valspodar

ATP binding cassette subfamily B member 1 ; Homo sapiens







47 Article(s)
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1 32706283 P-Glycoprotein-Mediated Efflux Using a Rapidly Maturing Caco2 Clone (CLEFF4) in Only 5 Days without Requiring Modified Growth Medium. 2021 Jan 1
2 34066059 Upregulation of Chemoresistance by Mg2+ Deficiency through Elevation of ATP Binding Cassette Subfamily B Member 1 Expression in Human Lung Adenocarcinoma A549 Cells. 2021 May 12 1
3 32275773 P-Glycoprotein Inhibition Exacerbates Paclitaxel Neurotoxicity in Neurons and Patients With Cancer. 2020 Sep 1
4 32710919 Boosting drug bioavailability in men but not women through the action of an excipient. 2020 Sep 25 1
5 27926506 Disruption of the association between drug transporter and actin cytoskeleton abolishes drug resistance in hypertrophic scar. 2017 Jan 10 1
6 27783718 Up-regulation of ATP-binding cassette transporters in the THP-1 human macrophage cell line by the antichagasic benznidazole. 2016 Nov 2
7 25597754 The FLT3 and PDGFR inhibitor crenolanib is a substrate of the multidrug resistance protein ABCB1 but does not inhibit transport function at pharmacologically relevant concentrations. 2015 Apr 1
8 24700236 PARP Inhibitors as P-glyoprotein Substrates. 2014 Jun 1
9 22118813 ABCB1/MDR1 contributes to the anticancer drug-resistant phenotype of IPH-926 human lobular breast cancer cells. 2012 Feb 28 2
10 21318225 Accumulation of lactosylceramide and overexpression of a PSC833-resistant P-glycoprotein in multidrug-resistant human sarcoma cells. 2011 Apr 1
11 24309308 Role of p-glycoprotein expression and function in cystinotic renal proximal tubular cells. 2011 Oct 27 1
12 19188390 P-glycoprotein-mediated transport of moxifloxacin in a Calu-3 lung epithelial cell model. 2009 Apr 1
13 19423841 Dynamic assessment of mitoxantrone resistance and modulation of multidrug resistance by valspodar (PSC833) in multidrug resistance human cancer cells. 2009 Aug 4
14 17947497 Quantitation of doxorubicin uptake, efflux, and modulation of multidrug resistance (MDR) in MDR human cancer cells. 2008 Jan 1
15 18396325 Teasing apart activities of different types of ABC efflux pumps in bivalve gills using the concepts of independent action and concentration addition. 2008 Jul 1
16 15993035 Development of multidrug resistance type I P-glycoprotein function during in vitro maturation of porcine oocyte. 2006 Jan 1
17 16223781 Up-regulation of MDR1 and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells. 2006 Feb 15 1
18 16299163 Demonstration of docosahexaenoic acid as a bioavailability enhancer for CYP3A substrates: in vitro and in vivo evidence using cyclosporin in rats. 2006 Feb 2
19 16671962 Characterization of beta-adrenoceptor antagonists as substrates and inhibitors of the drug transporter P-glycoprotein. 2006 Jun 1
20 15788683 Cyclosporin A is a broad-spectrum multidrug resistance modulator. 2005 Mar 15 1
21 21783614 Diazinon cytotoxicity and transfer in Caco-2 cells: Effect of long-term exposure to the pesticide. 2005 Sep 2
22 15244080 pH dependent uptake of loperamide across the gastrointestinal tract: an in vitro study. 2004 May 1
23 15322734 Characterisation of cerivastatin as a P-glycoprotein substrate: studies in P-glycoprotein-expressing cell monolayers and mdr1a/b knock-out mice. 2004 Aug 1
24 15358539 Transport of somatostatin and substance P by human P-glycoprotein. 2004 Sep 10 1
25 15384974 The expression of P-glycoprotein in AML cells with FLT3 internal tandem duplications is associated with reduced apoptosis in response to FLT3 inhibitors. 2004 Oct 3
