Threonine

cyclin dependent kinase 1 ; Homo sapiens







177 Article(s)
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1 34791727 Reconstitution and use of highly active human CDK1:Cyclin-B:CKS1 complexes. 2022 Feb 1
2 33593912 ZMYND8 preferentially binds phosphorylated EZH2 to promote a PRC2-dependent to -independent function switch in hypoxia-inducible factor-activated cancer. 2021 Feb 23 1
3 32112098 Acetylation of MORC2 by NAT10 regulates cell-cycle checkpoint control and resistance to DNA-damaging chemotherapy and radiotherapy in breast cancer. 2020 Apr 17 1
4 32214089 CDK1 dependent phosphorylation of hTERT contributes to cancer progression. 2020 Mar 25 1
5 32537408 LncRNA UCA1 Antagonizes Arsenic-Induced Cell Cycle Arrest through Destabilizing EZH2 and Facilitating NFATc2 Expression. 2020 Jun 3
6 32591484 PP2A--B55γ counteracts Cdk1 and regulates proper spindle orientation through the cortical dynein adaptor NuMA. 2020 Jul 31 1
7 32900880 Quantitative kinase and phosphatase profiling reveal that CDK1 phosphorylates PP2Ac to promote mitotic entry. 2020 Sep 8 2
8 30723163 The microtubule-associated protein EML3 regulates mitotic spindle assembly by recruiting the Augmin complex to spindle microtubules. 2019 Apr 5 2
9 31035650 Citrate-Induced p85α⁻PTEN Complex Formation Causes G2/M Phase Arrest in Human Pharyngeal Squamous Carcinoma Cell Lines. 2019 Apr 29 1
10 31434716 Phosphorylation of importin-α1 by CDK1-cyclin B1 controls mitotic spindle assembly. 2019 Sep 23 1
11 31497351 Circular RNA circ-ADD3 inhibits hepatocellular carcinoma metastasis through facilitating EZH2 degradation via CDK1-mediated ubiquitination. 2019 2
12 31822694 Myc stimulates cell cycle progression through the activation of Cdk1 and phosphorylation of p27. 2019 Dec 10 1
13 29576612 Protein kinase A-mediated phosphorylation regulates STAT3 activation and oncogenic EZH2 activity. 2018 Jun 1
14 30039733 The dNTP triphosphohydrolase activity of SAMHD1 persists during S-phase when the enzyme is phosphorylated at T592. 2018 2
15 30317550 Arsenate-mediated G2 cell cycle arrest in U-2OS cells involves phosphorylation of human polycomb protein 2 by p38 MAPK. 2018 Dec 1
16 27716745 The degradation of EZH2 mediated by lncRNA ANCR attenuated the invasion and metastasis of breast cancer. 2017 Jan 2
17 27791484 Regulation of mRNA capping in the cell cycle. 2017 Jan 2 1
18 28401191 Inhibition of EZH2 degradation as a novel approach to overcome drug resistance in acute myeloid leukemia. 2017 2
19 29084198 Distinct kinetics of serine and threonine dephosphorylation are essential for mitosis. 2017 Dec 1
20 27030108 Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability. 2016 Mar 31 1
21 27815502 A Putative Cyclin-binding Motif in Human SAMHD1 Contributes to Protein Phosphorylation, Localization, and Stability. 2016 Dec 16 1
22 25563361 KUD773, a phenylthiazole derivative, displays anticancer activity in human hormone-refractory prostate cancers through inhibition of tubulin polymerization and anti-Aurora A activity. 2015 Jan 7 1
23 25604483 Identification of non-Ser/Thr-Pro consensus motifs for Cdk1 and their roles in mitotic regulation of C2H2 zinc finger proteins and Ect2. 2015 Jan 21 2
24 25732194 Dependency of 2-methoxyestradiol-induced mitochondrial apoptosis on mitotic spindle network impairment and prometaphase arrest in human Jurkat T cells. 2015 Apr 15 3
