| 1 |
35533911 | An ester derivative of tenacigenin B from Marsdenia tenacissima (Roxb.) Wight et Arn reversed paclitaxel-induced MDR in vitro and in vivo by inhibiting both P-gp and MRP2. | 2022 Aug 10 |
1 |
| 2 |
33614822 | Vinblastine treatment decreases the undifferentiated cell contamination of human iPSC-derived intestinal epithelial-like cells. | 2021 Mar 12 |
4 |
| 3 |
32796768 | Transport Oligonucleotides-A Novel System for Intracellular Delivery of Antisense Therapeutics. | 2020 Aug 11 |
2 |
| 4 |
30478158 | Overcoming P-Glycoprotein-Mediated Drug Resistance with Noscapine Derivatives. | 2019 Feb |
1 |
| 5 |
29132176 | Verapamil (VER) Enhances the Cytotoxic Effects of Docetaxel and Vinblastine Combined Therapy Against Non-Small Cell Lung Cancer Cell Lines. | 2018 Mar |
1 |
| 6 |
30149128 | Targeted efflux transporter inhibitors - A solution to improve poor cellular accumulation of anti-cancer agents. | 2018 Oct 25 |
2 |
| 7 |
27114800 | Co-treatment by docetaxel and vinblastine breaks down P-glycoprotein mediated chemo-resistance. | 2016 Mar |
2 |
| 8 |
27405085 | Impact of ABCB1 1236C > T-2677G > T-3435C > T polymorphisms on the anti-proliferative activity of imatinib, nilotinib, dasatinib and ponatinib. | 2016 Jul 12 |
1 |
| 9 |
25695368 | Restoration of Chemosensitivity in P-Glycoprotein-Dependent Multidrug-Resistant Cells by Dihydro-β-agarofuran Sesquiterpenes from Celastrus vulcanicola. | 2015 Apr 24 |
1 |
| 10 |
25776492 | Effects of natural nuclear factor-kappa B inhibitors on anticancer drug efflux transporter human P-glycoprotein. | 2015 Mar |
1 |
| 11 |
26407111 | Human ABCB1 confers cells resistance to cytotoxic guanidine alkaloids from Pterogyne nitens. | 2015 |
4 |
| 12 |
24088727 | Involvement of AP-1 and NF-κB in the up-regulation of P-gp in vinblastine resistant Caco-2 cells. | 2014 |
6 |
| 13 |
24284783 | β-Elemene, a compound derived from Rhizoma zedoariae, reverses multidrug resistance mediated by the ABCB1 transporter. | 2014 Feb |
1 |
| 14 |
24295377 | Tivozanib reverses multidrug resistance mediated by ABCB1 (P-glycoprotein) and ABCG2 (BCRP). | 2014 Aug |
1 |
| 15 |
24621983 | ABCB1 1199G>A genetic polymorphism (Rs2229109) influences the intracellular accumulation of tacrolimus in HEK293 and K562 recombinant cell lines. | 2014 |
2 |
| 16 |
23620486 | Application of receiver operating characteristic analysis to refine the prediction of potential digoxin drug interactions. | 2013 Jul |
1 |
| 17 |
23744557 | Interaction of CCN1 with αvβ3 integrin induces P-glycoprotein and confers vinblastine resistance in renal cell carcinoma cells. | 2013 Sep |
2 |
| 18 |
24062304 | P-glycoprotein mediates drug resistance via a novel mechanism involving lysosomal sequestration. | 2013 Nov 1 |
1 |
| 19 |
24335094 | Induction of the connexin 32 gene by epigallocatechin-3-gallate potentiates vinblastine-induced cytotoxicity in human renal carcinoma cells. | 2013 |
2 |
| 20 |
21618519 | Let-7 modulates acquired resistance of ovarian cancer to Taxanes via IMP-1-mediated stabilization of multidrug resistance 1. | 2012 Apr 15 |
1 |
| 21 |
22116711 | A new anticancer compound, oblongifolin C, inhibits tumor growth and promotes apoptosis in HeLa cells through Bax activation. | 2012 Sep 15 |
1 |
| 22 |
22258826 | The molecular interaction of a copper chelate with human P-glycoprotein. | 2012 May |
1 |
| 23 |
22727780 | Thiorhodamines containing amide and thioamide functionality as inhibitors of the ATP-binding cassette drug transporter P-glycoprotein (ABCB1). | 2012 Jul 15 |
2 |
| 24 |
22757751 | Overcoming multidrug-resistance in vitro and in vivo using the novel P-glycoprotein inhibitor 1416. | 2012 Dec |
1 |
| 25 |
21219884 | Molecular docking and pharmacogenomics of vinca alkaloids and their monomeric precursors, vindoline and catharanthine. | 2011 Mar 15 |
1 |
| 26 |
