Bleomycin

transforming growth factor, beta 1 ; Rattus norvegicus







58 Article(s)
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1 34758440 1β-Hydroxyalantolactone from Inulae Flos alleviated the progression of pulmonary fibrosis via inhibiting JNK/FOXO1/NF-κB pathway. 2021 Dec 1
2 32377772 Zingerone ameliorates oxidative stress and inflammation in bleomycin-induced pulmonary fibrosis: modulation of the expression of TGF-β1 and iNOS. 2020 Sep 1
3 32440328 Beneficial effects of N-acetylcysteine on protease-antiprotease balance in attenuating bleomycin-induced pulmonary fibrosis in rats. 2020 Mar 1
4 30719057 Yangyin Yiqi Mixture Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Rats through Inhibiting TGF-β1/Smad Pathway and Epithelial to Mesenchymal Transition. 2019 1
5 31210057 Peptide PD29 treats bleomycin-induced pulmonary fibrosis by inhibiting the TGF-β/smad signaling pathway. 2019 May - Aug 1
6 31250599 [Effects of Yiqi Huayu Hutan decoction on pulmonary fibrosis in rats and its mechanism]. 2019 Feb 2
7 31535412 Hydrogen inhalation attenuated bleomycin-induced pulmonary fibrosis by inhibiting transforming growth factor-β1 and relevant oxidative stress and epithelial-to-mesenchymal transition. 2019 Dec 2
8 31611754 Hesperidin ameliorates bleomycin-induced experimental pulmonary fibrosis via inhibition of TGF-beta1/Smad3/AMPK and IkappaBalpha/NF-kappaB pathways. 2019 3
9 29793317 Metformin alleviates bleomycin-induced pulmonary fibrosis in rats: Pharmacological effects and molecular mechanisms. 2018 Jan 1
10 30030077 Polysaccharides from Dendrobium officinale inhibit bleomycin-induced pulmonary fibrosis via the TGFβ1-Smad2/3 axis. 2018 Oct 15 2
11 30186404 Pirfenidone suppresses bleomycin-induced pulmonary fibrosis and periostin expression in rats. 2018 Sep 1
12 28077319 Role of insulin like growth factor axis in the bleomycin induced lung injury in rats. 2017 Feb 2
13 26817817 Astragalus injection attenuates bleomycin-induced pulmonary fibrosis via down-regulating Jagged1/Notch1 in lungs. 2016 Mar 1
14 26889245 Apigenin protects against bleomycin-induced lung fibrosis in rats. 2016 Jan 1
15 27556497 Calcitonin gene-related peptide down-regulates bleomycin-induced pulmonary fibrosis. 2016 Dec 1
16 27774992 Emodin ameliorates bleomycin-induced pulmonary fibrosis in rats by suppressing epithelial-mesenchymal transition and fibroblast activation. 2016 Oct 24 1
17 25636879 Total extract of Yupingfeng attenuates bleomycin-induced pulmonary fibrosis in rats. 2015 Jan 15 1
18 25877860 Berberine inhibits Smad and non-Smad signaling cascades and enhances autophagy against pulmonary fibrosis. 2015 Sep 1
19 26330752 Amelioration of Bleomycin-induced Pulmonary Fibrosis of Rats by an Aldose Reductase Inhibitor, Epalrestat. 2015 Sep 1
20 26629034 Magnolol reduces bleomycin-induced rodent lung fibrosis. 2015 2
21 24769130 Daidzein exhibits anti-fibrotic effect by reducing the expressions of Proteinase activated receptor 2 and TGFβ1/smad mediated inflammation and apoptosis in Bleomycin-induced experimental pulmonary fibrosis. 2014 Aug 1
22 25209833 Total polysaccharide of Yupingfeng protects against bleomycin-induced pulmonary fibrosis via inhibiting transforming growth factor-β1-mediated type I collagen abnormal deposition in rats. 2014 Dec 1
23 23523661 Baicalein attenuates bleomycin-induced pulmonary fibrosis in rats through inhibition of miR-21. 2013 Dec 1
24 24011153 [Effect of compound panax notoginsenoside granules on TGF-β1/Smads signaling pathway in rats with bleomycin-induced pulmonary fibrosis]. 2013 Sep 1
25 24028731 [Anti-fibrotic effects of angiotensin1-7 on bleomycin-induced pulmonary fibrosis in rats]. 2013 May 28 1