26 15472518 Identification of budesonide and prednisone as substrates of the intestinal drug efflux pump P-glycoprotein. 2004 Sep 2
27 12822513 Combined treatment of Bcl-2 antisense oligodeoxynucleotides (G3139), p-glycoprotein inhibitor (PSC833), and sterically stabilized liposomal doxorubicin suppresses growth of drug-resistant growth of drug-resistant breast cancer in severely combined immunodeficient mice. 2003 Mar-Apr 1
28 14641819 Modulation of resistance to idarubicin by the cyclosporin PSC 833 (valspodar) in multidrug-resistant cells. 2003 May-Jun 1
29 12152989 P-glycoprotein in acute myeloid leukaemia: therapeutic implications of its association with both a multidrug-resistant and an apoptosis-resistant phenotype. 2002 Jun 1
30 11123865 Overcoming drug resistance in ovarian carcinoma. 2001 Jan 1
31 11284449 P-glycoprotein-mediated transport of digitoxin, alpha-methyldigoxin and beta-acetyldigoxin. 2001 Mar 4
32 11408492 Phase II study of paclitaxel and valspodar (PSC 833) in refractory ovarian carcinoma: a gynecologic oncology group study. 2001 Jun 15 1
33 11566278 Effect of meta-tetra(hydroxyphenyl)chlorin (mTHPC)-mediated photodynamic therapy on sensitive and multidrug-resistant human breast cancer cells. 2001 Sep 15 1
34 11676863 Intracellular levels of two cyclosporin derivatives valspodar (PSC 833) and cyclosporin a closely associated with multidrug resistance-modulating activity in sublines of human colorectal adenocarcinoma HCT-15. 2001 Oct 1
35 10636889 Up-regulation of multidrug resistance P-glycoprotein via nuclear factor-kappaB activation protects kidney proximal tubule cells from cadmium- and reactive oxygen species-induced apoptosis. 2000 Jan 21 4
36 10784624 P-Glycoprotein inhibitor valspodar (PSC 833) increases the intracellular concentrations of daunorubicin in vivo in patients with P-glycoprotein-positive acute myeloid leukemia. 2000 May 3
37 10832593 Role of specific apoptotic pathways in the restoration of paclitaxel-induced apoptosis by valspodar in doxorubicin-resistant MCF-7 breast cancer cells. 2000 Feb 1
38 10837354 Role of multidrug resistance P-glycoprotein in the secretion of aldosterone by human adrenal NCI-H295 cells. 2000 Jun 1
39 10955805 P-glycoprotein and multidrug resistance protein activities in relation to treatment outcome in acute myeloid leukemia. 2000 Aug 1
40 10997946 Selective inhibition of human cytochrome P450 3A4 by N-[2(R)-hydroxy-1(S)-indanyl]-5-[2(S)-(1, 1-dimethylethylaminocarbonyl)-4-[(furo[2, 3-b]pyridin-5-yl)methyl]piperazin-1-yl]-4(S)-hydroxy-2(R)-phenylmethy lpentanamide and P-glycoprotein by valspodar in gene transfectant systems. 2000 Oct 1
41 10368654 Combinations of P-glycoprotein blockers, verapamil, PSC833, and cremophor act differently on the multidrug resistance associated protein (MRP) and on P-glycoprotein (Pgp). 1999 Mar-Apr 2
42 9530286 HIV-1 protease inhibitors are substrates for the MDR1 multidrug transporter. 1998 Mar 17 1
43 9914792 Inhibitory effects of a cyclosporin derivative, SDZ PSC 833, on transport of doxorubicin and vinblastine via human P-glycoprotein. 1998 Nov 7
44 9038218 Multidrug-resistant human sarcoma cells with a mutant P-glycoprotein, altered phenotype, and resistance to cyclosporins. 1997 Feb 28 1
45 9205006 Assays for the analysis of P-glycoprotein in acute myeloid leukemia and CD34 subsets of AML blasts. 1997 Jul 1
46 8616825 Rhodamine 123-efflux from hematopoietic subpopulations and leukaemic blast populations marked by PerCP-conjugated monoclonal antibodies. 1996 Feb 6 1
47 7559918 Inhibition of cell-mediated cytolysis and P-glycoprotein function in natural killer cells by verapamil isomers and cyclosporine A analogs. 1995 May 1