Oligonucleotides

ATP binding cassette subfamily B member 1 ; Homo sapiens







52 Article(s)
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1 34976439 Antisense oligonucleotide gapmers containing phosphoryl guanidine groups reverse MDR1-mediated multiple drug resistance of tumor cells. 2022 Mar 8 1
2 25801244 Inhibition of mdr1 by G-quadruplex oligonucleotides and reversal of paclitaxel resistance in human ovarian cancer cells. 2015 Aug 1
3 24637737 Reversing multidrug resistance in Caco-2 by silencing MDR1, MRP1, MRP2, and BCL-2/BCL-xL using liposomal antisense oligonucleotides. 2014 1
4 22955671 Single nucleotide polymorphism detection by optical DNA-based sensing coupled with whole genomic amplification. 2013 Jan 1
5 23418897 Involvement of c-Jun N-terminal kinase in reversal of multidrug resistance of human leukemia cells in hypoxia by 5-bromotetrandrine. 2013 Nov 2
6 22567180 ERCC1 C118T associates with response to FOLFOX4 chemotherapy in colorectal cancer patients in Han Chinese. 2012 2
7 19963040 Blood-brain barrier cell line PBMEC/C1-2 possesses functionally active P-glycoprotein. 2010 Jan 22 2
8 20137132 [Construction and identification of Mdr-1-shRNA eukaryotic expression vector]. 2010 Feb 1
9 20540746 Glucosylceramide synthase upregulates MDR1 expression in the regulation of cancer drug resistance through cSrc and beta-catenin signaling. 2010 Jun 11 1
10 18299310 Targeting MDR1 gene: synthesis and cellular study of modified daunomycin-triplex-forming oligonucleotide conjugates able to inhibit gene expression in resistant cell lines. 2008 May 1
11 17852455 Multidrug resistance inhibition by antisense oligonucleotide against MDR1/mRNA in P-glycoprotein expressing leukemic cells. 2007 Oct 2
12 18078069 [Study of the binding of nuclear proteins from Plasmodium berghei strains with different chloroquine sensitivity to oligonucleotides corresponding to regulatory elements of multidrug resistance (mdr1) gene]. 2007 Sep-Oct 3
13 16732907 [Reversion of multidrug resistance of hepatocellular carcinoma by antisense oligonucleotides and ultrasonic microbubble intensifier transfection combined with ultrasound irradiation]. 2006 May 1
14 16875601 [Reversion of multidrug resistance (MDR) in human glioma cells by RNA interference (RNAi)]. 2006 Mar 1
15 17038319 Fragmented hyaluronan induces transcriptional up-regulation of the multidrug resistance-1 gene in CD4+ T cells. 2006 Dec 8 1
16 17041234 Solution structure of a purine rich hexaloop hairpin belonging to PGY/MDR1 mRNA and targeted by antisense oligonucleotides. 2006 1
17 17147248 [Reversal of multi-drug resistance in K562/A02 cells by two short hairpin RNAs (shRNA) of mdr1]. 2006 Jul 1
18 15316104 Inhibition of MDR1 gene expression by chimeric HNA antisense oligonucleotides. 2004 1
19 15569157 Transcriptional regulation of multidrug resistance-1 gene by interleukin-2 in lymphocytes. 2004 Dec 1
20 12669953 Simultaneous modulation of multidrug resistance and antiapoptotic cellular defense by MDR1 and BCL-2 targeted antisense oligonucleotides enhances the anticancer efficacy of doxorubicin. 2003 Mar 1
21 11781249 P-glycoprotein-actin association through ERM family proteins: a role in P-glycoprotein function in human cells of lymphoid origin. 2002 Jan 15 3
22 11857396 In vitro and in vivo downregulation of MRP1 by antisense oligonucleotides: a potential role in neuroblastoma therapy. 2002 Mar 1 5
23 11948195 Evaluating the specificity of antisense oligonucleotide conjugates. A DNA array analysis. 2002 Jun 21 2