26 24042439 All-transretinoic acid ameliorates bleomycin-induced lung fibrosis by downregulating the TGF-β1/Smad3 signaling pathway in rats. 2013 Nov 1
27 22558986 [Effect of Budesonide on Smad4, PDGF-A and PAI-1 in a rat model of pulmonary fibrosis]. 2012 May 1
28 22659583 Evaluation of the antifibrotic effect of fenofibrate and rosiglitazone on bleomycin-induced pulmonary fibrosis in rats. 2012 Aug 15 1
29 21520061 Pulmonary microvascular endothelial cells from bleomycin-induced rats promote the transformation and collagen synthesis of fibroblasts. 2011 Aug 1
30 19513812 Inhibition of latent transforming growth factor-beta1 activation by lentivirus-mediated short hairpin RNA targeting the CD36 gene in NR8383 cells. 2010 Mar 1
31 18722097 A TSP-1 functional fragment inhibits activation of latent transforming growth factor-beta1 derived from rat alveolar macrophage after bleomycin treatment. 2009 Jan 2
32 19154443 Roflumilast, a phosphodiesterase 4 inhibitor, alleviates bleomycin-induced lung injury. 2009 Feb 2
33 18589176 Therapeutic effects of bone marrow-derived mesenchymal stem cells engraftment on bleomycin-induced lung injury in rats. 2008 Jun 1
34 18727865 [Effect of curcumin on the expression of collagen type I protein and transforming growth factor-beta1 mRNA in pulmonary fibrosis rats]. 2008 May 2
35 17572999 [The effect of curcumin on bleomycin-induced pulmonary fibrosis in rats]. 2007 Mar 1
36 15920145 Gender-based differences in bleomycin-induced pulmonary fibrosis. 2005 Jun 1
37 16335208 [Effects of moxibustion at Feishu (BL 13) and Gaohuang (BL 43) on expression of TGF-beta1 in the bleomycin -induced pulmonary fibrosis]. 2005 Nov 2
38 12930837 Transforming growth factor-beta1 decreases expression of the epithelial sodium channel alphaENaC and alveolar epithelial vectorial sodium and fluid transport via an ERK1/2-dependent mechanism. 2003 Nov 7 2
39 11936776 Differential expression of transforming growth factor-beta type I and II receptors by pulmonary cells in bleomycin-induced lung injury: correlation with repair and fibrosis. 2002 Apr-May 2
40 12192538 Suppression of in vivo tumorigenicity of rat hepatoma cell line KDH-8 cells by soluble TGF-beta receptor type II. 2002 Sep 1
41 10487979 Activation of rat alveolar macrophage-derived latent transforming growth factor beta-1 by plasmin requires interaction with thrombospondin-1 and its cell surface receptor, CD36. 1999 Sep 1
42 10502292 Promoter competitors as novel antifibrotics that inhibit transforming growth factor-beta induction of collagen and noncollagen protein synthesis in fibroblasts. 1999 Nov 1 1
43 11820952 [The effect of anti-transforming growth factor-beta1 antibody on fibroblast proliferation in vitro]. 1999 Feb 3
44 9390197 Restoration of macrophage tumoricidal activity by bleomycin correlates with the decreased production of transforming growth factor beta in rats bearing KDH-8 hepatoma cells. 1997 Oct 1
45 10374444 [The therapeutic effect of TGF-beta monoclonal antibody to bleomycin-induced pulmonary fibrosis in rats]. 1997 Dec 3
46 8579115 Lung fibroblast alpha-smooth muscle actin expression and contractile phenotype in bleomycin-induced pulmonary fibrosis. 1996 Feb 1
47 8612529 Type I procollagen production and cell proliferation is mediated by transforming growth factor-beta in a model of hepatic fibrosis. 1996 May 6
48 8703482 Plasmin regulates the activation of cell-associated latent TGF-beta 1 secreted by rat alveolar macrophages after in vivo bleomycin injury. 1996 Aug 4
49 9206100 Expression of TGF-beta 1, PDGF and IGF-1 mRNA in lung of bleomycin-A5-induced pulmonary fibrosis in rats. 1996 Jul 1
50 7543734 Cellular localization of transforming growth factor-beta expression in bleomycin-induced pulmonary fibrosis. 1995 Aug 2