Cholesterol

ATP binding cassette subfamily B member 1 ; Homo sapiens







91 Article(s)
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1 34915026 Dependence of ABCB1 transporter expression and function on distinct sphingolipids generated by ceramide synthases-2 and -6 in chemoresistant renal cancer. 2022 Feb 1
2 33350827 Cholesterol Asymmetrically Modulates the Conformational Ensemble of the Nucleotide-Binding Domains of P-Glycoprotein in Lipid Nanodiscs. 2021 Jan 12 3
3 33672718 Molecular Regulation of Canalicular ABC Transporters. 2021 Feb 20 1
4 34506133 Effect of the Force Field on Molecular Dynamics Simulations of the Multidrug Efflux Protein P-Glycoprotein. 2021 Oct 12 1
5 31676371 Probing cholesterol binding and translocation in P-glycoprotein. 2020 Jan 1 11
6 32325757 Trimeric Small Interfering RNAs and Their Cholesterol-Containing Conjugates Exhibit Improved Accumulation in Tumors, but Dramatically Reduced Silencing Activity. 2020 Apr 18 1
7 32343987 Hsp90 facilitates acquired drug resistance of tumor cells through cholesterol modulation however independent of tumor progression. 2020 Aug 1
8 31718159 Aptamer-Based Erythrocyte-Derived Mimic Vesicles Loaded with siRNA and Doxorubicin for the Targeted Treatment of Multidrug-Resistant Tumors. 2019 Dec 11 2
9 28189737 The ABCB1 2677G>T/A polymorphism is associated with baseline blood HDL-cholesterol levels in newly diagnosed hyperlipidemic patients. 2018 Mar - Apr 1
10 29353693 Multiscale molecular dynamics simulations of lipid interactions with P-glycoprotein in a complex membrane. 2018 Mar 1
11 30526541 Activation of LXRɑ/β by cholesterol in malignant ascites promotes chemoresistance in ovarian cancer. 2018 Dec 10 3
12 27796655 Retrograde cholesterol transport in the human Caco-2/TC7 cell line: a model to study trans-intestinal cholesterol excretion in atherogenic and diabetic dyslipidemia. 2017 Feb 1
13 28325287 Cholesterol-Containing Nuclease-Resistant siRNA Accumulates in Tumors in a Carrier-free Mode and Silences MDR1 Gene. 2017 Mar 17 1
14 28710789 ATR-101 inhibits cholesterol efflux and cortisol secretion by ATP-binding cassette transporters, causing cytotoxic cholesterol accumulation in adrenocortical carcinoma cells. 2017 Oct 1
15 28903085 Multiscale molecular dynamics simulations of lipid interactions with P-glycoprotein in a complex membrane. 2017 Oct 1
16 26704667 Cholesterol-dependent conformational changes of P-glycoprotein are detected by the 15D3 monoclonal antibody. 2016 Mar 4
17 26724201 Understanding the accumulation of P-glycoprotein substrates within cells: The effect of cholesterol on membrane partitioning. 2016 Apr 6
18 27152239 Multidrug resistance P-glycoprotein dampens SR-BI cholesteryl ester uptake from high density lipoproteins in human leukemia cells. 2016 1
19 27251372 Effect of vildagliptin and pravastatin combination on cholesterol efflux in adipocytes. 2016 Jul 1
20 25603048 ABCB1, ABCC1, and LRP gene expressions are altered by LDL, HDL, and serum deprivation in a human doxorubicin-resistant uterine sarcoma cell line. 2015 Feb 20 1
21 25640268 Lipid regulation of the ABCB1 and ABCG2 multidrug transporters. 2015 2
22 26026069 α-Tocopherols modify the membrane dipole potential leading to modulation of ligand binding by P-glycoprotein. 2015 Aug 2
23 26046259 Calcium and P-glycoprotein independent synergism between schweinfurthins and verapamil. 2015 4
24 24505408 Drug-induced trafficking of p-glycoprotein in human brain capillary endothelial cells as demonstrated by exposure to mitomycin C. 2014 1
25 24648507 Low-density lipoprotein and ritonavir: an interaction between antiretrovirals and lipids mediated by P-glycoprotein. 2014 Jul 1
