| 1 |
33378196 | (+/-)-Borneol Reverses Mitoxantrone Resistance against P-Glycoprotein. | 2021 Jan 25 |
4 |
| 2 |
30353640 | Determination of Reference Values of MDR-ABC Transporter Activities in CD3+ Lymphocytes of Healthy Volunteers Using a Flow Cytometry Based Method. | 2019 Nov |
2 |
| 3 |
31039321 | Confirmation of Selected Synergistic Cancer Drug Combinations Identified in an HTS Campaign and Exploration of Drug Efflux Transporter Contributions to the Mode of Synergy. | 2019 Jul |
1 |
| 4 |
31048454 | Coexpression of ABCB1 and ABCG2 in a Cell Line Model Reveals Both Independent and Additive Transporter Function. | 2019 Jul |
2 |
| 5 |
31476282 | Derivative of 5-cyano-6-phenylpyrimidin antagonizes ABCB1- and ABCG2-mediated multidrug resistance. | 2019 Nov 15 |
1 |
| 6 |
30544754 | A Novel Synthetic Dihydroindeno[1,2-b] Indole Derivative (LS-2-3j) Reverses ABCB1- and ABCG2-Mediated Multidrug Resistance in Cancer Cells. | 2018 Dec 10 |
1 |
| 7 |
28712845 | Dual inhibitors of the human blood-brain barrier drug efflux transporters P-glycoprotein and ABCG2 based on the antiviral azidothymidine. | 2017 Oct 1 |
1 |
| 8 |
28912036 | Dual effects of the PI3K inhibitor ZSTK474 on multidrug efflux pumps in resistant cancer cells. | 2017 Nov 15 |
1 |
| 9 |
26622052 | Using the BacMam Baculovirus System to Study Expression and Function of Recombinant Efflux Drug Transporters in Polarized Epithelial Cell Monolayers. | 2016 Feb |
2 |
| 10 |
26651362 | IPEC-J2 MDR1, a Novel High-Resistance Cell Line with Functional Expression of Human P-glycoprotein (ABCB1) for Drug Screening Studies. | 2016 Feb 1 |
1 |
| 11 |
27479651 | The expression of P-glycoprotein in leukemia cells is associated with the upregulated expression of nestin, a class 6 filament protein. | 2016 Sep |
3 |
| 12 |
26002042 | Selection of resistant acute myeloid leukemia SKM-1 and MOLM-13 cells by vincristine-, mitoxantrone- and lenalidomide-induced upregulation of P-glycoprotein activity and downregulation of CD33 cell surface exposure. | 2015 Sep 18 |
2 |
| 13 |
26002514 | Identification of prognostic subgroups among acute myeloid leukemia patients with intermediate risk cytogenetics using a flow-cytometry-based assessment of ABC-transporter function. | 2015 Jul |
1 |
| 14 |
24305879 | MDR1 synonymous polymorphisms alter transporter specificity and protein stability in a stable epithelial monolayer. | 2014 Jan 15 |
4 |
| 15 |
22451016 | A physiologically based pharmacokinetic model of mitoxantrone in mice and scale-up to humans: a semi-mechanistic model incorporating DNA and protein binding. | 2012 Jun |
1 |
| 16 |
20535833 | Effects of the isoflavonoid biochanin A on the transport of mitoxantrone in vitro and in vivo. | 2010 Jul |
3 |
| 17 |
19333870 | Relevance of multidrug resistance in the age of targeted therapy. | 2009 Mar |
4 |
| 18 |
19423841 | Dynamic assessment of mitoxantrone resistance and modulation of multidrug resistance by valspodar (PSC833) in multidrug resistance human cancer cells. | 2009 Aug |
3 |
| 19 |
18718123 | Presence or absence of a gallate moiety on catechins affects their cellular transport. | 2008 Sep |
2 |
| 20 |
18829547 | Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2. | 2008 Oct 1 |
1 |
| 21 |
17031644 | Differential effects of the immunosuppressive agents cyclosporin A, tacrolimus and sirolimus on drug transport by multidrug resistance proteins. | 2007 Jul |
2 |
| 22 |
17900739 | Effect of excipients on breast cancer resistance protein substrate uptake activity. | 2007 Dec 4 |
2 |
| 23 |
18006847 | Erlotinib (Tarceva, OSI-774) antagonizes ATP-binding cassette subfamily B member 1 and ATP-binding cassette subfamily G member 2-mediated drug resistance. | 2007 Nov 15 |
