| 1 |
34034210 | Therapy-related acute myeloid leukemia with KMT2A-SNX9 gene fusion associated with a hyperdiploid karyotype after hemophagocytic lymphohistiocytosis. | 2021 Aug |
1 |
| 2 |
32216001 | Gene rearrangements of MLL and RUNX1 sporadically occur in normal CD34+ cells under cytokine stimulation. | 2020 May |
1 |
| 3 |
30387535 | Bioflavonoids promote stable translocations between MLL-AF9 breakpoint cluster regions independent of normal chromosomal context: Model system to screen environmental risks. | 2019 Mar |
2 |
| 4 |
27813122 | Quercetin alters the DNA damage response in human hematopoietic stem and progenitor cells via TopoII- and PI3K-dependent mechanisms synergizing in leukemogenic rearrangements. | 2017 Feb 15 |
1 |
| 5 |
27974636 | Myeloperoxidase Enhances Etoposide and Mitoxantrone-Mediated DNA Damage: A Target for Myeloprotection in Cancer Chemotherapy. | 2017 Jan |
1 |
| 6 |
32300400 | Infiltrative Rash Secondary to Leukemic-Phase Diffuse Large B-Cell Lymphoma With t(14;18), CDKN2A and MLL Deletion. | 2017 Oct |
1 |
| 7 |
27119507 | Expression of MLL-AF4 or AF4-MLL fusions does not impact the efficiency of DNA damage repair. | 2016 May 24 |
1 |
| 8 |
27473573 | Acute myeloid leukemia following etoposide therapy for EBV-associated hemophagocytic lymphohistiocytosis: a case report and a brief review of the literature. | 2016 Jul 29 |
1 |
| 9 |
27913458 | Therapy-related myeloid neoplasms: does knowing the origin help to guide treatment? | 2016 Dec 2 |
1 |
| 10 |
26657054 | Dysregulation of the DNA Damage Response and KMT2A Rearrangement in Fetal Liver Hematopoietic Cells. | 2015 |
4 |
| 11 |
24766193 | Etoposide quinone is a covalent poison of human topoisomerase IIβ. | 2014 May 20 |
1 |
| 12 |
24858818 | DOT1L inhibition sensitizes MLL-rearranged AML to chemotherapy. | 2014 |
1 |
| 13 |
24086652 | The broken MLL gene is frequently located outside the inherent chromosome territory in human lymphoid cells treated with DNA topoisomerase II poison etoposide. | 2013 |
4 |
| 14 |
22615413 | Model for MLL translocations in therapy-related leukemia involving topoisomerase IIβ-mediated DNA strand breaks and gene proximity. | 2012 Jun 5 |
4 |
| 15 |
22851953 | Secondary leukemia associated with the anti-cancer agent, etoposide, a topoisomerase II inhibitor. | 2012 Jul |
2 |
| 16 |
21135858 | Insights into the cellular origin and etiology of the infant pro-B acute lymphoblastic leukemia with MLL-AF4 rearrangement. | 2011 Mar |
2 |
| 17 |
21048951 | ATM modulates the loading of recombination proteins onto a chromosomal translocation breakpoint hotspot. | 2010 Oct 27 |
1 |
| 18 |
19587093 | Etoposide induces MLL rearrangements and other chromosomal abnormalities in human embryonic stem cells. | 2009 Sep |
4 |
| 19 |
21637660 | Preferential induction of MLL(Mixed Lineage Leukemia) rearrangements in human lymphocyte cultures treated with etoposide. | 2009 Jan |
2 |
| 20 |
18509329 | Etoposide sensitivity does not predict MLL rearrangements or risk of therapy-related acute myeloid leukemia. | 2008 Dec |
1 |
| 21 |
18510699 | Etoposide-initiated MLL rearrangements detected at high frequency in human primitive hematopoietic stem cells with in vitro and in vivo long-term repopulating potential. | 2008 Sep |
5 |
| 22 |
18774953 | Etoposide-initiated MLL rearrangements: the pitfalls of inverse PCR. | 2008 Dec |
1 |
| 23 |
17332306 | Synergism between etoposide and 17-AAG in leukemia cells: critical roles for Hsp90, FLT3, topoisomerase II, Chk1, and Rad51. | 2007 Mar 1 |
1 |
| 24 |
17673902 | Genome scan implicates adhesion biological pathways in secondary leukemia. | 2007 Oct |
1 |
| 25 |
16377807 | MLL rearrangements are induced by low doses of etoposide in human fetal hematopoietic stem cells. | 2006 Apr |
3 |
| 26 |
16434323 | Genotoxicity of etoposide: greater susceptibility of MLL than other target genes. | 2006 Jan 15 |
3 |
| 27 |
16809075 | Etoposide and illegitimate DNA double-strand break repair in the generation of MLL translocations: new insights and new questions. | 2006 Sep 8 |
2 |
| 28 |
15528316 | Therapy-related acute myeloid leukemia-like MLL rearrangements are induced by etoposide in primary human CD34+ cells and remain stable after clonal expansion. | 2005 Mar 1 |
5 |
| 29 |
14630694 | Etoposide induces chimeric Mll gene fusions. | 2004 Jan |
2 |
| 30 |
14742315 | Recombination at chromosomal sequences involved in leukaemogenic rearrangements is differentially regulated by p53. | 2004 Aug |
2 |
| 31 |
14970849 | ALL-1/MLL1, a homologue of Drosophila TRITHORAX, modifies chromatin and is directly involved in infant acute leukaemia. | 2004 Feb 23 |
1 |
| 32 |
14990976 | Modulation of cell cycle by graded expression of MLL-AF4 fusion oncoprotein. | 2004 Jun |
1 |
| 33 |
15319341 | Kinetics and regulation of cytochrome P450-mediated etoposide metabolism. | 2004 Sep |
1 |
| 34 |
14627986 | Reciprocal DNA topoisomerase II cleavage events at 5'-TATTA-3' sequences in MLL and AF-9 create homologous single-stranded overhangs that anneal to form der(11) and der(9) genomic breakpoint junctions in treatment-related AML without further processing. | 2003 Nov 20 |
1 |
| 35 |
11170441 | Etoposide metabolites enhance DNA topoisomerase II cleavage near leukemia-associated MLL translocation breakpoints. | 2001 Feb 6 |
2 |
| 36 |
11313693 | Aggressive neoplastic plasma cell growth with MLL gene rearrangement after high-dose therapy with autologous stem cell support for multiple myeloma. | 2001 Mar |
1 |
| 37 |
11406628 | Nucleolytic cleavage of the mixed lineage leukemia breakpoint cluster region during apoptosis. | 2001 Aug 24 |
4 |
| 38 |
11473400 | Simultaneous determination of etoposide and its catechol metabolite in the plasma of pediatric patients by liquid chromatography/tandem mass spectrometry. | 2001 Jul |
1 |
| 39 |
10758153 | Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia. | 2000 Apr 25 |
5 |
| 40 |
9199342 | DNA cleavage within the MLL breakpoint cluster region is a specific event which occurs as part of higher-order chromatin fragmentation during the initial stages of apoptosis. | 1997 Jul |
1 |
| 41 |
8960661 | [Three cases of secondary acute myeloid leukemia after long-term treatment with oral etoposide]. | 1996 Nov |
1 |
| 42 |
7948964 | Acute myelomonocytic leukemia after treatment with chronic oral etoposide: are MLL and LTG9 genes targets for etoposide? | 1994 Aug |
2 |