Vinblastine

ATP binding cassette subfamily B member 1 ; Homo sapiens







245 Article(s)
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151 9744556 Kinetic analysis in living cells of the inhibition of the P-glycoprotein-mediated efflux of anthracyclines by vinca alkaloids. 1998 Jul 3 3
152 9756763 Secretion of sparfloxacin from the human intestinal Caco-2 cell line is altered by P-glycoprotein inhibitors. 1998 Oct 1
153 9792953 Swelling-activated chloride currents in a drug-sensitive cell line and a P glycoprotein-expressing derivative are underlied by channels with the same pharmacological properties. 1998 2
154 9803961 Interaction of anti-HIV protease inhibitors with the multidrug transporter P-glycoprotein (P-gp) in human cultured cells. 1998 Nov 1 1
155 9914792 Inhibitory effects of a cyclosporin derivative, SDZ PSC 833, on transport of doxorubicin and vinblastine via human P-glycoprotein. 1998 Nov 3
156 9038218 Multidrug-resistant human sarcoma cells with a mutant P-glycoprotein, altered phenotype, and resistance to cyclosporins. 1997 Feb 28 2
157 9119038 Competitive and non-competitive inhibition of the multidrug-resistance-associated P-glycoprotein ATPase--further experimental evidence for a multisite model. 1997 Mar 1 6
158 9220975 Alteration of substrate specificity by mutations at the His61 position in predicted transmembrane domain 1 of human MDR1/P-glycoprotein. 1997 Jul 22 1
159 9257720 MDR-1 gene expression is a minor factor in determining the multidrug resistance phenotype of MCF7/ADR and KB-V1 cells. 1997 Jul 21 1
160 9261121 Relation between the turnover number for vinblastine transport and for vinblastine-stimulated ATP hydrolysis by human P-glycoprotein. 1997 Aug 22 7
161 9283689 Fluoroquinolone (ciprofloxacin) secretion by human intestinal epithelial (Caco-2) cells. 1997 Aug 2
162 9287320 Phosphorylation site mutations in the human multidrug transporter modulate its drug-stimulated ATPase activity. 1997 Sep 12 2
163 9332327 Mitochondrial electron transport chain activity, but not ATP synthesis, is required for drug-induced apoptosis in human leukaemic cells: a possible novel mechanism of regulating drug resistance. 1997 Sep 5
164 9380680 Evidence for two nonidentical drug-interaction sites in the human P-glycoprotein. 1997 Sep 30 2
165 9380755 p53-dependent regulation of MDR1 gene expression causes selective resistance to chemotherapeutic agents. 1997 Sep 30 1
166 9405384 Identification of residues in the drug-binding site of human P-glycoprotein using a thiol-reactive substrate. 1997 Dec 19 1
167 9413166 Drug resistance conferred by MDR1 expression in spheroids formed by glioblastoma cell lines. 1997 Sep-Oct 4
168 8564974 Reversal of multidrug resistance in vivo by dietary administration of the phytochemical indole-3-carbinol. 1996 Feb 1 2
169 8603454 Trifluoperazine as a modulator of multidrug resistance in refractory breast cancer. 1996 1
170 8605104 Alterations in expression of the multidrug resistance-associated protein (MRP) gene in high-grade transitional cell carcinoma of the bladder. 1996 Mar 1
171 8612315 Reversal of doxorubicin, etoposide, vinblastine, and taxol resistance in multidrug resistant human sarcoma cells by a polymer of spermine. 1996 1
172 8640766 Resistance mechanisms in human sarcoma mutants derived by single-step exposure to paclitaxel (Taxol). 1996 Mar 1 1
173 8664272 Steroid treatment, accumulation, and antagonism of P-glycoprotein in multidrug-resistant cells. 1996 Apr 16 1
174 8794885 BIBW22 BS, potent multidrug resistance-reversing agent, binds directly to P-glycoprotein and accumulates in drug-resistant cells. 1996 Sep 1
