| 1 |
33762959 | Meta-Analysis of ABCG2 and ABCB1 Polymorphisms With Sunitinib-Induced Toxicity and Efficacy in Renal Cell Carcinoma. | 2021 |
5 |
| 2 |
31023123 | Influence of ABCB1 (1236C > T, 2677G > T and 3435C > T) polymorphisms on the transport ability of P-gp-mediated sunitinib in Caco-2 cell line. | 2020 Mar |
13 |
| 3 |
32041631 | Y-box binding protein-1 is crucial in acquired drug resistance development in metastatic clear-cell renal cell carcinoma. | 2020 Feb 10 |
2 |
| 4 |
32921632 | LINC00160 mediates sunitinib resistance in renal cell carcinoma via SAA1 that is implicated in STAT3 activation and compound transportation. | 2020 Sep 13 |
1 |
| 5 |
29581831 | Association analysis of SNPs present in plasma with adverse events and population pharmacokinetics in Chinese sunitinib treated patients with renal cell carcinoma. | 2018 Mar 6 |
1 |
| 6 |
30070687 | Characterization of the breast cancer resistance protein (BCRP/ABCG2) in clear cell renal cell carcinoma. | 2018 Dec 15 |
2 |
| 7 |
27564227 | Clinical effects of single nucleotide polymorphisms on drug-related genes in Japanese metastatic renal cell carcinoma patients treated with sunitinib. | 2017 Jan |
1 |
| 8 |
28143610 | Severe toxicity induced by accumulation of active sunitinib metabolite in a Japanese patient with renal cell carcinoma: a case report. | 2017 Feb 1 |
1 |
| 9 |
28381801 | Association of Single Nucleotide Polymorphisms in STAT3, ABCB1, and ABCG2 with Stomatitis in Patients with Metastatic Renal Cell Carcinoma Treated with Sunitinib: A Retrospective Analysis in Japanese Patients. | 2017 |
3 |
| 10 |
25778465 | Effect of the CYP3A5 and ABCB1 genotype on exposure, clinical response and manifestation of toxicities from sunitinib in Asian patients. | 2016 Feb |
4 |
| 11 |
27485537 | BSA and ABCB1 polymorphism affect the pharmacokinetics of sunitinib and its active metabolite in Asian mRCC patients receiving an attenuated sunitinib dosing regimen. | 2016 Sep |
6 |
| 12 |
25455500 | Elacridar enhances the cytotoxic effects of sunitinib and prevents multidrug resistance in renal carcinoma cells. | 2015 Jan 5 |
2 |
| 13 |
25930089 | CYP3A5 and ABCB1 polymorphisms as predictors for sunitinib outcome in metastatic renal cell carcinoma. | 2015 Oct |
3 |
| 14 |
26244574 | Association of ABCB1 and FLT3 Polymorphisms with Toxicities and Survival in Asian Patients Receiving Sunitinib for Renal Cell Carcinoma. | 2015 |
2 |
| 15 |
26312386 | Resistance to sunitinib in renal clear cell carcinoma results from sequestration in lysosomes and inhibition of the autophagic flux. | 2015 |
2 |
| 16 |
24234588 | Predictive value of CYP3A and ABCB1 phenotyping probes for the pharmacokinetics of sunitinib: the ClearSun study. | 2014 Mar |
1 |
| 17 |
24566734 | Association analysis of genetic polymorphisms in genes related to sunitinib pharmacokinetics, specifically clearance of sunitinib and SU12662. | 2014 Jul |
1 |
| 18 |
24874929 | Efflux pump ABCB1 single nucleotide polymorphisms and dose reductions in patients with metastatic renal cell carcinoma treated with sunitinib. | 2014 Oct |
2 |
| 19 |
23448320 | Colchicine toxicity precipitated by interaction with sunitinib. | 2013 Jun |
1 |
| 20 |
23462807 | Single-nucleotide polymorphisms associated with outcome in metastatic renal cell carcinoma treated with sunitinib. | 2013 Mar 5 |
1 |
| 21 |
21351087 | Brain accumulation of sunitinib is restricted by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and can be enhanced by oral elacridar and sunitinib coadministration. | 2012 Jan 1 |
1 |
| 22 |
22673043 | Impact of genetic variation in breast cancer resistance protein (BCRP/ABCG2) on sunitinib pharmacokinetics. | 2012 |
3 |
| 23 |
20345483 | Pharmacological interaction with sunitinib is abolished by a germ-line mutation (1291T>C) of BCRP/ABCG2 gene. | 2010 Jun |
2 |
| 24 |
20446917 | siRNA-mediated knock-down of P-glycoprotein expression reveals distinct cellular disposition of anticancer tyrosine kinases inhibitors. | 2010 Apr |
1 |
| 25 |
18971320 | Sunitinib (Sutent, SU11248), a small-molecule receptor tyrosine kinase inhibitor, blocks function of the ATP-binding cassette (ABC) transporters P-glycoprotein (ABCB1) and ABCG2. | 2009 Feb |
12 |
| 26 |
19232821 | Sensitization of ABCG2-overexpressing cells to conventional chemotherapeutic agent by sunitinib was associated with inhibiting the function of ABCG2. | 2009 Jun 28 |
5 |
| 27 |
19773380 | Interaction of the multikinase inhibitors sorafenib and sunitinib with solute carriers and ATP-binding cassette transporters. | 2009 Oct 1 |
1 |