| 101 |
12235267 | Interaction of cytochrome P450 3A inhibitors with P-glycoprotein. | 2002 Oct |
2 |
| 102 |
12415630 | P-glycoprotein expression by cancer cells affects cell cytotoxicity and cell-cycle perturbations induced by six chemotherapeutic drugs. | 2002 May-Jun |
1 |
| 103 |
12425469 | Effect of organic isothiocyanates on the P-glycoprotein- and MRP1-mediated transport of daunomycin and vinblastine. | 2002 Oct |
2 |
| 104 |
12431060 | Effects of isoprenoid analogues of SDB-ethylenediamine on multidrug resistant tumor cells alone and in combination with chemotherapeutic drugs. | 2002 Nov 21 |
1 |
| 105 |
12534340 | Characterization and application of a vinblastine-selected CACO-2 cell line for evaluation of p-glycoprotein. | 2002 Jul-Aug |
1 |
| 106 |
11125025 | Competitive and allosteric interactions in ligand binding to P-glycoprotein as observed on an immobilized P-glycoprotein liquid chromatographic stationary phase. | 2001 Jan |
2 |
| 107 |
11284688 | P-glycoprotein-mediated colchicine resistance in different cell lines correlates with the effects of colchicine on P-glycoprotein conformation. | 2001 Apr 10 |
5 |
| 108 |
11288109 | P-glycoprotein efflux pump expression and activity in Calu-3 cells. | 2001 May |
2 |
| 109 |
11336351 | A human lymphocyte based ex vivo assay to study the effect of drugs on P-glycoprotein (P-gp) function. | 2001 Jan |
2 |
| 110 |
11408558 | P-glycoprotein-mediated efflux of indinavir metabolites in Caco-2 cells expressing cytochrome P450 3A4. | 2001 Jul |
1 |
| 111 |
11465412 | P-glycoprotein inhibition leads to enhanced disruptive effects by anti-microtubule cytostatics at the in vitro blood-brain barrier. | 2001 May |
2 |
| 112 |
11504821 | Multidrug resistance-associated protein-1 functional activity in Calu-3 cells. | 2001 Sep |
1 |
| 113 |
11606389 | The farnesyl protein transferase inhibitor SCH66336 is a potent inhibitor of MDR1 product P-glycoprotein. | 2001 Oct 15 |
3 |
| 114 |
10601617 | Clofazimine and B4121 sensitize an intrinsically resistant human colon cancer cell line to P-glycoprotein substrates. | 2000 Jan-Feb |
2 |
| 115 |
10631102 | Overexpression of MDR1 in an intestinal cell line results in increased cholesterol uptake from micelles. | 2000 Jan 19 |
1 |
| 116 |
10724034 | Chemoprotection of hematopoietic cells by a mutant P-glycoprotein resistant to a potent chemosensitizer of multidrug-resistant cancers. | 2000 Mar 1 |
1 |
| 117 |
10727237 | Activation of the human P-glycoprotein ATPase by trypsin. | 2000 Mar 28 |
2 |
| 118 |
10734174 | Polymethoxylated flavones in orange juice are inhibitors of P-glycoprotein but not cytochrome P450 3A4. | 2000 Apr |
2 |
| 119 |
10739116 | Localization of the 1,4-dihydropyridine drug acceptor of P-glycoprotein to a cytoplasmic domain using a permanently charged derivative N-methyl dexniguldipine. | 2000 Mar |
3 |
| 120 |
10744311 | Development of an immobilized P-glycoprotein stationary phase for on-line liquid chromatographic determination of drug-binding affinities. | 2000 Feb 28 |
6 |
| 121 |
10764626 | Low-level doxorubicin resistance in benzo[a]pyrene-treated KB-3-1 cells is associated with increased LRP expression and altered subcellular drug distribution. | 2000 Apr 15 |
1 |
| 122 |
10772630 | In vitro flow cytometry method to quantitatively assess inhibitors of P-glycoprotein. | 2000 May |
2 |
| 123 |
10837354 | Role of multidrug resistance P-glycoprotein in the secretion of aldosterone by human adrenal NCI-H295 cells. | 2000 Jun |
1 |
| 124 |
10838122 | Functional expression of P-glycoprotein in primary cultures of human cytotrophoblasts and BeWo cells. | 2000 May-Jun |
2 |
| 125 |
10841824 | Blockage of drug resistance in vitro by disulfiram, a drug used to treat alcoholism. | 2000 Jun 7 |