175 8826855 Effects of the selective bisindolylmaleimide protein kinase C inhibitor GF 109203X on P-glycoprotein-mediated multidrug resistance. 1996 Sep 1
176 8940082 Role of the stress-activated/c-Jun NH2-terminal protein kinase pathway in the cellular response to adriamycin and other chemotherapeutic drugs. 1996 Nov 29 1
177 8953513 Active secretion of drugs from the small intestinal epithelium in rats by P-glycoprotein functioning as an absorption barrier. 1996 Oct 1
178 8980113 Aureobasidin A, an antifungal cyclic depsipeptide antibiotic, is a substrate for both human MDR1 and MDR2/P-glycoproteins. 1996 Dec 9 3
179 7476894 A structure-function relationship among reserpine and yohimbine analogues in their ability to increase expression of mdr1 and P-glycoprotein in a human colon carcinoma cell line. 1995 Oct 2
180 7543490 Downregulation of mdr-1 expression by 8-Cl-cAMP in multidrug resistant MCF-7 human breast cancer cells. 1995 Aug 1
181 7559420 Characterization of prenylcysteines that interact with P-glycoprotein and inhibit drug transport in tumor cells. 1995 Sep 29 1
182 7598747 Allosteric regulation of [3H]vinblastine binding to P-glycoprotein of MCF-7 ADR cells by dexniguldipine. 1995 Jun 16 3
183 7629047 Purification and reconstitution of functional human P-glycoprotein. 1995 Feb 1
184 7632162 Novel dithiane analogues of tiapamil with high activity to overcome multidrug resistance in vitro. 1995 Jul 17 1
185 7643631 Detection of P-glycoprotein with a rapid flow cytometric functional assay using Fluo-3: evaluation of sensitivity, specificity and feasibility in multiparametric analysis. 1995 Aug 3
186 7670142 Development of drug resistance is reduced with idarubicin relative to other anthracyclines. 1995 Jun 1
187 7738186 Generation of a drug resistance profile by quantitation of mdr-1/P-glycoprotein in the cell lines of the National Cancer Institute Anticancer Drug Screen. 1995 May 1
188 7822320 Membrane topology of a cysteine-less mutant of human P-glycoprotein. 1995 Jan 13 1
189 7841043 Interaction of tamoxifen with the multidrug resistance P-glycoprotein. 1995 Feb 3
190 7896810 Mutation of glycine 185 to valine alters the ATPase function of the human P-glycoprotein expressed in Sf9 cells. 1995 Mar 24 3
191 8835287 Differential interactions of cytochalasins with P-glycoprotein. 1995 1
192 9384669 Modulation of vindesine and doxorubicin resistance in multidrug-resistant pleural mesothelioma cells by tumor necrosis factor-alpha. 1995 Jun 2
193 7705462 Dexniguldipine-HCl is a potent allosteric inhibitor of [3H]vinblastine binding to P-glycoprotein of CCRF ADR 5000 cells. 1994 Dec 15 1
194 7848886 P-glycoprotein expression in primary and metastatic transitional cell carcinoma of the bladder. 1994 Nov 1
195 7865904 P-glycoprotein mediates profound resistance to bisantrene. 1994 2
196 7872686 Effects of vinblastine, colchicine, and verapamil on rhodamine 123 accumulation in human P-glycoprotein-positive leukemia cells. 1994 Nov-Dec 3
197 7904476 N-(p-azido-3-[125I]iodophenethyl)spiperone binds to specific regions of P-glycoprotein and another multidrug binding protein, spiperophilin, in human neuroblastoma cells. 1994 Jan 11 1
198 7909435 Drugs transported by P-glycoprotein inhibit a 40 pS outwardly rectifying chloride channel. 1994 Apr 15 1
199 7909520 The multidrug-resistance-reverser verapamil interferes with cellular P-glycoprotein-mediated pumping of daunorubicin as a non-competing substrate. 1994 Apr 1 1
200 7910786 Inhibition of P-glycoprotein-mediated vinblastine transport across HCT-8 intestinal carcinoma monolayers by verapamil, cyclosporine A and SDZ PSC 833 in dependence on extracellular pH. 1994 1