21262849 | Ixabepilone, a novel microtubule-targeting agent for breast cancer, is a substrate for P-glycoprotein (P-gp/MDR1/ABCB1) but not breast cancer resistance protein (BCRP/ABCG2). | 2011 May |
1 |
| 27 |
21514380 | Suppression of multidrug resistance by treatment with TRAIL in human ovarian and breast cancer cells with high level of c-Myc. | 2011 Jul |
1 |
| 28 |
21905209 | P-glycoprotein activity in human Caucasian male lymphocytes does not follow its increased expression during aging. | 2011 Nov |
1 |
| 29 |
21937435 | Conformational analysis of human ATP-binding cassette transporter ABCB1 in lipid nanodiscs and inhibition by the antibodies MRK16 and UIC2. | 2011 Nov 11 |
1 |
| 30 |
19631272 | Xenopus laevis oocytes expressing human P-glycoprotein: probing trans- and cis-inhibitory effects on [3H]vinblastine and [3H]digoxin efflux. | 2010 Jan |
4 |
| 31 |
20041327 | PXR-mediated induction of P-glycoprotein by anticancer drugs in a human colon adenocarcinoma-derived cell line. | 2010 Sep |
2 |
| 32 |
20118549 | Effects of dietary ingredients on function and expression of P-glycoprotein in human intestinal epithelial cells. | 2010 |
2 |
| 33 |
20135207 | Model analysis of the concentration-dependent permeability of P-gp substrates. | 2010 Mar |
4 |
| 34 |
20309692 | MDR1 C2005T polymorphism changes substrate specificity. | 2010 Aug |
2 |
| 35 |
20348394 | The antihelmintic flubendazole inhibits microtubule function through a mechanism distinct from Vinca alkaloids and displays preclinical activity in leukemia and myeloma. | 2010 Jun 10 |
2 |
| 36 |
20510207 | Up-regulation of connexin 32 gene by 5-aza-2'-deoxycytidine enhances vinblastine-induced cytotoxicity in human renal carcinoma cells via the activation of JNK signalling. | 2010 Aug 15 |
4 |
| 37 |
20590635 | Differences in the expression of endogenous efflux transporters in MDR1-transfected versus wildtype cell lines affect P-glycoprotein mediated drug transport. | 2010 Jul |
1 |
| 38 |
20595016 | Drug penetration model of vinblastine-treated Caco-2 cultures. | 2010 Sep 11 |
4 |
| 39 |
20623213 | A novel MDR1 GT1292-3TG (Cys431Leu) genetic variation and its effect on P-glycoprotein biologic functions. | 2010 Dec |
2 |
| 40 |
20663232 | TRAIL sensitize MDR cells to MDR-related drugs by down-regulation of P-glycoprotein through inhibition of DNA-PKcs/Akt/GSK-3beta pathway and activation of caspases. | 2010 Jul 28 |
1 |
| 41 |
20829196 | I-387, a novel antimitotic indole, displays a potent in vitro and in vivo antitumor activity with less neurotoxicity. | 2010 Nov |
1 |
| 42 |
22069634 | Overcoming multidrug resistance in human cancer cells by natural compounds. | 2010 Jun |
1 |
| 43 |
18946672 | Pediatric glioblastoma cell line shows different patterns of expression of transmembrane ABC transporters after in vitro exposure to vinblastine. | 2009 Jan |
2 |
| 44 |
19123050 | MDR1 (ABCB1) G1199A (Ser400Asn) polymorphism alters transepithelial permeability and sensitivity to anticancer agents. | 2009 Jun |
2 |
| 45 |
19530439 | Construction of a model cell line for the assay of MDR1 (multi drug resistance gene-1) substrates/inhibitors using HeLa cells. | 2009 May |
3 |
| 46 |
19631619 | Polarized P-glycoprotein expression by the immortalised human brain endothelial cell line, hCMEC/D3, restricts apical-to-basolateral permeability to rhodamine 123. | 2009 Oct 6 |
2 |
| 47 |
19777523 | Activators of P-glycoprotein: Structure-activity relationships and investigation of their mode of action. | 2009 Nov |
1 |
| 48 |
20024113 | Novel dihydro-beta-agarofuran sesquiterpenes as potent modulators of human P-glycoprotein dependent multidrug resistance. | 2009 Dec 21 |
1 |
| 49 |
18234154 | Inhibition of P-glycoprotein (ABCB1)- and multidrug resistance-associated protein 1 (ABCC1)-mediated transport by the orally administered inhibitor, CBT-1((R)). | 2008 Mar 15 |
1 |
| 50 |
18713316 | Polymorphisms within PfMDR1 alter the substrate specificity for anti-malarial drugs in Plasmodium falciparum. | 2008 Nov |
1 |