Vinblastine

ATP binding cassette subfamily B member 1 ; Homo sapiens







245 Article(s)
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51 18723777 A novel human multidrug resistance gene MDR1 variant G571A (G191R) modulates cancer drug resistance and efflux transport. 2008 Nov 1
52 18762730 Reversal effects of Ca2+ antagonists on multidrug resistance via down-regulation of MDR1 mRNA. 2008 Feb 8 3
53 17050779 Complete inhibition of P-glycoprotein by simultaneous treatment with a distinct class of modulators and the UIC2 monoclonal antibody. 2007 Jan 1
54 17351391 Correlations between the activities of 19 standard anticancer agents, antioxidative enzyme activities and the expression of ATP-binding cassette transporters: comparison with the National Cancer Institute data. 2007 Apr 1
55 17455112 Role of ATP-binding cassette drug transporters in the intestinal absorption of tanshinone IIB, one of the major active diterpenoids from the root of Salvia miltiorrhiza. 2007 Apr 1
56 17475454 Effect of cell differentiation and passage number on the expression of efflux proteins in wild type and vinblastine-induced Caco-2 cell lines. 2007 Sep 1
57 17541155 Knock-down of sorcin induces up-regulation of MDR1 in HeLa cells. 2007 Jun 1
58 17901905 Reversal of P-glycoprotein-mediated multidrug resistance by cholesterol derived from low density lipoprotein in a vinblastine-resistant human lymphoblastic leukemia cell line. 2007 Oct 1
59 17982279 Cobalamin potentiates vinblastine cytotoxicity through downregulation of mdr-1 gene expression in HepG2 cells. 2007 1
60 18170979 Polyoxyethylene 40 stearate modulates multidrug resistance and enhances antitumor activity of vinblastine sulfate. 2007 Oct 5 2
61 16458258 The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells. 2006 Apr 14 1
62 16458542 Zoledronic acid is synergic with vinblastine to induce apoptosis in a multidrug resistance protein-1 dependent way: an in vitro study. 2006 Mar 2
63 16858128 What kinds of substrates show P-glycoprotein-dependent intestinal absorption? Comparison of verapamil with vinblastine. 2006 Jun 2
64 16917872 A novel MDR1 G1199T variant alters drug resistance and efflux transport activity of P-glycoprotein in recombinant Hek cells. 2006 Dec 1
65 16964701 [Is MDR 1 gene a key to successful chemotherapy?]. 2006 Jun 1
66 17025021 Suppression of multidrug resistance by migrastatin. 2006 Jul 1
67 17064079 Arylmethyloxyphenyl derivatives: small molecules displaying P-glycoprotein inhibition. 2006 Nov 2 2
68 18528466 The individualization of cancer therapy: the unexpected role of p53. 2006 1
69 15667829 Modulation of P-glycoprotein-mediated multidrug resistance in K562 leukemic cells by indole-3-carbinol. 2005 Feb 1 1
70 15728898 Differential bidirectional transfer of indinavir in the isolated perfused human placenta. 2005 Mar 1
71 15766280 Control of P-glycoprotein activity by membrane cholesterol amounts and their relation to multidrug resistance in human CEM leukemia cells. 2005 Mar 22 1
72 15867385 Glucosylceramide synthase blockade down-regulates P-glycoprotein and resensitizes multidrug-resistant breast cancer cells to anticancer drugs. 2005 May 1 2
73 16196493 Rescue of DeltaF508 and other misprocessed CFTR mutants by a novel quinazoline compound. 2005 Sep-Oct 2
74 14754408 Identification and characterization of the binding sites of P-glycoprotein for multidrug resistance-related drugs and modulators. 2004 Jan 1
75 14985103 Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies. 2004 Mar 19 1
76 15042610 YB-1 is upregulated during prostate cancer tumor progression and increases P-glycoprotein activity. 2004 May 15 2
