Cholesterol

⇄

ATP binding cassette subfamily B member 1 ; Homo sapiens







91 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
51 18539442 P-glycoprotein inhibition by membrane cholesterol modulation. 2008 Aug 7 3
52 19049391 Interaction of the P-glycoprotein multidrug efflux pump with cholesterol: effects on ATPase activity, drug binding and transport. 2008 Dec 23 14
53 17029589 Modulation of drug-stimulated ATPase activity of human MDR1/P-glycoprotein by cholesterol. 2007 Jan 15 9
54 17223079 Cholesterol: Coupling between membrane microenvironment and ABC transporter activity. 2007 Mar 2 2
55 17336270 Multidrug resistance protein 1 is not associated to detergent-resistant membranes. 2007 Apr 20 3
56 17497080 P-glycoprotein in proteoliposomes with low residual detergent: the effects of cholesterol. 2007 Nov 6
57 17608770 Mechanism of multidrug recognition by MDR1/ABCB1. 2007 Sep 4
58 17652262 Localization of the human breast cancer resistance protein (BCRP/ABCG2) in lipid rafts/caveolae and modulation of its activity by cholesterol in vitro. 2007 Oct 1
59 17653693 Plasma LDL cholesterol has no impact on P-glycoprotein (MDR1/ABCB1) activity in human peripheral blood mononuclear cells. 2007 Oct 6
60 17901905 Reversal of P-glycoprotein-mediated multidrug resistance by cholesterol derived from low density lipoprotein in a vinblastine-resistant human lymphoblastic leukemia cell line. 2007 Oct 2
61 17923246 P-glycoprotein is downregulated in KG1a-primitive leukemia cells by LDL cholesterol deprivation and by HMG-CoA reductase inhibitors. 2007 Dec 3
62 17955353 Cholesterol fill-in model: mechanism for substrate recognition by ABC proteins. 2007 Dec 6
63 16513445 Intestinal expression of P-glycoprotein (ABCB1), multidrug resistance associated protein 2 (ABCC2), and uridine diphosphate-glucuronosyltransferase 1A1 predicts the disposition and modulates the effects of the cholesterol absorption inhibitor ezetimibe in humans. 2006 Mar 2
64 16885132 Does p-glycoprotein play a role in gastrointestinal absorption and cellular transport of dietary cholesterol? 2006 Jul 3
65 16996216 Down-regulation of ABCB1 transporter by atorvastatin in a human hepatoma cell line and in human peripheral blood mononuclear cells. 2006 Dec 3
66 15693753 Multidrug-resistant cancer cells contain two populations of P-glycoprotein with differently stimulated P-gp ATPase activities: evidence from atomic force microscopy and biochemical analysis. 2005 Jun 1 6
67 15718846 The efavirenz-induced increase in HDL-cholesterol is influenced by the multidrug resistance gene 1 C3435T polymorphism. 2005 Feb 18 1
68 15766280 Control of P-glycoprotein activity by membrane cholesterol amounts and their relation to multidrug resistance in human CEM leukemia cells. 2005 Mar 22 9
69 16138223 High baseline serum total and LDL cholesterol levels are associated with MDR1 haplotypes in Brazilian hypercholesterolemic individuals of European descent. 2005 Sep 2
70 16176266 P-Glycoprotein is localized in intermediate-density membrane microdomains distinct from classical lipid rafts and caveolar domains. 2005 Oct 3
71 15001473 An anti-CD19 antibody inhibits the interaction between P-glycoprotein (P-gp) and CD19, causes P-gp to translocate out of lipid rafts, and chemosensitizes a multidrug-resistant (MDR) lymphoma cell line. 2004 Jul 1 1
72 15033457 Cholesterol modulates P-glycoprotein activity in human peripheral blood mononuclear cells. 2004 Apr 9 4
73 15139519 Contribution of cholesterol and phospholipids to inhibitory effect of dimethyl-beta-cyclodextrin on efflux function of P-glycoprotein and multidrug resistance-associated protein 2 in vinblastine-resistant Caco-2 cell monolayers. 2004 Apr 1
74 15308763 Modulation of cellular cholesterol alters P-glycoprotein activity in multidrug-resistant cells. 2004 Nov 9
75 12586368 Involvement of cholesterol in the inhibitory effect of dimethyl-beta-cyclodextrin on P-glycoprotein and MRP2 function in Caco-2 cells. 2003 Feb 11 2
76 12925201 Adenosine triphosphate binding cassette (ABC) transporters are expressed and regulated during terminal keratinocyte differentiation: a potential role for ABCA7 in epidermal lipid reorganization. 2003 Sep 1
77 12110376 Elevated uptake of low density lipoprotein by drug resistant human leukemic cell lines. 2002 Jun 15 1
78 12145328 The multidrug transporter, P-glycoprotein, actively mediates cholesterol redistribution in the cell membrane. 2002 Aug 6 11
79 11461099 Lipid metabolism and molecular changes in normal and atherosclerotic vessels. 2001 Jul 1
80 11718296 The importance of cholesterol in maintenance of P-glycoprotein activity and its membrane perturbing influence. 2001 Oct 4
81 10631102 Overexpression of MDR1 in an intestinal cell line results in increased cholesterol uptake from micelles. 2000 Jan 19 5
82 10811443 A role for P-glycoprotein in regulating cell death. 2000 Jun 2
83 10869171 Effects of cholesterol and enantiomeric cholesterol on P-glycoprotein localization and function in low-density membrane domains. 2000 Jul 4 11
84 11027568 Cholesterol interaction with the daunorubicin binding site of P-glycoprotein. 2000 Oct 5 11
85 11118294 Multidrug resistance P-glycoprotein is not involved in cholesterol esterification. 2000 Dec 20 1
86 10066752 Multidrug resistance (MDR1) P-glycoprotein enhances esterification of plasma membrane cholesterol. 1999 Mar 12 3
87 10371303 Correlation between cholesterol esterification, MDR1 gene expression and rate of cell proliferation in CEM and MOLT4 cell lines. 1999 Feb 2
88 10474039 MDR1 gene expression in normal and atherosclerotic human arteries(1). 1999 Jul-Aug 5
89 9507994 Transport of cholesterol from the endoplasmic reticulum to the plasma membrane is constitutive in CaCo-2 cells and differs from the transport of plasma membrane cholesterol to the endoplasmic reticulum. 1998 Feb 2
90 19002782 Molecular analysis of the multidrug transporter, P-glycoprotein. 1998 Sep 1
91 7595077 Esterification of plasma membrane cholesterol and triacylglycerol-rich lipoprotein secretion in CaCo-2 cells: possible role of p-glycoprotein. 1995 Jul 1