2-Methoxyestradiol

cyclin dependent kinase 1 ; Homo sapiens







9 Article(s)
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1 30797877 Upregulated cyclin B1/CDK1 mediates apoptosis following 2-methoxyestradiol-induced mitotic catastrophe: Role of Bcl-XL phosphorylation. 2019 Oct 4
2 25732194 Dependency of 2-methoxyestradiol-induced mitochondrial apoptosis on mitotic spindle network impairment and prometaphase arrest in human Jurkat T cells. 2015 Apr 15 3
3 22580043 Critical role of cyclin B1/Cdc2 up-regulation in the induction of mitotic prometaphase arrest in human breast cancer cells treated with 2-methoxyestradiol. 2012 Aug 1
4 17410604 In vitro effects of 2-methoxyestradiol on cell morphology and Cdc2 kinase activity in SNO oesophageal carcinoma cells. 2007 May-Jun 1
5 16794187 2-Methoxyestradiol, an estradiol metabolite, inhibits neointima formation and smooth muscle cell growth via double blockade of the cell cycle. 2006 Aug 4 1
6 12690294 Cell cycle block and apoptosis induction in a human melanoma cell line following treatment with 2-methoxyoestradiol: therapeutic implications? 2003 Apr 1
7 11479920 2-methoxyestradiol blocks cell-cycle progression at G(2)/M phase and inhibits growth of human prostate cancer cells. 2001 Jul 1
8 10493943 2-methoxyestradiol-induced growth suppression and lethality in estrogen-responsive MCF-7 cells may be mediated by down regulation of p34cdc2 and cyclin B1 expression. 1999 Oct 2
9 9018099 17beta-Estradiol metabolites affect some regulators of the MCF-7 cell cycle. 1996 Dec 20 3