Paclitaxel

ATP binding cassette subfamily B member 1 ; Homo sapiens







527 Article(s)
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1 34896572 Repositioning application of polyoxyethylene (20) sorbitan monooleate on ocular drug resistance and cancer multi-drug resistance by inhibiting the ATPase activity of human multidrug resistance protein 1 and P-glycoprotein. 2022 Jan 2
2 34927791 Unexpected gene activation following CRISPR-Cas9-mediated genome editing. 2022 Feb 3 1
3 35173861 Apatinib inhibits paclitaxel resistance of gastric carcinoma cells through VEGFR2 pathway. 2022 1
4 35186774 Corrigendum: Generation of Two Paclitaxel-Resistant High-Grade Serous Carcinoma Cell Lines With Increased Expression of P-Glycoprotein. 2022 1
5 35205672 DKK3, Downregulated in Invasive Epithelial Ovarian Cancer, Is Associated with Chemoresistance and Enhanced Paclitaxel Susceptibility via Inhibition of the β-Catenin-P-Glycoprotein Signaling Pathway. 2022 Feb 12 2
6 35240035 Utilization of Photoaffinity Labeling to Investigate Binding of Microtubule Stabilizing Agents to P-Glycoprotein and β-Tubulin. 2022 Mar 25 2
7 35327403 Infigratinib (BGJ 398), a Pan-FGFR Inhibitor, Targets P-Glycoprotein and Increases Chemotherapeutic-Induced Mortality of Multidrug-Resistant Tumor Cells. 2022 Mar 3 3
8 35330134 Interaction Analysis of MRP1 with Anticancer Drugs Used in Ovarian Cancer: In Silico Approach. 2022 Mar 7 2
9 35350768 The Resistance of Cancer Cells to Palbociclib, a Cyclin-Dependent Kinase 4/6 Inhibitor, is Mediated by the ABCB1 Transporter. 2022 3
10 35449387 Ketone-selenoesters as potential anticancer and multidrug resistance modulation agents in 2D and 3D ovarian and breast cancer in vitro models. 2022 Apr 21 1
11 35533911 An ester derivative of tenacigenin B from Marsdenia tenacissima (Roxb.) Wight et Arn reversed paclitaxel-induced MDR in vitro and in vivo by inhibiting both P-gp and MRP2. 2022 Aug 10 3
12 35614289 Bioactivity inspired C19-diterpenoid alkaloids for overcoming multidrug-resistant cancer. 2022 May 25 1
13 33289076 PAMAM G4.5 dendrimers for targeted delivery of ferulic acid and paclitaxel to overcome P-glycoprotein-mediated multidrug resistance. 2021 Mar 7
14 33326171 GSTP1 and ABCB1 Polymorphisms Predicting Toxicities and Clinical Management on Carboplatin and Paclitaxel-Based Chemotherapy in Ovarian Cancer. 2021 Mar 1
15 33360797 Design, synthesis, and biological evaluation of hederagenin derivatives with improved aqueous solubility and tumor resistance reversal activity. 2021 Feb 5 2
16 33429062 Formulation effects on paclitaxel transfer and uptake in the human placenta. 2021 Apr 1
17 33506275 Differential expression of ABCB1, ABCG2, and KLF4 as putative indicators for paclitaxel resistance in human epithelial type 2 cells. 2021 Feb 3
18 33506900 Exosomes derived from Taxol-resistant nasopharyngeal carcinoma (NPC) cells transferred DDX53 to NPC cells and promoted cancer resistance to Taxol. 2021 Jan 2
19 33545700 Recent progress in nanoformulations of cabazitaxel. 2021 Feb 5 1
20 33729781 Discovery of Encequidar, First-in-Class Intestine Specific P-glycoprotein Inhibitor. 2021 Apr 8 1
21 33793827 Physcion-8-O-β-d-glucoside interferes with the nuclear factor-κB pathway and downregulates P-glycoprotein expression to reduce paclitaxel resistance in ovarian cancer cells. 2021 Mar 8 1
22 33795638 Utidelone inhibits growth of colorectal cancer cells through ROS/JNK signaling pathway. 2021 Apr 1 1
23 33875073 Polyethyleneimine- -Tocopherol Hydrogen Succinate/Hyaluronic Acid-Quercetin (PEI-TOS/HA-QU) Core-Shell Micelles Delivering Paclitaxel for Combinatorial Treatment of MDR Breast Cancer. 2021 Mar 1 1
24 33960504 Oral paclitaxel with encequidar compared to intravenous paclitaxel in patients with advanced cancer: A randomised crossover pharmacokinetic study. 2021 Dec 2
