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28176922 | Inhibition of Skp2 sensitizes lung cancer cells to paclitaxel. | 2017 |
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23943501 | The Cdk inhibitor flavopiridol enhances temozolomide-induced cytotoxicity in human glioma cells. | 2013 Nov |
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20419498 | Homology modeling, molecular dynamic simulation and docking studies of cyclin dependent kinase 1. | 2011 Feb |
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21885916 | VMY-1-103 is a novel CDK inhibitor that disrupts chromosome organization and delays metaphase progression in medulloblastoma cells. | 2011 Nov 1 |
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20206141 | Sequential treatment with flavopiridol synergistically enhances pyrrolo-1,5-benzoxazepine-induced apoptosis in human chronic myeloid leukaemia cells including those resistant to imatinib treatment. | 2010 Jul 1 |
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21042745 | Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce cell cycle arrest and apoptosis in prostate cancer cells. | 2010 Dec |
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17638911 | Histone deacetylase inhibitors enhance lexatumumab-induced apoptosis via a p21Cip1-dependent decrease in survivin levels. | 2007 Jul 15 |
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14751090 | Small molecule inhibitors targeting cyclin-dependent kinases as anticancer agents. | 2004 Mar |
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15023361 | Effects of pharmacological cyclin-dependent kinase inhibitors on viral transcription and replication. | 2004 Mar 11 |
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15217973 | Preclinical and clinical development of the cyclin-dependent kinase inhibitor flavopiridol. | 2004 Jun 15 |
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15308730 | Roscovitine inhibits activation of promoters in herpes simplex virus type 1 genomes independently of promoter-specific factors. | 2004 Sep |
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15474478 | Molecular models of cyclin-dependent kinase 1 complexed with inhibitors. | 2004 Nov 12 |
6 |
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12813134 | Flavopiridol enhances the effect of docetaxel in vitro and in vivo in human gastric cancer cells. | 2003 Jun |
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14519054 | Clinical pharmacology of flavopiridol following a 72-hour continuous infusion. | 2003 Oct |
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14562039 | Proteasome inhibitors potentiate leukemic cell apoptosis induced by the cyclin-dependent kinase inhibitor flavopiridol through a SAPK/JNK- and NF-kappaB-dependent process. | 2003 Oct 16 |
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11960485 | Structure-based design and synthesis of 2-benzylidene-benzofuran-3-ones as flavopiridol mimics. | 2002 Apr 25 |
2 |
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12054639 | Structural basis for inhibition of cyclin-dependent kinase 9 by flavopiridol. | 2002 Apr 26 |
4 |
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11464216 | The cyclin-dependent kinase inhibitor flavopiridol induces apoptosis in human leukemia cells (U937) through the mitochondrial rather than the receptor-mediated pathway. | 2001 Jul |
2 |
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11063609 | Thio- and oxoflavopiridols, cyclin-dependent kinase 1-selective inhibitors: synthesis and biological effects. | 2000 Nov 2 |
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10363974 | Discovery and initial characterization of the paullones, a novel class of small-molecule inhibitors of cyclin-dependent kinases. | 1999 Jun 1 |
2 |
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10500810 | Synthetic cyclin dependent kinase inhibitors. New generation of potent anti-cancer drugs. | 1999 |
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10665481 | Flavopiridol: the first cyclin-dependent kinase inhibitor in human clinical trials. | 1999 |
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16127615 | Small molecule anticancer drugs. | 1999 Jun |
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9427698 | Early induction of apoptosis in hematopoietic cell lines after exposure to flavopiridol. | 1998 Jan 15 |
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9802881 | Flavopiridol, a novel cyclin-dependent kinase inhibitor, suppresses the growth of head and neck squamous cell carcinomas by inducing apoptosis. | 1998 Nov 1 |
2 |
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8674031 | Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells. | 1996 Jul 1 |
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8895733 | Flavopiridol: a cytotoxic flavone that induces cell death in noncycling A549 human lung carcinoma cells. | 1996 Nov 1 |
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21541623 | Flavopiridol (L86 8275; NSC 649890), a new kinase inhibitor for tumor therapy. | 1996 Dec |
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