| 101 |
29018094 | Substrate-induced conformational changes in the nucleotide-binding domains of lipid bilayer-associated P-glycoprotein during ATP hydrolysis. | 2017 Dec 15 |
3 |
| 102 |
29077148 | The effect of saikosaponin D on doxorubicin pharmacokinetics and its MDR reversal in MCF-7/adr cell xenografts. | 2017 Oct |
2 |
| 103 |
29145976 | Not only P-glycoprotein: Amplification of the ABCB1-containing chromosome region 7q21 confers multidrug resistance upon cancer cells by coordinated overexpression of an assortment of resistance-related proteins. | 2017 May |
3 |
| 104 |
26286835 | MDR1 polymorphisms have an impact on the prognosis of Chinese diffuse large B cell lymphoma patients. | 2016 Jan |
4 |
| 105 |
26553253 | Stereoselective Modulation of P-Glycoprotein by Chiral Small Molecules. | 2016 Jan 5 |
2 |
| 106 |
26704739 | Association of ABCB1 gene variants, plasma antidepressant concentration, and treatment response: Results from a randomized clinical study. | 2016 Feb |
2 |
| 107 |
26733176 | Targeting P-glycoprotein expression and cancer cell energy metabolism: combination of metformin and 2-deoxyglucose reverses the multidrug resistance of K562/Dox cells to doxorubicin. | 2016 Jul |
2 |
| 108 |
26902225 | Effects of Psoralen as an Anti-tumor Agent in Human Breast Cancer MCF-7/ADR Cells. | 2016 May 1 |
1 |
| 109 |
26932198 | Advances in plant-based inhibitors of P-glycoprotein. | 2016 Dec |
4 |
| 110 |
27117502 | A single active catalytic site is sufficient to promote transport in P-glycoprotein. | 2016 Apr 27 |
2 |
| 111 |
27175090 | The effect of ABCB1 polymorphisms on the outcome of breast cancer treatment. | 2016 |
2 |
| 112 |
27190212 | Cryo-EM Analysis of the Conformational Landscape of Human P-glycoprotein (ABCB1) During its Catalytic Cycle. | 2016 Jul |
6 |
| 113 |
27364832 | P-gp Inhibition-Based Strategies for Modulating Pharmacokinetics of Anticancer Drugs: An Update. | 2016 |
2 |
| 114 |
27531061 | Cooperativity between verapamil and ATP bound to the efflux transporter P-glycoprotein. | 2016 Oct 15 |
12 |
| 115 |
27785023 | Synergistic effects of A-B-C-type amphiphilic copolymer on reversal of drug resistance in MCF-7/ADR breast carcinoma. | 2016 |
3 |
| 116 |
30475507 | Substrate Specificity of Aglaia loheri Active Isolate towards P-glycoprotein in Multidrug-Resistant Cancer Cells. | 2016 Nov |
1 |
| 117 |
25234084 | P-glycoprotein induction in Caco-2 cells by newly synthetized thioxanthones prevents paraquat cytotoxicity. | 2015 Oct |
3 |
| 118 |
25435018 | Modulation of P-glycoprotein efflux pump: induction and activation as a therapeutic strategy. | 2015 May |
3 |
| 119 |
25450342 | Hydrogel-assisted functional reconstitution of human P-glycoprotein (ABCB1) in giant liposomes. | 2015 Feb |
2 |
| 120 |
25594233 | Demethoxycurcumin modulates human P-glycoprotein function via uncompetitive inhibition of ATPase hydrolysis activity. | 2015 Jan 28 |
1 |
| 121 |
25637762 | P-glycoprotein interactions of novel psychoactive substances - stimulation of ATP consumption and transport across Caco-2 monolayers. | 2015 Apr 1 |
3 |
| 122 |
25685543 | P-glycoprotein inhibitors of natural origin as potential tumor chemo-sensitizers: A review. | 2015 Jan |
4 |
| 123 |
25760620 | Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein. | 2015 Mar |
1 |
| 124 |
25801244 | Inhibition of mdr1 by G-quadruplex oligonucleotides and reversal of paclitaxel resistance in human ovarian cancer cells. | 2015 Aug |
2 |
| 125 |
25860377 | Impact of Genetic Polymorphisms of ABCB1 (MDR1, P-Glycoprotein) on Drug Disposition and Potential Clinical Implications: Update of the Literature. | 2015 Jul |
7 |
| 126 |
25869246 | In vitro effects of standardized extract of Bacopa monniera and its five individual active constituents on human P-glycoprotein activity. | 2015 |