25 34011375 Graphene oxide (GO)-based nanosheets with combined chemo/photothermal/photodynamic therapy to overcome gastric cancer (GC) paclitaxel resistance by reducing mitochondria-derived adenosine-triphosphate (ATP). 2021 May 19 4
26 34022909 pH-activated, mitochondria-targeted, and redox-responsive delivery of paclitaxel nanomicelles to overcome drug resistance and suppress metastasis in lung cancer. 2021 May 22 1
27 34031188 TP53 Null Mutations Identify Lung Cancer Cell Lines with Highest Sensitivity to the Nontaxane Microtubule Inhibitor Eribulin. 2021 Aug 1
28 34268580 Differences in P-glycoprotein activity in human and rodent blood-brain barrier assessed by mechanistic modelling. 2021 Sep 2
29 34270886 Histone demethylase KDM5A enhances cell proliferation, induces EMT in lung adenocarcinoma cells, and have a strong causal association with paclitaxel resistance. 2021 Jul 16 2
30 34276826 Exploring the potential of functional polymer-lipid hybrid nanoparticles for enhanced oral delivery of paclitaxel. 2021 May 2
31 34280009 ABCB1 Single Nucleotide Polymorphism Genotypes as Predictors of Paclitaxel-Induced Peripheral Neuropathy in Breast Cancer. 2021 Jul 4
32 34313784 Drug resistance via radixin-mediated increase of P-glycoprotein membrane expression during SNAI1-induced epithelial-mesenchymal transition in HepG2 cells. 2021 Dec 7 2
33 34347777 Lapatinib and poziotinib overcome ABCB1-mediated paclitaxel resistance in ovarian cancer. 2021 7
34 34360846 Effects of Dihydrotanshinone I on Proliferation and Invasiveness of Paclitaxel-Resistant Anaplastic Thyroid Cancer Cells. 2021 Jul 28 1
35 34617400 Targeted paclitaxel-octreotide conjugates inhibited the growth of paclitaxel-resistant human non-small cell lung cancer A549 cells in vitro. 2021 Nov 1
36 34648615 Host cells with transient overexpression of MDR1 as a novel in vitro model for evaluating on-target effect for activity against the epicellular Cryptosporidium parasite. 2021 Dec 24 1
37 34723530 Discovery of the Triazolo[1,5-a]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance. 2021 Nov 11 4
38 34745981 Generation of Two Paclitaxel-Resistant High-Grade Serous Carcinoma Cell Lines With Increased Expression of P-Glycoprotein. 2021 1
39 34835622 A Multifunctional Polymeric Micelle for Targeted Delivery of Paclitaxel by the Inhibition of the P-Glycoprotein Transporters. 2021 Oct 26 3
40 34858183 Tissue Type Differences in ABCB1 Expression and Paclitaxel Tissue Pharmacokinetics in Patients With Esophageal Cancer. 2021 1
41 34977876 Overcoming multidrug resistance by knockout of ABCB1 gene using CRISPR/Cas9 system in SW620/Ad300 colorectal cancer cells. 2021 Dec 2
42 31628941 Inhibition of aldehyde dehydrogenase-1 and p-glycoprotein-mediated multidrug resistance by curcumin and vitamin D3 increases sensitivity to paclitaxel in breast cancer. 2020 Jan 5 3
43 31846802 Gene/paclitaxel co-delivering nanocarriers prepared by framework-induced self-assembly for the inhibition of highly drug-resistant tumors. 2020 Feb 4
44 31937590 Peripheral neuropathy from paclitaxel: risk prediction by serum microRNAs. 2020 Jan 14 1
45 31967866 Reversal of P-glycoprotein-mediated multidrug resistance by novel curcumin analogues in paclitaxel-resistant human breast cancer cells. 2020 Aug 1
46 31993509 Microtubule-targeting anticancer drug eribulin induces drug efflux transporter P-glycoprotein. 2020 Mar 5
47 32092870 Overexpression of ABCB1 Transporter Confers Resistance to mTOR Inhibitor WYE-354 in Cancer Cells. 2020 Feb 19 1
48 32108588 Identification of a lathyrane-type diterpenoid EM-E-11-4 as a novel paclitaxel resistance reversing agent with multiple mechanisms of action. 2020 Feb 28 3
49 32156786 Decitabine Response in Breast Cancer Requires Efficient Drug Processing and Is Not Limited by Multidrug Resistance. 2020 May 1
50 32176509 Folic Acid-Modified Nanoerythrocyte for Codelivery of Paclitaxel and Tariquidar to Overcome Breast Cancer Multidrug Resistance. 2020 Apr 6 1