| 51 |
26531821 | ABCB1 gene variants, digoxin and risk of sudden cardiac death in a general population. | 2015 Dec |
7 |
| 52 |
26701637 | [Reversal of adriamycin resistance by digoxin in human breast cancer cell line MCF-7/adriamycin and its mechanism]. | 2015 Dec 25 |
3 |
| 53 |
27137717 | Effect of lapatinib on oral digoxin absorption in patients. | 2015 Nov |
1 |
| 54 |
24166743 | Suitability of digoxin as a P-glycoprotein probe: implications of other transporters on sensitivity and specificity. | 2014 Jan |
4 |
| 55 |
24212378 | In vitro predictability of drug-drug interaction likelihood of P-glycoprotein-mediated efflux of dabigatran etexilate based on [I]2/IC50 threshold. | 2014 Feb |
1 |
| 56 |
24283665 | Physiologically based pharmacokinetic modelling and in vivo [I]/K(i) accurately predict P-glycoprotein-mediated drug-drug interactions with dabigatran etexilate. | 2014 Feb |
3 |
| 57 |
24362330 | Phorbol 12-myristate 13-acetate inhibits P-glycoprotein-mediated efflux of digoxin in MDCKII-MDR1 and Caco-2 cell monolayer models. | 2014 Feb |
2 |
| 58 |
24687541 | Chronic Digoxin Toxicity Precipitated by Dronedarone. | 2014 Jul |
2 |
| 59 |
24887182 | Stereoselective property of 20(S)-protopanaxadiol ocotillol type epimers affects its absorption and also the inhibition of P-glycoprotein. | 2014 |
1 |
| 60 |
25034865 | Development, validation, and application of a novel 7-day Caco-2 cell culture system. | 2014 Sep-Oct |
1 |
| 61 |
25264938 | Convallatoxin: a new P-glycoprotein substrate. | 2014 Dec 5 |
8 |
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23073734 | Evaluation and prediction of potential drug-drug interactions of linagliptin using in vitro cell culture methods. | 2013 Jan |
1 |
| 63 |
23104431 | Interaction of digitalis-like compounds with p-glycoprotein. | 2013 Feb |
4 |
| 64 |
23372711 | Inhibition of P-glycoprotein by HIV protease inhibitors increases intracellular accumulation of berberine in murine and human macrophages. | 2013 |
1 |
| 65 |
23551115 | Potential role for human P-glycoprotein in the transport of lacosamide. | 2013 Jul |
1 |
| 66 |
23620485 | Variability in P-glycoprotein inhibitory potency (IC₅₀) using various in vitro experimental systems: implications for universal digoxin drug-drug interaction risk assessment decision criteria. | 2013 Jul |
1 |
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23620486 | Application of receiver operating characteristic analysis to refine the prediction of potential digoxin drug interactions. | 2013 Jul |
4 |
| 68 |
23686764 | Application of permeability-limited physiologically-based pharmacokinetic models: part II - prediction of P-glycoprotein mediated drug-drug interactions with digoxin. | 2013 Sep |
6 |
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23703021 | Application of permeability-limited physiologically-based pharmacokinetic models: part I-digoxin pharmacokinetics incorporating P-glycoprotein-mediated efflux. | 2013 Sep |
6 |
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23897240 | Acetaminophen inhibits intestinal p-glycoprotein transport activity. | 2013 Oct |
1 |
| 71 |
23976943 | Transport inhibition of digoxin using several common P-gp expressing cell lines is not necessarily reporting only on inhibitor binding to P-gp. | 2013 |
1 |
| 72 |
24002095 | Rilpivirine inhibits drug transporters ABCB1, SLC22A1, and SLC22A2 in vitro. | 2013 Nov |
2 |
| 73 |
24028619 | In-vitro evaluation of chronic alcohol effects on expression of drug-metabolizing and drug-transporting proteins. | 2013 Oct |
2 |
| 74 |
21257799 | Absence of pharmacokinetic interaction between roflumilast and digoxin in healthy adults. | 2012 Feb |
2 |
| 75 |
21343347 | Modeling the kinetics of digoxin absorption: enhancement by P-glycoprotein inhibition. | 2012 Mar |
4 |
