| 1 |
35202654 | Tissue-specific alternative splicing separates the catalytic and cell signaling functions of human leucyl-tRNA synthetase. | 2022 Apr |
1 |
| 2 |
35614056 | O-GlcNAc modification of leucyl-tRNA synthetase 1 integrates leucine and glucose availability to regulate mTORC1 and the metabolic fate of leucine. | 2022 May 25 |
8 |
| 3 |
33091505 | Aminoacyl-tRNA synthetases and amino acid signaling. | 2021 Jan |
1 |
| 4 |
33300650 | Severe course with lethal hepatocellular injury and skeletal muscular dysgenesis in a neonate with infantile liver failure syndrome type 1 caused by novel LARS1 mutations. | 2021 Mar |
1 |
| 5 |
33863987 | Leucyl-tRNA synthetase deficiency systemically induces excessive autophagy in zebrafish. | 2021 Apr 16 |
1 |
| 6 |
33869199 | Advances in the Role of Leucine-Sensing in the Regulation of Protein Synthesis in Aging Skeletal Muscle. | 2021 |
2 |
| 7 |
33910001 | Leucine-sensing mechanism of leucyl-tRNA synthetase 1 for mTORC1 activation. | 2021 Apr 27 |
11 |
| 8 |
33979735 | Structure-based modification of pyrazolone derivatives to inhibit mTORC1 by targeting the leucyl-tRNA synthetase-RagD interaction. | 2021 Jul |
1 |
| 9 |
34258600 | Protocol for improving diffraction quality of leucyl-tRNA synthetase 1 with methylation and post-crystallization soaking and cooling in cryoprotectants. | 2021 Sep 17 |
1 |
| 10 |
34325132 | Leucyl-tRNA synthetase 1 is required for proliferation of TSC-null cells. | 2021 Sep 24 |
2 |
| 11 |
34496286 | Deep phenotyping of MARS1 (interstitial lung and liver disease) and LARS1 (infantile liver failure syndrome 1) recessive multisystemic disease using Human Phenotype Ontology annotation: Overlap and differences. Case report and review of literature. | 2021 Nov |
1 |
| 12 |
31924757 | PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase. | 2020 Jan 10 |
1 |
| 13 |
32820315 | [The role and mechanism of leucyl-tRNA synthetase in the regulation of protein synthesis in aging skeletal muscle]. | 2020 Aug 25 |
3 |
| 14 |
30985292 | Nontranslational function of leucyl-tRNA synthetase regulates myogenic differentiation and skeletal muscle regeneration. | 2019 Apr 15 |
1 |
| 15 |
29425714 | Leucyl-tRNA synthetase is required for the myogenic differentiation of C2C12 myoblasts, but not for hypertrophy or metabolic alteration of myotubes. | 2018 Mar 15 |
1 |
| 16 |
29784813 | Coordination of the leucine-sensing Rag GTPase cycle by leucyl-tRNA synthetase in the mTORC1 signaling pathway. | 2018 Jun 5 |
2 |
| 17 |
30041947 | Discovery of novel leucyladenylate sulfamate surrogates as leucyl-tRNA synthetase (LRS)-targeted mammalian target of rapamycin complex 1 (mTORC1) inhibitors. | 2018 Aug 7 |
2 |
| 18 |
28882589 | Leucine-induced localization of Leucyl-tRNA synthetase in lysosome membrane. | 2017 Nov 18 |
3 |
| 19 |
28963468 | Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction. | 2017 Sep 29 |
7 |
| 20 |
27209231 | Discovery of (S)-4-isobutyloxazolidin-2-one as a novel leucyl-tRNA synthetase (LRS)-targeted mTORC1 inhibitor. | 2016 Jul 1 |
1 |
| 21 |
27477288 | Leucyl-tRNA Synthetase Activates Vps34 in Amino Acid-Sensing mTORC1 Signaling. | 2016 Aug 9 |
2 |
| 22 |
27933890 | Discovery of Leucyladenylate Sulfamates as Novel Leucyl-tRNA Synthetase (LRS)-Targeted Mammalian Target of Rapamycin Complex 1 (mTORC1) Inhibitors. | 2016 Nov 23 |
1 |
| 23 |
22424774 | Leucyl-tRNA synthetase controls TORC1 via the EGO complex. | 2012 Apr 13 |
2 |
| 24 |
22424946 | Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway. | 2012 Apr 13 |
4 |
| 25 |
22525334 | Leucyl-tRNA synthetase: double duty in amino acid sensing. | 2012 Aug |
1 |
| 26 |
20805241 | Modular pathways for editing non-cognate amino acids by human cytoplasmic leucyl-tRNA synthetase. | 2011 Jan |
1 |
| 27 |
20482517 | Functional characterization of leucine-specific domain 1 from eukaryal and archaeal leucyl-tRNA synthetases. | 2010 Aug 1 |
2 |
| 28 |
19426743 | Crystal structures of the human and fungal cytosolic Leucyl-tRNA synthetase editing domains: A structural basis for the rational design of antifungal benzoxaboroles. | 2009 Jul 10 |
2 |
| 29 |
422660 | The effect of amino acids on the temperature sensitive phenotype of the mammalian leucyl-tRNA synthetase mutant tsHl and its revertants. | 1979 Feb |
1 |
| 30 |
422661 | Isolation and characterization of revertants of the mammalian temperature sensitive leucyl-tRNA synthetase mutant tsHl. | 1979 Feb |
1 |
| 31 |
139609 | Proposed involvement of an internal promoter in regulation and synthesis of mitochondrial and cytoplasmic leucyl-tRNA synthetases of Neurospora. | 1977 Mar |
2 |
| 32 |
1168198 | Effect of leucine on the temperature sensitive phenotype of a mammalian leucyl-tRNA synthetase mutant. | 1975 Apr |
1 |