1 |
| 24 |
16434618 | Multidrug resistance protein 1 (MRP1, ABCC1) mediates resistance to mitoxantrone via glutathione-dependent drug efflux. | 2006 Apr |
6 |
| 25 |
16740770 | ABCB1 modulation does not circumvent drug extrusion from primitive leukemic progenitor cells and may preferentially target residual normal cells in acute myelogenous leukemia. | 2006 Jun 1 |
6 |
| 26 |
15788683 | Cyclosporin A is a broad-spectrum multidrug resistance modulator. | 2005 Mar 15 |
1 |
| 27 |
15920909 | Induction of the ABC-transporters Mdr1/P-gp (Abcb1), mrpl (Abcc1), and bcrp (Abcg2) during establishment of multidrug resistance following exposure to mitoxantrone. | 2005 Apr |
6 |
| 28 |
15167906 | A phase II study of intensive chemotherapy with fludarabine, cytarabine, and mitoxantrone in P glycoprotein-negative high-risk myelodysplastic syndromes. | 2004 |
1 |
| 29 |
12687290 | Ketotifen reverses MDR1-mediated multidrug resistance in human breast cancer cells in vitro and alleviates cardiotoxicity induced by doxorubicin in vivo. | 2003 May |
1 |
| 30 |
11809686 | In vivo analysis of human multidrug resistance protein 1 (MRP1) activity using transient expression of fluorescently tagged MRP1. | 2002 Jan 15 |
1 |
| 31 |
12136248 | Multiple mechanisms confer different drug-resistant phenotypes in pancreatic carcinoma cells. | 2002 Jul |
1 |
| 32 |
12415630 | P-glycoprotein expression by cancer cells affects cell cytotoxicity and cell-cycle perturbations induced by six chemotherapeutic drugs. | 2002 May-Jun |
1 |
| 33 |
9933132 | Effect on cell kill of addition of multidrug resistance modifiers cyclosporin A and PSC 833 to cytotoxic agents in chronic lymphocytic leukaemia. | 1999 Jan |
1 |
| 34 |
10070941 | Atypical multidrug resistance: breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines. | 1999 Mar 3 |
1 |
| 35 |
10342576 | Cellular uptake and antiproliferative effects of therapeutic concentrations of idarubicin or daunorubicin and their alcohol metabolites, with or without cyclosporin A, in MDR1+ human leukemic cells. | 1999 May |
2 |
| 36 |
9615755 | Chromosome mediated gene transfer of drug resistance to mitoxantrone. | 1998 Mar-Apr |
1 |
| 37 |
9685354 | Coordinated action of glutathione S-transferases (GSTs) and multidrug resistance protein 1 (MRP1) in antineoplastic drug detoxification. Mechanism of GST A1-1- and MRP1-associated resistance to chlorambucil in MCF7 breast carcinoma cells. | 1998 Aug 7 |
1 |
| 38 |
9180292 | The combined effects of IL-3 and PSC 833 on daunorubicin- and mitoxantrone cytotoxicity in two growth factor-dependent leukemic cell lines. | 1997 May |
2 |
| 39 |
9447822 | Cellular pharmacology of mitoxantrone in p-glycoprotein-positive and -negative human myeloid leukemic cell lines. | 1997 Dec |
4 |
| 40 |
7664272 | Cross-resistance to camptothecin analogues in a mitoxantrone-resistant human breast carcinoma cell line is not due to DNA topoisomerase I alterations. | 1995 Sep 15 |
1 |
| 41 |
7906380 | Cytosine arabinoside and mitoxantrone treatment of relapsed or refractory childhood leukemia: initial response and relationship to multidrug resistance gene 1. | 1994 |
1 |
| 42 |
8185674 | Analysis of MRP mRNA in mitoxantrone-selected, multidrug-resistant human tumor cells. | 1994 Apr 29 |
1 |
| 43 |
1350249 | In vitro effect of P-glycoprotein (P-gp) modulators on drug sensitivity of leukemic progenitors (CFU-L) in acute myelogenous leukemia (AML). | 1992 Jun |
2 |
| 44 |
2894893 | Cytogenetic and phenotypic analysis of a human colon carcinoma cell line resistant to mitoxantrone. | 1988 Apr 1 |
1 |