25 25847232 CyclinA2-Cyclin-dependent Kinase Regulates SAMHD1 Protein Phosphohydrolase Domain. 2015 May 22 1
26 25994054 Morphological, cellular and molecular changes during postovulatory egg aging in mammals. 2015 May 22 2
27 26023773 Cooperative Action of Cdk1/cyclin B and SIRT1 Is Required for Mitotic Repression of rRNA Synthesis. 2015 May 1
28 26131711 Two Distinct Cdc2 Pools Regulate Cell Cycle Progression and the DNA Damage Response in the Fission Yeast S.pombe. 2015 2
29 24623419 Identification of cellular proteins interacting with the retroviral restriction factor SAMHD1. 2014 May 3
30 25545367 Cdk1-mediated phosphorylation of human ATF7 at Thr-51 and Thr-53 promotes cell-cycle progression into M phase. 2014 6
31 23323858 HER2 stabilizes survivin while concomitantly down-regulating survivin gene transcription by suppressing Notch cleavage. 2013 Apr 1 1
32 23500464 Mitotic phosphorylation of VCIP135 blocks p97ATPase-mediated Golgi membrane fusion. 2013 Apr 5 1
33 23602554 Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1. 2013 Apr 25 1
34 23671119 Essential role for Cdk2 inhibitory phosphorylation during replication stress revealed by a human Cdk2 knockin mutation. 2013 May 28 1
35 23707954 Prometaphase arrest-dependent phosphorylation of Bcl-2 family proteins and activation of mitochondrial apoptotic pathway are associated with 17α-estradiol-induced apoptosis in human Jurkat T cells. 2013 Oct 1
36 23775190 The tumor suppressor CDKN3 controls mitosis. 2013 Jun 24 2
37 23802687 In vitro and in vivo antiproliferative effect of a combination of ultraviolet-A and alkoxy furocoumarins isolated from Umbelliferae medicinal plants, in melanoma cells. 2013 Sep-Oct 1
38 23870088 Identification of the lamin A/C phosphoepitope recognized by the antibody P-STM in mitotic HeLa S3 cells. 2013 Jul 19 2
39 21331744 In vitro antitumor mechanism of a novel cyclin-dependent kinase inhibitor CDKI-83. 2012 Jun 1
40 22266860 Sp1 phosphorylation by cyclin-dependent kinase 1/cyclin B1 represses its DNA-binding activity during mitosis in cancer cells. 2012 Nov 22 1
41 22580740 Pirarubicin inhibits multidrug-resistant osteosarcoma cell proliferation through induction of G2/M phase cell cycle arrest. 2012 Jun 2
42 22753416 Furry protein promotes aurora A-mediated Polo-like kinase 1 activation. 2012 Aug 10 1
43 23063527 Gravin is a transitory effector of polo-like kinase 1 during cell division. 2012 Nov 30 1
44 21131960 CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells. 2011 Jan 3
45 21238919 Epigenetic memory meets G2/M: to remember or to forget? 2011 Jan 18 1
46 21278485 Phosphorylation of EZH2 by CDK1 and CDK2: a possible regulatory mechanism of transmission of the H3K27me3 epigenetic mark through cell divisions. 2011 Feb 15 1
47 21321122 Human papillomavirus (HPV) E7 induces prolonged G2 following S phase reentry in differentiated human keratinocytes. 2011 Apr 29 1
48 21331449 Gambogic acid inhibits the growth of osteosarcoma cells in vitro by inducing apoptosis and cell cycle arrest. 2011 May 1
49 21498573 The initial phase of chromosome condensation requires Cdk1-mediated phosphorylation of the CAP-D3 subunit of condensin II. 2011 Apr 15 1
50 21659531 Cyclin-dependent kinase 1 (CDK1)-mediated phosphorylation of enhancer of zeste 2 (Ezh2) regulates its stability. 2011 Aug 12 1