Docetaxel

ATP binding cassette subfamily B member 1 ; Homo sapiens







123 Article(s)
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51 25648089 Genetic Variations of Drug Transporters Can Influence on Drug Response in Patients Treated with Docetaxel Chemotherapy. 2015 Jul 4
52 25760729 DNA methylation of DKK3 modulates docetaxel chemoresistance in human nonsmall cell lung cancer cell. 2015 Mar 1
53 25932627 Validation of a P-Glycoprotein (P-gp) Humanized Mouse Model by Integrating Selective Absolute Quantification of Human MDR1, Mouse Mdr1a and Mdr1b Protein Expressions with In Vivo Functional Analysis for Blood-Brain Barrier Transport. 2015 1
54 25995342 Antiandrogens Inhibit ABCB1 Efflux and ATPase Activity and Reverse Docetaxel Resistance in Advanced Prostate Cancer. 2015 Sep 15 1
55 26027763 Serum exosomal P-glycoprotein is a potential marker to diagnose docetaxel resistance and select a taxoid for patients with prostate cancer. 2015 Sep 11
56 26057062 Prostate cancer: Antiandrogens reverse docetaxel resistance via ABCB1 inhibition. 2015 Jul 1
57 26154614 Initial testing (stage 1) of the anti-microtubule agents cabazitaxel and docetaxel, by the pediatric preclinical testing program. 2015 Nov 1
58 26506423 Bis-cyclopropane analog of disorazole C1 is a microtubule-destabilizing agent active in ABCB1-overexpressing human colon cancer cells. 2015 Dec 1 1
59 24219005 Phase II and pharmacological study of oral docetaxel plus cyclosporin A in anthracycline pre-treated metastatic breast cancer. 2014 May 2
60 24883107 The role of cabazitaxel in the treatment of metastatic castration-resistant prostate cancer. 2014 Jun 1
61 21795074 Combination of docetaxel and vandetanib in docetaxel-sensitive or resistant PC3 cell line. 2013 Aug 2
62 22426195 Increased brain uptake of docetaxel and ketoconazole loaded folate-grafted solid lipid nanoparticles. 2013 Jan 4
63 23053273 Changing the expression vector of multidrug resistance genes is related to neoadjuvant chemotherapy response. 2013 Jan 1
64 23364915 Chemotherapy-induced immunogenic modulation of tumor cells enhances killing by cytotoxic T lymphocytes and is distinct from immunogenic cell death. 2013 Aug 1 2
65 23666532 Influence of ABCB1 polymorphisms and docetaxel pharmacokinetics on pathological response to neoadjuvant chemotherapy in breast cancer patients. 2013 Jun 1
66 23683834 20(S)-Protopanaxadiol (PPD) analogues chemosensitize multidrug-resistant cancer cells to clinical anticancer drugs. 2013 Jul 15 2
67 23861346 Inhibition of ABCB1 expression overcomes acquired docetaxel resistance in prostate cancer. 2013 Sep 9
68 23928571 Coadministration of lapatinib increases exposure to docetaxel but not doxorubicin in the small intestine of mice. 2013 Oct 1
69 21505085 From mouse to man: predictions of human pharmacokinetics of orally administered docetaxel from preclinical studies. 2012 Mar 2
70 21720762 Two different docetaxel resistant MCF-7 sublines exhibited different gene expression pattern. 2012 Apr 1
71 22271208 Prospective evaluation of the drug-metabolizing enzyme polymorphisms and toxicity profile of docetaxel in Korean patients with operable lymph node-positive breast cancer receiving adjuvant chemotherapy. 2012 May 1
72 22294184 The association of statins and taxanes: an efficient combination trigger of cancer cell apoptosis. 2012 Feb 14 2
73 22445862 Docetaxel and 5-fluorouracil induce human p53 tumor suppressor gene transcription via a short sequence at core promoter element. 2012 Aug 1
74 22572929 FG020326 sensitized multidrug resistant cancer cells to docetaxel-mediated apoptosis via enhancement of caspases activation. 2012 May 9 6
