| 1 |
31481446 | Anti-HIV and Anti-Hepatitis C Virus Drugs Inhibit P-Glycoprotein Efflux Activity in Caco-2 Cells and Precision-Cut Rat and Human Intestinal Slices. | 2019 Nov |
2 |
| 2 |
26026069 | α-Tocopherols modify the membrane dipole potential leading to modulation of ligand binding by P-glycoprotein. | 2015 Aug |
3 |
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23381882 | Mechanisms of pharmacokinetic enhancement between ritonavir and saquinavir; micro/small dosing tests using midazolam (CYP3A4), fexofenadine (p-glycoprotein), and pravastatin (OATP1B1) as probe drugs. | 2013 Jun |
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22104402 | Expression of P-glycoprotein and multidrug resistance-associated protein on human brain-microvascular endothelial cells with electromagnetic stimulation. | 2012 Mar 1 |
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| 5 |
22136805 | Modulation of efflux proteins by electromagnetic field for delivering azidothymidine and saquinavir into the brain. | 2012 Mar 1 |
2 |
| 6 |
20197013 | Effect of saquinavir/ritonavir on P-glycoprotein activity in healthy volunteers using digoxin as a probe. | 2010 Mar |
4 |
| 7 |
18480151 | Influence of adenosine triphosphate and ABCB1 (MDR1) genotype on the P-glycoprotein-dependent transfer of saquinavir in the dually perfused human placenta. | 2008 Jan |
4 |
| 8 |
17361121 | The effect of ABCB1 polymorphism on the pharmacokinetics of saquinavir alone and in combination with ritonavir. | 2007 Oct |
2 |
| 9 |
17510066 | Interindividual variability in the effect of atazanavir and saquinavir on the expression of lymphocyte P-glycoprotein. | 2007 Jul |
2 |
| 10 |
17591027 | Synergistic inhibition of protease-inhibitor-resistant HIV type 1 by saquinavir in combination with atazanavir or lopinavir. | 2007 |
2 |
| 11 |
16084847 | Functional role of P-glycoprotein in the human blood-placental barrier. | 2005 Aug |
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| 12 |
16137847 | Evasion of P-gp mediated cellular efflux and permeability enhancement of HIV-protease inhibitor saquinavir by prodrug modification. | 2005 Oct 13 |
2 |
| 13 |
16184031 | MDR1 G1199A polymorphism alters permeability of HIV protease inhibitors across P-glycoprotein-expressing epithelial cells. | 2005 Oct 14 |
1 |
| 14 |
16284458 | Modulation of the intracellular accumulation of saquinavir in peripheral blood mononuclear cells by inhibitors of MRP1, MRP2, P-gp and BCRP. | 2005 Dec 2 |
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| 15 |
14718607 | Contributions of CYP3A4, P-glycoprotein, and serum protein binding to the intestinal first-pass extraction of saquinavir. | 2004 Mar |
4 |
| 16 |
15553233 | Comparative effects on intestinal absorption in situ by P-glycoprotein-modifying HIV protease inhibitors. | 2004 Oct |
1 |
| 17 |
15646074 | P-glycoprotein expression affects the intracellular concentration and antiviral activity of the protease inhibitor saquinavir in a T cell line. | 2004 Apr |
2 |
| 18 |
12714803 | Differential effect of HIV-1 protease inhibitors on P-glycoprotein function in multidrug-resistant variants of the human CD4+ T lymphoblastoid CEM cell line. | 2003 May |
2 |
| 19 |
14525546 | Saquinavir induces stable and functional expression of the multidrug transporter P-glycoprotein in human CD4 T-lymphoblastoid CEMrev cells. | 2003 Oct |
12 |
| 20 |
12047481 | Dose-dependent increase of saquinavir bioavailability by the pharmaceutic aid cremophor EL. | 2002 Jun |
2 |
| 21 |
12356805 | P-glycoprotein and MRP1 expression and reduced ritonavir and saquinavir accumulation in HIV-infected individuals. | 2002 Oct |
3 |
| 22 |
11468419 | HIV-protease inhibitors contribute to P-glycoprotein efflux function defect in peripheral blood lymphocytes from HIV-positive patients receiving HAART. | 2001 Aug 1 |
1 |
| 23 |
10509562 | Modulation of P-glycoprotein function in human lymphocytes and Caco-2 cell monolayers by HIV-1 protease inhibitors. | 1999 Sep 10 |
5 |
| 24 |
11230802 | HIV protease inhibitor ritonavir: a more potent inhibitor of P-glycoprotein than the cyclosporine analog SDZ PSC 833. | 1999 May 15 |
3 |
| 25 |
9732409 | Saquinavir, an HIV protease inhibitor, is transported by P-glycoprotein. | 1998 Sep |
8 |
| 26 |
9803961 | Interaction of anti-HIV protease inhibitors with the multidrug transporter P-glycoprotein (P-gp) in human cultured cells. | 1998 Nov 1 |
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| 27 |
9835508 | Human immunodeficiency virus protease inhibitors serve as substrates for multidrug transporter proteins MDR1 and MRP1 but retain antiviral efficacy in cell lines expressing these transporters. | 1998 Dec |
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