelial ovarian cancer. 2016 Aug 2 1
26 25388513 Suppression of homologous recombination sensitizes human tumor cells to IGF-1R inhibition. 2015 Jun 15 2
27 25917079 Eribulin synergizes with Polo-like kinase 1 inhibitors to induce apoptosis in rhabdomyosarcoma. 2015 Aug 28 1
28 24195507 Cyclin-dependent kinase 1 inhibitor RO3306 promotes mitotic slippage in paclitaxel-treated HepG2 cells. 2014 2
29 24321771 Are Orai1 and Orai3 channels more important than calcium influx for cell proliferation? 2014 Feb 1
30 24374180 A specific inhibitor of CDK1, RO-3306, reversibly arrests meiosis during in vitro maturation of porcine oocytes. 2014 Jan 30 3
31 24378347 The CDK1 inhibitor RO3306 improves the response of BRCA-proficient breast cancer cells to PARP inhibition. 2014 Mar 1
32 24626186 Partial inhibition of Cdk1 in G 2 phase overrides the SAC and decouples mitotic events. 2014 2
33 23525902 Chemical genetic analyses of quantitative changes in Cdk1 activity during the human cell cycle. 2013 Jul 15 4
34 24091728 Phosphorylation of eIF4GII and 4E-BP1 in response to nocodazole treatment: a reappraisal of translation initiation during mitosis. 2013 Dec 1 1
35 22071694 Cyclin B1 interacts with the BH3-only protein Bim and mediates its phosphorylation by Cdk1 during mitosis. 2011 Nov 15 1
36 20172609 Differential roles of STIM1, STIM2 and Orai1 in the control of cell proliferation and SOCE amplitude in HEK293 cells. 2010 Apr 1
37 20661218 Restoration of the tumor suppressor p53 by downregulating cyclin B1 in human papillomavirus 16/18-infected cancer cells. 2010 Oct 14 2
38 20736311 Multisite phosphorylation of Erk5 in mitosis. 2010 Sep 15 2
39 20937773 Cdk1/cyclin B1 controls Fas-mediated apoptosis by regulating caspase-8 activity. 2010 Dec 1
40 19822658 Cyclin A2-cyclin-dependent kinase 2 cooperates with the PLK1-SCFbeta-TrCP1-EMI1-anaphase-promoting complex/cyclosome axis to promote genome reduplication in the absence of mitosis. 2009 Dec 2
41 18981479 Differentiation of trophoblast stem cells into giant cells is triggered by p57/Kip2 inhibition of CDK1 activity. 2008 Nov 1 3
42 17172841 Cell cycle synchronization at the G2/M phase border by reversible inhibition of CDK1. 2006 Nov 2