77 15090070 Modulation of human multidrug-resistance MDR-1 gene by natural curcuminoids. 2004 Apr 17 2
78 15100388 Multidrug resistance gene G1199A polymorphism alters efflux transport activity of P-glycoprotein. 2004 Sep 1
79 15139519 Contribution of cholesterol and phospholipids to inhibitory effect of dimethyl-beta-cyclodextrin on efflux function of P-glycoprotein and multidrug resistance-associated protein 2 in vinblastine-resistant Caco-2 cell monolayers. 2004 Apr 2
80 15248030 Inhibition of P-glycoprotein activity and reversal of cancer multidrug resistance by Momordica charantia extract. 2004 Dec 2
81 15269145 A phase I/II study of infusional vinblastine with the P-glycoprotein antagonist valspodar (PSC 833) in renal cell carcinoma. 2004 Jul 15 1
82 15466210 Celastraceae sesquiterpenes as a new class of modulators that bind specifically to human P-glycoprotein and reverse cellular multidrug resistance. 2004 Oct 1 1
83 15467223 Effect of rabeprazole on MDR1-mediated transport of Rhodamine 123 in Caco-2 and Hvr100-6 cells. 2004 Oct 1
84 15472471 Effect of PCB-126 on intracellular accumulation and transepithelial transport of vinblastine in LLC-PK1 and its transformant cells expressing human P-glycoprotein. 2004 Sep 1
85 15476675 Biochemical mechanism of modulation of human P-glycoprotein (ABCB1) by curcumin I, II, and III purified from Turmeric powder. 2004 Nov 15 1
86 15497697 Interactions of human P-glycoprotein with simvastatin, simvastatin acid, and atorvastatin. 2004 Sep 1
87 15621665 P-glycoprotein potentiates CYP3A4-mediated drug disappearance during Caco-2 intestinal secretory detoxification. 2004 1
88 12490309 Modulation of vinca-alkaloid induced P-glycoprotein expression by indole-3-carbinol. 2003 Jan 28 2
89 12490621 Constitutive expression of p-glycoprotein in normal lung alveolar epithelium and functionality in primary alveolar epithelial cultures. 2003 Jan 1
90 12608534 Kinetic analysis of P-glycoprotein-mediated transport by using normal human placental brush-border membrane vesicles. 2003 Jan 1
91 12687290 Ketotifen reverses MDR1-mediated multidrug resistance in human breast cancer cells in vitro and alleviates cardiotoxicity induced by doxorubicin in vivo. 2003 May 1
92 12737312 RU49953: a non-hormonal steroid derivative that potently inhibits P-glycoprotein and reverts cellular multidrug resistance. 2003 Mar 2
93 12948013 Quantitative evaluation of the function of small intestinal P-glycoprotein: comparative studies between in situ and in vitro. 2003 Aug 1
94 11801563 Differences in therapeutic indexes of combination metronomic chemotherapy and an anti-VEGFR-2 antibody in multidrug-resistant human breast cancer xenografts. 2002 Jan 3
95 11911848 Involvement of phosphatidylinositol-3-kinase in membrane ruffling induced by P-glycoprotein substrates in multidrug-resistant carcinoma cells. 2002 Mar 1 1
96 11961113 Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein. 2002 May 2
97 11961114 Application of three-dimensional quantitative structure-activity relationships of P-glycoprotein inhibitors and substrates. 2002 May 1
98 12033380 Can the enhanced renal clearance of antibiotics in cystic fibrosis patients be explained by P-glycoprotein transport? 2002 Apr 2
99 12064912 Activity of drugs from traditional Chinese medicine toward sensitive and MDR1- or MRP1-overexpressing multidrug-resistant human CCRF-CEM leukemia cells. 2002 Mar-Apr 1
100 12081145 Cytotoxic effects of 27 anticancer drugs in HeLa and MDR1-overexpressing derivative cell lines. 2002 Jun 1