| 1 |
33649523 | Single nucleotide polymorphisms to predict taxanes toxicities and effectiveness in cancer patients. | 2021 Aug |
1 |
| 2 |
34126072 | CMP25, a synthetic new agent, targets multidrug resistance-associated protein 7 (MRP7/ABCC10). | 2021 Aug |
1 |
| 3 |
32749138 | Current Development of Oral Taxane Formulations: A Review. | 2020 |
1 |
| 4 |
31075528 | Overexpressed ABCB1 Induces Olaparib-Taxane Cross-Resistance in Advanced Prostate Cancer. | 2019 Jul |
3 |
| 5 |
31181726 | Synthesis and Cytotoxicity of 7,9-O-Linked Macrocyclic C-Seco Taxoids. | 2019 Jun 8 |
1 |
| 6 |
29441783 | Synthesis of a Next-Generation Taxoid by Rapid Methylation Amenable for 11C-Labeling. | 2018 Mar 2 |
2 |
| 7 |
29517223 | Taxol Analogues Exhibit Differential Effects on Photoaffinity Labeling of β-Tubulin and the Multidrug Resistance Associated P-Glycoprotein. | 2018 Mar 23 |
3 |
| 8 |
29625142 | Substituents at the C3' and C3'N positions are critical for taxanes to overcome acquired resistance of cancer cells to paclitaxel. | 2018 May 15 |
2 |
| 9 |
29675746 | Cabazitaxel is more active than first-generation taxanes in ABCB1(+) cell lines due to its reduced affinity for P-glycoprotein. | 2018 Jun |
2 |
| 10 |
29861877 | SNPs in predicting clinical efficacy and toxicity of chemotherapy: walking through the quicksand. | 2018 May 18 |
1 |
| 11 |
27868228 | Pharmacokinetic interaction between taxanes and amiodarone leading to severe toxicity. | 2017 Apr |
2 |
| 12 |
28476838 | Pharmacogenetic Approach to Toxicity in Breast Cancer Patients Treated with Taxanes. | 2017 May |
2 |
| 13 |
28624703 | Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by βIII-Tubulin and P-glycoprotein (P-gp) overexpressions. | 2017 Sep 8 |
2 |
| 14 |
28941201 | Synthesis and in vitro Biological Evaluation of Ferrocenyl Side-Chain-Functionalized Paclitaxel Derivatives. | 2017 Nov 22 |
1 |
| 15 |
27574448 | Polymorphism of CYP3A4 and ABCB1 genes increase the risk of neuropathy in breast cancer patients treated with paclitaxel and docetaxel. | 2016 |
1 |
| 16 |
27725879 | Targeting ABCB1-mediated tumor multidrug resistance by CRISPR/Cas9-based genome editing. | 2016 |
2 |
| 17 |
27727250 | Notch-1 Confers Chemoresistance in Lung Adenocarcinoma to Taxanes through AP-1/microRNA-451 Mediated Regulation of MDR-1. | 2016 Oct 11 |
1 |
| 18 |
28642838 | Adaptive pathways and emerging strategies overcoming treatment resistance in castration resistant prostate cancer. | 2016 Oct |
2 |
| 19 |
25685543 | P-glycoprotein inhibitors of natural origin as potential tumor chemo-sensitizers: A review. | 2015 Jan |
1 |
| 20 |
24332858 | The synthesis of novel taxoids for oral administration. | 2014 Jan 1 |
2 |
| 21 |
24447372 | Multiple mechanisms underlying acquired resistance to taxanes in selected docetaxel-resistant MCF-7 breast cancer cells. | 2014 Jan 22 |
1 |
| 22 |
24704000 | Assessment of clinical outcomes in breast cancer patients treated with taxanes: multi-analytical approach. | 2014 Jun 10 |
2 |
| 23 |
24344919 | Epigenetic regulation of MDR1 gene through post-translational histone modifications in prostate cancer. | 2013 Dec 17 |
2 |
| 24 |
21374643 | Overcoming tumor multidrug resistance using drugs able to evade P-glycoprotein or to exploit its expression. | 2012 Nov |
2 |
| 25 |
21618519 | Let-7 modulates acquired resistance of ovarian cancer to Taxanes via IMP-1-mediated stabilization of multidrug resistance 1. | 2012 Apr 15 |
1 |
| 26 |