75 23251413 Docetaxel-resistance in prostate cancer: evaluating associated phenotypic changes and potential for resistance transfer via exosomes. 2012 2
76 23493035 Different Expression of Extracellular Signal-Regulated Kinases (ERK) 1/2 and Phospho-Erk Proteins in MBA-MB-231 and MCF-7 Cells after Chemotherapy with Doxorubicin or Docetaxel. 2012 Jan 2
77 21262849 Ixabepilone, a novel microtubule-targeting agent for breast cancer, is a substrate for P-glycoprotein (P-gp/MDR1/ABCB1) but not breast cancer resistance protein (BCRP/ABCG2). 2011 May 1
78 21448449 Cabazitaxel: a novel second-line treatment for metastatic castration-resistant prostate cancer. 2011 Mar 10 4
79 21468756 The effects of CYP3A4, CYP3A5, ABCB1, ABCC2, ABCG2 and SLCO1B3 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of docetaxel in nasopharyngeal carcinoma patients. 2011 Jun 2
80 21695098 Clinical development of cabazitaxel for the treatment of castration-resistant prostate cancer. 2011 1
81 22011009 Resveratrol enhances the cytotoxic profile of docetaxel and doxorubicin in solid tumour cell lines in vitro. 2011 Dec 1
82 20041327 PXR-mediated induction of P-glycoprotein by anticancer drugs in a human colon adenocarcinoma-derived cell line. 2010 Sep 2
83 20628376 Effect of ABCB1 C3435T polymorphism on docetaxel pharmacokinetics according to menopausal status in breast cancer patients. 2010 Aug 10 3
84 20829196 I-387, a novel antimitotic indole, displays a potent in vitro and in vivo antitumor activity with less neurotoxicity. 2010 Nov 2
85 18812689 MDR1 single nucleotide polymorphism G2677T/A and haplotype are correlated with response to docetaxel-cisplatin chemotherapy in patients with non-small-cell lung cancer. 2009 3
86 19262372 Inhibition of P-glycoprotein-mediated docetaxel efflux sensitizes ovarian cancer cells to concomitant docetaxel and SN-38 exposure. 2009 Apr 4
87 19332043 Side effects after docetaxel treatment in Taiwanese breast cancer patients with CYP3A4, CYP3A5, and ABCB1 gene polymorphisms. 2009 Jun 27 1
88 17876342 PXR, CAR and HNF4alpha genotypes and their association with pharmacokinetics and pharmacodynamics of docetaxel and doxorubicin in Asian patients. 2008 Apr 1
89 18063021 Expression and activity of taxane-metabolizing enzymes in ovarian tumors. 2008 Feb 1
90 18281755 [Prediction of response to docetaxel in breast cancer]. 2008 Feb 1
91 18628469 ABCB1 genetic variation influences the toxicity and clinical outcome of patients with androgen-independent prostate cancer treated with docetaxel. 2008 Jul 15 6
92 19001875 Hypermethylation of the ABCB1 downstream gene promoter accompanies ABCB1 gene amplification and increased expression in docetaxel-resistant MCF-7 breast tumor cells. 2008 Sep 4
93 17256132 Influence of ketoconazole on the fecal and urinary disposition of docetaxel. 2007 Sep 2
94 17683514 Pilot study of MDR1 gene transfer into hematopoietic stem cells and chemoprotection in metastatic breast cancer patients. 2007 Oct 2
95 17907967 Retroviral integration site analysis and the fate of transduced clones in an MDR1 gene therapy protocol targeting metastatic breast cancer. 2007 Oct 2
96 17912240 ZD6474 reverses multidrug resistance by directly inhibiting the function of P-glycoprotein. 2007 Oct 8 2
97 16518057 Gene therapy for breast cancer. --Review of clinical gene therapy trials for breast cancer and MDR1 gene therapy trial in Cancer Institute Hospital. 2006 1
98 16529050 [Gene therapy for relapsed breast cancer]. 2006 Mar 1
99 16805818 Predictive factors for response to docetaxel in human breast cancers. 2006 Sep 1
100 17020985 Pharmacogenetic screening of CYP3A and ABCB1 in relation to population pharmacokinetics of docetaxel. 2006 Oct 1 5