1 |
| 126 |
10871337 | Detoxication of vinca alkaloids by human P450 CYP3A4-mediated metabolism: implications for the development of drug resistance. | 2000 Jul |
2 |
| 127 |
10872505 | Detection of recombinant P-glycoprotein in multidrug resistant cultured cells. | 2000 Feb |
2 |
| 128 |
10918072 | MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping. | 2000 Aug 4 |
2 |
| 129 |
10953057 | Communication between multiple drug binding sites on P-glycoprotein. | 2000 Sep |
1 |
| 130 |
10970691 | MDR 1 activation is the predominant resistance mechanism selected by vinblastine in MES-SA cells. | 2000 Oct |
2 |
| 131 |
11070177 | Human placental transport of vinblastine, vincristine, digoxin and progesterone: contribution of P-glycoprotein. | 2000 Nov 10 |
1 |
| 132 |
11145224 | Astrocytes increase the functional expression of P-glycoprotein in an in vitro model of the blood-brain barrier. | 2000 Oct |
2 |
| 133 |
11303953 | Influence of passive permeability on apparent P-glycoprotein kinetics. | 2000 Dec |
2 |
| 134 |
9862789 | Characterization of binding properties to human P-glycoprotein: development of a [3H]verapamil radioligand-binding assay. | 1999 Jan |
4 |
| 135 |
9864431 | The chemosensitizing potential of GF120918 is independent of the magnitude of P-glycoprotein-mediated resistance to conventional chemotherapeutic agents in a small cell lung cancer line. | 1999 Jan-Feb |
3 |
| 136 |
9891078 | Studies of human MDR1-MDR2 chimeras demonstrate the functional exchangeability of a major transmembrane segment of the multidrug transporter and phosphatidylcholine flippase. | 1999 Feb |
4 |
| 137 |
10075817 | A continuous fluorescence assay for the study of P-glycoprotein-mediated drug efflux using inside-out membrane vesicles. | 1999 Mar 15 |
1 |
| 138 |
10087141 | P-glycoprotein inhibition by glibenclamide and related compounds. | 1999 Apr |
3 |
| 139 |
10100591 | The bisindolylmaleimide protein kinase C inhibitor, Ro 32-2241, reverses multidrug resistance in KB tumour cells. | 1999 |
1 |
| 140 |
10365134 | Altered expression of beta 1 integrins in renal carcinoma cell lines exposed to vinblastine. | 1999 Mar-Apr |
1 |
| 141 |
10411602 | Selectivity of the multidrug resistance modulator, LY335979, for P-glycoprotein and effect on cytochrome P-450 activities. | 1999 Aug |
4 |
| 142 |
10576649 | The acridonecarboxamide GF120918 potently reverses P-glycoprotein-mediated resistance in human sarcoma MES-Dx5 cells. | 1999 Nov |
4 |
| 143 |
10614867 | Evaluation of an in vitro coculture model for the blood-brain barrier: comparison of human umbilical vein endothelial cells (ECV304) and rat glioma cells (C6) from two commercial sources. | 1999 Nov-Dec |
1 |
| 144 |
10665657 | Interaction of docetaxel ("Taxotere") with human P-glycoprotein. | 1999 Dec |
1 |
| 145 |
11498353 | Photoaffinity analogs for multidrug resistance-related transporters and their use in identifying chemosensitizers. | 1999 Dec |
2 |
| 146 |
9607955 | P-Glycoprotein (P-gp) mediated efflux in Caco-2 cell monolayers: the influence of culturing conditions and drug exposure on P-gp expression levels. | 1998 Jun |
1 |
| 147 |
9619779 | P-glycoprotein is more efficient at limiting uptake than inducing efflux of colchicine and vinblastine in HL-60 cells. | 1998 May |
3 |
| 148 |
9657975 | Multidrug resistance transporter P-glycoprotein has distinct but interacting binding sites for cytotoxic drugs and reversing agents. | 1998 Jul 15 |
4 |
| 149 |
9703277 | Reversal of vinblastine transport by chlorpromazine in membrane vesicles from multidrug-resistant human CCRF-CEM leukaemia cells. | 1998 Aug |
5 |
| 150 |
9711577 | Purification and reconstitution of human P-glycoprotein. | 1998 |
1 |