22855252 | Transport, metabolism, cytotoxicity and effects of novel taxanes on the cell cycle in MDA-MB-435 and NCI/ADR-RES cells. | 2012 Oct |
2 |
| 27 |
21448449 | Cabazitaxel: a novel second-line treatment for metastatic castration-resistant prostate cancer. | 2011 Mar 10 |
2 |
| 28 |
21680190 | 2-Amino-4-methyl-5-phenylethyl substituted-7-N-benzyl-pyrrolo[2,3-d]pyrimidines as novel antitumor antimitotic agents that also reverse tumor resistance. | 2011 Jul 15 |
4 |
| 29 |
19401306 | Clinical significance of ABCB1 genotyping in oncology. | 2010 Mar |
3 |
| 30 |
20374029 | Pharmacogenetics in breast cancer: focus on hormone therapy, taxanes, trastuzumab and bevacizumab. | 2010 Apr |
1 |
| 31 |
20944127 | Two multidrug-resistance (ABCB1) gene polymorphisms as prognostic parameters in women with ovarian cancer. | 2010 Sep |
2 |
| 32 |
24900226 | From taxuspine x to structurally simplified taxanes with remarkable p-glycoprotein inhibitory activity. | 2010 Nov 11 |
4 |
| 33 |
19355888 | Tubulin: a target for antineoplastic drugs into the cancer cells but also in the peripheral nervous system. | 2009 |
1 |
| 34 |
19442049 | Multidrug resistance through the spectacle of P-glycoprotein. | 2009 May |
3 |
| 35 |
19470292 | Emerging significance of flavonoids as P-glycoprotein inhibitors in cancer chemotherapy. | 2009 |
1 |
| 36 |
18559268 | Optimization of taxane binding to microtubules: binding affinity dissection and incremental construction of a high-affinity analog of paclitaxel. | 2008 Jun |
1 |
| 37 |
17620438 | Inhibition of the mitogen-activated protein kinase pathway results in the down-regulation of P-glycoprotein. | 2007 Jul |
4 |
| 38 |
16382445 | Regional activation of chromosomal arm 7q with and without gene amplification in taxane-selected human ovarian cancer cell lines. | 2006 Apr |
3 |
| 39 |
16497442 | Taxanes in paediatric oncology: and now? | 2006 Apr |
1 |
| 40 |
16842217 | Pharmacological strategies for overcoming multidrug resistance. | 2006 Jul |
1 |
| 41 |
15060738 | Broad-spectrum modulation of ATP-binding cassette transport proteins by the taxane derivatives ortataxel (IDN-5109, BAY 59-8862) and tRA96023. | 2004 May |
2 |
| 42 |
15152938 | Structure-activity analysis of taxane-based broad-spectrum multidrug resistance modulators. | 2004 Mar-Apr |
1 |
| 43 |
15457126 | Ex vivo reversal of chemoresistance by tariquidar (XR9576). | 2004 Oct |
2 |
| 44 |
12548594 | A phase II trial of docetaxel and estramustine in patients with refractory metastatic breast carcinoma. | 2003 Feb 1 |
2 |
| 45 |
12711638 | Nonlinear accumulation in the brain of the new taxoid TXD258 following saturation of P-glycoprotein at the blood-brain barrier in mice and rats. | 2003 Apr |
2 |
| 46 |
14617793 | Taxane-based reversal agents modulate drug resistance mediated by P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein. | 2003 Nov |
1 |
| 47 |
14981994 | Chemotherapy with epirubicin and paclitaxel for breast cancer during pregnancy: case report and review of the literature. | 2003 Nov-Dec |
1 |
| 48 |
11801563 | Differences in therapeutic indexes of combination metronomic chemotherapy and an anti-VEGFR-2 antibody in multidrug-resistant human breast cancer xenografts. | 2002 Jan |
2 |
| 49 |
12016034 | [New taxanes and epothilone derivatives in clinical trials]. | 2002 Apr |
1 |
| 50 |
11466674 | Prediction of chemotherapeutic response by Technetium 99m--MIBI scintigraphy in breast carcinoma patients. | 2001 Jul 15 |
2 |