| 1 |
34403130 | Pharmacogenomics of statins: lipid response and other outcomes in Brazilian cohorts. | 2022 Feb |
1 |
| 2 |
33459228 | HMG-CoA Reductase Inhibitors (Statins) and their Drug Interactions Involving CYP Enzymes, P-glycoprotein and OATP Transporters-An Overview. | 2021 |
1 |
| 3 |
34162690 | Comparative Hepatic and Intestinal Efflux Transport of Statins. | 2021 Sep |
4 |
| 4 |
31574240 | Association of ABCB1 polymorphisms with lipid homeostasis and liver injury response to atorvastatin in the Chinese population. | 2020 Jan |
1 |
| 5 |
32275773 | P-Glycoprotein Inhibition Exacerbates Paclitaxel Neurotoxicity in Neurons and Patients With Cancer. | 2020 Sep |
1 |
| 6 |
31084979 | Drug-drug interactions involving CYP3A4 and p-glycoprotein in hospitalized elderly patients. | 2019 Jul |
1 |
| 7 |
31298164 | Association of SLCO1B1 and ABCB1 Genetic Variants with Atorvastatin-induced Myopathy in Patients with Acute Ischemic Stroke. | 2019 |
1 |
| 8 |
28833323 | Transporter genes ABCG2 rs2231142 and ABCB1 rs1128503 polymorphisms and atorvastatin response in Chilean subjects. | 2018 Feb |
2 |
| 9 |
27238935 | Association of ABCB1 (C3435T) and ABCC1 (G2012T) Polymorphisms with Clinical Response to Atorvastatin in Iranian Patients with Primary Hyperlipidemia. | 2017 Mar |
2 |
| 10 |
26857559 | A pharmacogenetic pilot study reveals MTHFR, DRD3, and MDR1 polymorphisms as biomarker candidates for slow atorvastatin metabolizers. | 2016 Feb 8 |
3 |
| 11 |
26932749 | Genetic determinants of lipid-lowering response to atorvastatin therapy in an Indian population. | 2016 Jun |
2 |
| 12 |
27296832 | ABCB1 polymorphism is associated with atorvastatin-induced liver injury in Japanese population. | 2016 Jun 13 |
5 |
| 13 |
27575876 | Atorvastatin attenuation of ABCB1 expression is mediated by microRNA miR-491-3p in Caco-2 cells. | 2016 Oct 10 |
5 |
| 14 |
24414406 | The role of Multidrug Resistance-1 (MDR1) variants in response to atorvastatin among Jordanians. | 2015 Mar |
5 |
| 15 |
24452746 | Effect of steady-state atorvastatin on the pharmacokinetics of a single dose of colchicine in healthy adults under fasted conditions. | 2014 Apr |
1 |
| 16 |
23361102 | Impact of OATP1B1, MDR1, and CYP3A4 expression in liver and intestine on interpatient pharmacokinetic variability of atorvastatin in obese subjects. | 2013 Mar |
1 |
| 17 |
23379020 | MDR1 and LPL genetic variants are associated with unfavorable outcome in stroke patients under atorvastatin treatment. | 2013 Jan |
1 |
| 18 |
23677857 | Do MDR1 and SLCO1B1 polymorphisms influence the therapeutic response to atorvastatin? A study on a cohort of Egyptian patients with hypercholesterolemia. | 2013 Oct |
2 |
| 19 |
23751277 | Atorvastatin treatment induces uptake and efflux transporters in human liver. | 2013 Sep |
2 |
| 20 |
23822632 | An integrated in vitro model for simultaneous assessment of drug uptake, metabolism, and efflux. | 2013 Aug 5 |
1 |
| 21 |
21820929 | [Specific considerations on the prescription and therapeutic interchange of statins]. | 2012 Mar-Apr |
1 |
| 22 |
22120734 | Identification of pharmacogenetic predictors of lipid-lowering response to atorvastatin in Chilean subjects with hypercholesterolemia. | 2012 Feb 18 |
1 |
| 23 |