26 25172973 Possible association of ABCB1:c.3435T>C polymorphism with high-density-lipoprotein-cholesterol response to statin treatment--a pilot study. 2014 Aug 14 2
27 25273894 The effect of two novel cholesterol-lowering agents, disodium ascorbyl phytostanol phosphate (DAPP) and nanostructured aluminosilicate (NSAS) on the expression and activity of P-glycoprotein within Caco-2 cells. 2014 Oct 1 1
28 23473805 Lipid raft modulation by Rp1 reverses multidrug resistance via inactivating MDR-1 and Src inhibition. 2013 May 15 2
29 24225025 Omega 3 fatty acids chemosensitize multidrug resistant colon cancer cells by down-regulating cholesterol synthesis and altering detergent resistant membranes composition. 2013 Nov 13 4
30 22223861 Loss of liver FA binding protein significantly alters hepatocyte plasma membrane microdomains. 2012 Mar 4
31 22858002 Intracellular trafficking mechanism, from intracellular uptake to extracellular efflux, for phospholipid/cholesterol liposomes. 2012 Nov 1
32 20946921 A LDL-masked liposomal-doxorubicin reverses drug resistance in human cancer cells. 2011 Jan 20 1
33 21392722 The C3435T polymorphism in ABCB1 influences atorvastatin efficacy and muscle symptoms in a high-risk vascular cohort. 2011 Mar-Apr 1
34 21445698 Effect of ABCB1 genotype on pre- and post-cardiac transplantation plasma lipid concentrations. 2011 Jun 1
35 21786699 [Effect of cholesterol on the functional activity of proteins responsible for the resistance of human lymphocytes to xenobiotics]. 2011 May-Jun 8
36 19802823 Influence of genetic variation in CYP3A4 and ABCB1 on dose decrease or switching during simvastatin and atorvastatin therapy. 2010 Jan 1
37 20220747 Pharmacokinetic and pharmacodynamic interactions between the immunosuppressant sirolimus and the lipid-lowering drug ezetimibe in healthy volunteers. 2010 Jun 1
38 20586189 [Cholesterol-modified anti-MDR1 small interfering RNA: uptake and biological activity]. 2010 Mar-Apr 1
39 20712525 Pharmacogenetic interactions between ABCB1 and SLCO1B1 tagging SNPs and the effectiveness of statins in the prevention of myocardial infarction. 2010 Aug 1
40 20944122 Caveolin-1 and doxorubicin-induced P-glycoprotein modulate plasma cholesterol membrane accessibility in erythrolymphoblastic cell line. 2010 Sep 6
41 18837012 Comparison of blood-brain barrier permeability assays: in situ brain perfusion, MDR1-MDCKII and PAMPA-BBB. 2009 Jun 1
42 18851956 ABCB1 and ABCC1 expression in peripheral mononuclear cells is influenced by gene polymorphisms and atorvastatin treatment. 2009 Jan 1 3
43 18937360 Cholesterol-mediated activation of P-glycoprotein: distinct effects on basal and drug-induced ATPase activities. 2009 May 5
44 19285054 Association of ABCB1 gene polymorphisms with plasma lipid and apolipoprotein concentrations in the STANISLAS cohort. 2009 May 1
45 19394420 Decreased ABCB1 mRNA expression induced by atorvastatin results from enhanced mRNA degradation in HepG2 cells. 2009 Jun 28 1
46 19530968 Impact of cholesterol on ABC and SLC transporters expression and function and its role in disposition variability to lipid-lowering drugs. 2009 Jun 2
47 19538007 Liposome composition is important for retention of liposomal rhodamine in P-glycoprotein-overexpressing cancer cells. 2009 Jul 1
48 19651114 Lipid dependence of ABC transporter localization and function. 2009 Oct 2
49 19891551 Common genetic variation in the ABCB1 gene is associated with the cholesterol-lowering effect of simvastatin in males. 2009 Nov 7
50 18288958 Genuine functions of P-glycoprotein (ABCB1). 2008 Feb 1