24 12031494 Downregulation of PGY1/MDR1 mRNA level in human KB cells by antisense oligonucleotide conjugates. RNA accessibility in vitro and intracellular antisense activity. 2002 Jun 7 9
25 12067980 Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene. 2002 Jun 15 3
26 12174371 Subcellular daunorubicin distribution and its relation to multidrug resistance phenotype in drug-resistant cell line SMMC-7721/R. 2002 Aug 1
27 11522831 5'-bis-pyrenylated oligonucleotides displaying excimer fluorescence provide sensitive probes of RNA sequence and structure. 2001 Sep 1 2
28 10565012 RNA mapping: selection of potent oligonucleotide sequences for antisense experiments. 2000 1
29 10783831 Modulation of multidrug resistance in human leukemia cells with mdr1-targeted antisense oligonucleotides using variable treatment schedules. 2000 Apr 1
30 10807948 Antisense inhibition of P-glycoprotein expression using peptide-oligonucleotide conjugates. 2000 Jul 1 2
31 10869552 Secondary structure of the 5'-region of PGY1/MDR1 mRNA. 2000 Jun 23 2
32 10369069 Increased AP-1 activity in drug resistant human breast cancer MCF-7 cells. 1999 Feb 2
33 10541289 Secretion of platelet-activating factor is mediated by MDR1 P-glycoprotein in cultured human mesangial cells. 1999 Nov 1
34 11798669 [Reversal of multidrug resistance of leukemia cell line in vitro by antisense phosphorothioate oligonucleotide]. 1999 Jun 1
35 9473242 Genetic polymorphism in MDR-1: a tool for examining allelic expression in normal cells, unselected and drug-selected cell lines, and human tumors. 1998 Mar 1 1
36 9558371 Inhibition of P-glycoprotein and recovery of drug sensitivity of human acute leukemic blast cells by multidrug resistance gene (mdr1) antisense oligonucleotides. 1998 May 1 4
37 9619752 Reversal of multidrug resistance by a liposome-MDR1 ribozyme complex. 1998 1
38 9627221 Cytometric study of intracellular P-gp expression and reversal of drug resistance. 1998 Jun 1 2
39 9655887 Novel chemically modified oligonucleotides provide potent inhibition of P-glycoprotein expression. 1998 Jul 3
40 9679161 Antisense to MDR1 mRNA reduces P-glycoprotein expression, swelling-activated C1- current and volume regulation in bovine ciliary epithelial cells. 1998 Aug 15 1
41 10076529 Requirement of expression of P-glycoprotein on human natural killer leukemia cells for cell-mediated cytotoxicity. 1998 May 1 2
42 9204974 Sensitization of multidrug-resistant human leukemia cells with MDR1-targeted antisense and inhibition of drug-mediated MDR1 induction. 1997 Jul 2
43 9209520 P-glycoprotein expression in cartilaginous tumors. 1997 Jun 1
44 8657572 Potent antisense oligonucleotides to the human multidrug resistance-1 mRNA are rationally selected by mapping RNA-accessible sites with oligonucleotide libraries. 1996 May 15 4
45 8819524 Cellular uptake mechanism for oligonucleotides: involvement of endocytosis in the uptake of phosphodiester oligonucleotides by a human colorectal adenocarcinoma cell line, HCT-15. 1996 Sep 1
46 8883415 mdm2 gene mediates the expression of mdr1 gene and P-glycoprotein in a human glioblastoma cell line. 1996 Oct 1
47 7499263 Volume-sensitive chloride channel activity does not depend on endogenous P-glycoprotein. 1995 Nov 17 2
48 7756675 Reversal of multiple drug resistance in vitro by phosphorothioate oligonucleotides and ribozymes. 1995 Feb 1
49 7526696 Expression and function of P-glycoprotein in human mesangial cells. 1994 Nov 1
50 7865906 Inhibition of MDR1 gene expression by antimessenger oligonucleotides lowers multiple drug resistance. 1994 1