22810051 | Genetic variation in MDR1, LPL and eNOS genes and the response to atorvastatin treatment in ischemic stroke. | 2012 Nov |
3 |
| 24 |
21392722 | The C3435T polymorphism in ABCB1 influences atorvastatin efficacy and muscle symptoms in a high-risk vascular cohort. | 2011 Mar-Apr |
4 |
| 25 |
21447733 | Use of transporter knockdown Caco-2 cells to investigate the in vitro efflux of statin drugs. | 2011 Jul |
1 |
| 26 |
19802823 | Influence of genetic variation in CYP3A4 and ABCB1 on dose decrease or switching during simvastatin and atorvastatin therapy. | 2010 Jan |
3 |
| 27 |
20040338 | Effects of SLCO1B1 and ABCB1 genotypes on the pharmacokinetics of atorvastatin and 2-hydroxyatorvastatin in healthy Korean subjects. | 2010 Jan |
3 |
| 28 |
20578904 | Common variants of HMGCR, CETP, APOAI, ABCB1, CYP3A4, and CYP7A1 genes as predictors of lipid-lowering response to atorvastatin therapy. | 2010 Oct |
2 |
| 29 |
21351272 | Differential interactions between statins and P-glycoprotein: implications for exploiting statins as anticancer agents. | 2010 Dec 15 |
1 |
| 30 |
18851956 | ABCB1 and ABCC1 expression in peripheral mononuclear cells is influenced by gene polymorphisms and atorvastatin treatment. | 2009 Jan 1 |
9 |
| 31 |
19280517 | Drug-drug interaction studies in preclinical species: should metabolite(s) kinetics be studied? | 2009 Mar |
2 |
| 32 |
19394420 | Decreased ABCB1 mRNA expression induced by atorvastatin results from enhanced mRNA degradation in HepG2 cells. | 2009 Jun 28 |
6 |
| 33 |
19543298 | The expression of efflux and uptake transporters are regulated by statins in Caco-2 and HepG2 cells. | 2009 Jul |
1 |
| 34 |
18193210 | Drug interaction between oral atorvastatin and verapamil in healthy subjects: effects of atorvastatin on the pharmacokinetics of verapamil and norverapamil. | 2008 May |
4 |
| 35 |
18661126 | Dual drug interactions via P-glycoprotein (P-gp)/ cytochrome P450 (CYP3A4) interplay: recent case study of oral atorvastatin and verapamil. | 2008 Nov |
2 |
| 36 |
18703021 | Induction of P-glycoprotein expression and function in human intestinal epithelial cells (T84). | 2008 Oct 1 |
3 |
| 37 |
19238649 | ABCB1 haplotypes differentially affect the pharmacokinetics of the acid and lactone forms of simvastatin and atorvastatin. | 2008 Oct |
3 |
| 38 |
16996216 | Down-regulation of ABCB1 transporter by atorvastatin in a human hepatoma cell line and in human peripheral blood mononuclear cells. | 2006 Dec |
9 |
| 39 |
16103896 | An association study of 43 SNPs in 16 candidate genes with atorvastatin response. | 2005 |
1 |
| 40 |
15081455 | Polymorphisms in the multidrug resistance-1 (MDR1) gene influence the response to atorvastatin treatment in a gender-specific manner. | 2004 Apr 15 |
3 |
| 41 |
15497697 | Interactions of human P-glycoprotein with simvastatin, simvastatin acid, and atorvastatin. | 2004 Sep |
8 |
| 42 |
12773066 | Rhabdomyolysis causing AV blockade due to possible atorvastatin, esomeprazole, and clarithromycin interaction. | 2003 Jun |
3 |
| 43 |
10631627 | Atorvastatin coadministration may increase digoxin concentrations by inhibition of intestinal P-glycoprotein-mediated secretion. | 2000 Jan |
3 |
| 44 |
10751037 | Atorvastatin transport in the Caco-2 cell model: contributions of P-glycoprotein and the proton-monocarboxylic acid co-transporter. | 2000 Feb |
5 |