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21477267 | Effect of vitamin D3 supplementation on the pharmacokinetics of digoxin--a pilot study. | 2012 Aug |
2 |
| 77 |
22181075 | The role of turmerones on curcumin transportation and P-glycoprotein activities in intestinal Caco-2 cells. | 2012 Mar |
2 |
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22300294 | Loxapine P-glycoprotein interactions in vitro. | 2012 Mar |
1 |
| 79 |
22411726 | Intestinal transport of pure diester-type alkaloids from an aconite extract across the Caco-2 cell monolayer model. | 2012 May |
2 |
| 80 |
22418036 | Human small intestinal and colonic tissue mounted in the Ussing chamber as a tool for characterizing the intestinal absorption of drugs. | 2012 Aug 15 |
2 |
| 81 |
22764293 | Potential P-glycoprotein-mediated drug-drug interactions of antimalarial agents in Caco-2 cells. | 2012 Jul |
1 |
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23023659 | Psychotropic drug-drug interactions involving P-glycoprotein. | 2012 Nov |
1 |
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23064285 | P-glycoprotein mediated efflux in Caco-2 cell monolayers: the influence of herbals on digoxin transport. | 2012 Dec 18 |
7 |
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21075975 | The utility of in vitro data in making accurate predictions of human P-glycoprotein-mediated drug-drug interactions: a case study for AZD5672. | 2011 Feb |
2 |
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21103977 | In vivo probes of drug transport: commonly used probe drugs to assess function of intestinal P-glycoprotein (ABCB1) in humans. | 2011 |
1 |
| 86 |
21287651 | Different transport activity of human triallelic MDR1 893Ala/Ser/Thr variant and its association with herb extracts. | 2011 Aug |
1 |
| 87 |
21311904 | Post-mortem ABCB1 genotyping reveals an elevated toxicity for female digoxin users. | 2011 Mar |
4 |
| 88 |
21488121 | Ultrafast mass spectrometry based bioanalytical method for digoxin supporting an in vitro P-glycoprotein (P-gp) inhibition screen. | 2011 May 15 |
3 |
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21657832 | Calcein assay: a high-throughput method to assess P-gp inhibition. | 2011 Aug |
1 |
| 90 |
21849517 | Digoxin is not a substrate for organic anion-transporting polypeptide transporters OATP1A2, OATP1B1, OATP1B3, and OATP2B1 but is a substrate for a sodium-dependent transporter expressed in HEK293 cells. | 2011 Nov |
3 |
| 91 |
19631272 | Xenopus laevis oocytes expressing human P-glycoprotein: probing trans- and cis-inhibitory effects on [3H]vinblastine and [3H]digoxin efflux. | 2010 Jan |
3 |
| 92 |
19914261 | Interaction of angiotensin II type 1 receptor blockers with P-gp substrates in Caco-2 cells and hMDR1-expressing membranes. | 2010 Jan 2 |
5 |
| 93 |
20197013 | Effect of saquinavir/ritonavir on P-glycoprotein activity in healthy volunteers using digoxin as a probe. | 2010 Mar |
1 |
| 94 |
20214407 | Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation. | 2010 Apr |
1 |
| 95 |
20397967 | P-glycoprotein related drug interactions: clinical importance and a consideration of disease states. | 2010 May |
1 |
| 96 |
20472816 | Clinical pharmacology of dronedarone: implications for the therapy of atrial fibrillation. | 2010 Dec |
3 |
| 97 |
20724802 | Inhibition of P-glycoprotein-mediated efflux of digoxin and its metabolites by macrolide antibiotics. | 2010 |
4 |
| 98 |
20844484 | The impact of thyroid disease on the regulation, expression, and function of ABCB1 (MDR1/P glycoprotein) and consequences for the disposition of digoxin. | 2010 Nov |
1 |
| 99 |
21041912 | Do activities of cytochrome P450 (CYP)3A, CYP2D6 and P-glycoprotein differ between healthy volunteers and HIV-infected patients? | 2010 |
1 |
| 100 |
21104926 | Tumor necrosis factor alpha increases P-glycoprotein expression in a BME-UV in vitro model of mammary epithelial cells. | 2010 Nov |
1 |