1 |
| 127 |
25924616 | ATP-Binding Cassette Transporter Structure Changes Detected by Intramolecular Fluorescence Energy Transfer for High-Throughput Screening. | 2015 Jul |
1 |
| 128 |
25962593 | ATP-binding cassette subfamily B member 1 (ABCB1) and subfamily C member 10 (ABCC10) are not primary resistance factors for cabazitaxel. | 2015 Mar 5 |
1 |
| 129 |
25964294 | APO866 Increases Antitumor Activity of Cyclosporin-A by Inducing Mitochondrial and Endoplasmic Reticulum Stress in Leukemia Cells. | 2015 Sep 1 |
1 |
| 130 |
26012726 | Arylamino Esters As P-Glycoprotein Modulators: SAR Studies to Establish Requirements for Potency and Selectivity. | 2015 Aug |
1 |
| 131 |
26235354 | Reversal of P-glycoprotein-mediated multidrug resistance by the novel tetrandrine derivative W6. | 2015 |
2 |
| 132 |
26317651 | Afatinib reverses multidrug resistance in ovarian cancer via dually inhibiting ATP binding cassette subfamily B member 1. | 2015 Sep 22 |
1 |
| 133 |
26381710 | Allocrite Sensing and Binding by the Breast Cancer Resistance Protein (ABCG2) and P-Glycoprotein (ABCB1). | 2015 Oct 13 |
1 |
| 134 |
26516582 | In silico identified targeted inhibitors of P-glycoprotein overcome multidrug resistance in human cancer cells in culture. | 2015 Oct |
1 |
| 135 |
26558272 | Targeting Cellular Metabolism Chemosensitizes the Doxorubicin-Resistant Human Breast Adenocarcinoma Cells. | 2015 |
2 |
| 136 |
24107928 | Interaction of the efflux transporters ABCB1 and ABCG2 with imatinib, nilotinib, and dasatinib. | 2014 Mar |
2 |
| 137 |
24231430 | Differential functional rescue of Lys(513) and Lys(516) processing mutants of MRP1 (ABCC1) by chemical chaperones reveals different domain-domain interactions of the transporter. | 2014 Mar |
2 |
| 138 |
24256068 | Inhibition mechanism of P-glycoprotein mediated efflux by mPEG-PLA and influence of PLA chain length on P-glycoprotein inhibition activity. | 2014 Jan 6 |
2 |
| 139 |
24506763 | Reaction dynamics of ATP hydrolysis catalyzed by P-glycoprotein. | 2014 Feb 18 |
3 |
| 140 |
24613626 | Synthesis, biological evaluation and 3D-QSAR studies of new chalcone derivatives as inhibitors of human P-glycoprotein. | 2014 Apr 1 |
2 |
| 141 |
24632881 | Structural characterization of two metastable ATP-bound states of P-glycoprotein. | 2014 |
4 |
| 142 |
24643703 | Compounds from Chinese herbal medicines as reversal agents for P-glycoprotein-mediated multidrug resistance in tumours. | 2014 Jul |
3 |
| 143 |
24711707 | In silico structure-based screening of versatile P-glycoprotein inhibitors using polynomial empirical scoring functions. | 2014 |
4 |
| 144 |
24773054 | Design and synthesis of human ABCB1 (P-glycoprotein) inhibitors by peptide coupling of diverse chemical scaffolds on carboxyl and amino termini of (S)-valine-derived thiazole amino acid. | 2014 May 22 |
1 |
| 145 |
24897122 | Kinetic validation of the models for P-glycoprotein ATP hydrolysis and vanadate-induced trapping. Proposal for additional steps. | 2014 |
3 |
| 146 |
25016028 | The Q loops of the human multidrug resistance transporter ABCB1 are necessary to couple drug binding to the ATP catalytic cycle. | 2014 Oct |
3 |
| 147 |
25017650 | The novel bis-benzylisoquinoline PY35 reverses P-glycoprotein-mediated multidrug resistance. | 2014 Sep |
2 |
| 148 |
25169536 | Establishment and partial characterization of an epirubicin-resistant gastric cancer cell line with upregulated ABCB1. | 2014 |
3 |
| 149 |
25201738 | Enhanced effect of pH-sensitive mixed copolymer micelles for overcoming multidrug resistance of doxorubicin. | 2014 Dec |
2 |
| 150 |
25270578 | In silico screening for inhibitors of p-glycoprotein that target the nucleotide binding domains. | 2014 Dec |
3 |