| 51 |
33031417 | Human ABCB1 with an ABCB11-like degenerate nucleotide binding site maintains transport activity by avoiding nucleotide occlusion. | 2020 Oct |
3 |
| 52 |
33086089 | Downregulation of MDR 1 gene contributes to tyrosine kinase inhibitor induce apoptosis and reduction in tumor metastasis: A gravity to space investigation. | 2020 Dec 15 |
1 |
| 53 |
33168729 | Reversing the direction of drug transport mediated by the human multidrug transporter P-glycoprotein. | 2020 Nov 24 |
1 |
| 54 |
33312947 | Clinical Perspective of FDA Approved Drugs With P-Glycoprotein Inhibition Activities for Potential Cancer Therapeutics. | 2020 |
1 |
| 55 |
30390439 | Synthesis and biological evaluation of quinazoline derivatives - A SAR study of novel inhibitors of ABCG2. | 2019 Jan 1 |
1 |
| 56 |
30765569 | Structural insight into substrate and inhibitor discrimination by human P-glycoprotein. | 2019 Feb 15 |
1 |
| 57 |
30851394 | Large-scale purification of functional human P-glycoprotein (ABCB1). | 2019 Jul |
1 |
| 58 |
30899446 | An Energetically Favorable Ligand Entrance Gate of a Multidrug Transporter Revealed by Partial Nudged Elastic Band Simulations. | 2019 |
2 |
| 59 |
31097669 | Mechanism of allosteric modulation of P-glycoprotein by transport substrates and inhibitors. | 2019 May 17 |
2 |
| 60 |
31346154 | Influence of (ATP)-Binding Cassette Transporter Subfamily B Member 1 (ABCB1) Gene Polymorphism on the Efficacy of Remifentanil. | 2019 Jul 15 |
1 |
| 61 |
31465208 | Enhanced Reactive Oxygen Species Generation by Mitochondria Targeting of Anticancer Drug To Overcome Tumor Multidrug Resistance. | 2019 Oct 14 |
1 |
| 62 |
31585733 | Testosterone and androstenedione are endogenous substrates of P-glycoprotein. | 2019 Nov 26 |
1 |
| 63 |
31586724 | Near-infrared light switching nitric oxide nanoemitter for triple-combination therapy of multidrug resistant cancer. | 2019 Dec |
4 |
| 64 |
31641149 | Dynamics of ABC Transporter P-glycoprotein in Three Conformational States. | 2019 Oct 22 |
2 |
| 65 |
31702922 | Optimizing Targeted Inhibitors of P-Glycoprotein Using Computational and Structure-Guided Approaches. | 2019 Dec 12 |
2 |
| 66 |
31728254 | Incorporation of doxorubicin in different polymer nanoparticles and their anticancer activity. | 2019 |
1 |
| 67 |
31774117 | ATP-dependent thermostabilization of human P-glycoprotein (ABCB1) is blocked by modulators. | 2019 Dec 19 |
9 |
| 68 |
31810909 | Association of ABC Transporter With Resistance to FK866, a NAMPT Inhibitor, in Human Colorectal Cancer Cells. | 2019 Dec |
1 |
| 69 |
32254552 | Design of dual drug-loaded dendrimer/carbon dot nanohybrids for fluorescence imaging and enhanced chemotherapy of cancer cells. | 2019 Jan 14 |
1 |
| 70 |
28401939 | MDR1 deficiency impairs mitochondrial homeostasis and promotes intestinal inflammation. | 2018 Jan |
2 |
| 71 |
29155127 | MDR1 gene C3435T polymorphism in chronic hepatitis C patients. | 2018 Jan |
1 |
| 72 |
29290467 | ATP Binding Enables Substrate Release from Multidrug Resistance Protein 1. | 2018 Jan 11 |
1 |
| 73 |
29371429 | Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation. | 2018 Feb 23 |
2 |
| 74 |
29377455 | LysoTracker and MitoTracker Red are transport substrates of P-glycoprotein: implications for anticancer drug design evading multidrug resistance. | 2018 Apr |
2 |
| 75 |
29385210 | ABCC6 plays a significant role in the transport of nilotinib and dasatinib, and contributes to TKI resistance in vitro, in both cell lines and primary patient mononuclear cells. | 2018 |
1 |
| 76 |
29401431 | Dissecting the Forces that Dominate Dimerization of the Nucleotide Binding Domains of ABCB1. | 2018 Jan 23 |
1 |
| 77 |
29484528 | Variable Cell Line Pharmacokinetics Contribute to Non-Linear Treatment Response in Heterogeneous Cell Populations. | 2018 Jun |
2 |
| 78 |
29499278 | A Conformationally Gated Model of Methadone and Loperamide Transport by P-Glycoprotein. | 2018 Jul |
3 |
| 79 |
29511086 | Conformational dynamics of P-glycoprotein in lipid nanodiscs and detergent micelles reveal complex motions on a wide time scale. | 2018 Apr 27 |
1 |
| 80 |
29576448 | Dual inhibition of PI3K/mTOR signaling in chemoresistant AML primary cells. | 2018 May |
1 |
| 81 |
29599904 | Targeting multidrug-resistant ovarian cancer through estrogen receptor α dependent ATP depletion caused by hyperactivation of the unfolded protein response. | 2018 Mar 13 |
5 |
| 82 |
29723928 | Effect of ABCB1 C3435T Polymorphism on Pharmacokinetics of Antipsychotics and Antidepressants. | 2018 Oct |
2 |
| 83 |
29976562 | An Outward-Facing Aromatic Amino Acid Is Crucial for Signaling between the Membrane-Spanning and Nucleotide-Binding Domains of Multidrug Resistance Protein 1 (MRP1; ABCC1). | 2018 Sep |
1 |
| 84 |
30037151 | Theoretical Prediction of the Complex P-Glycoprotein Substrate Efflux Based on the Novel Hierarchical Support Vector Regression Scheme. | 2018 Jul 22 |
2 |
| 85 |
30052463 | Novel Potent ABCB1 Modulator, Phenethylisoquinoline Alkaloid, Reverses Multidrug Resistance in Cancer Cell. | 2018 Sep 4 |
2 |
| 86 |
30121251 | The conformation and dynamics of P-glycoprotein in a lipid bilayer investigated by atomic force microscopy. | 2018 Oct |
2 |
| 87 |
30143707 | Mapping discontinuous epitopes for MRK-16, UIC2 and 4E3 antibodies to extracellular loops 1 and 4 of human P-glycoprotein. | 2018 Aug 24 |
2 |
| 88 |
30279588 | Allosteric Role of Substrate Occupancy Toward the Alignment of P-glycoprotein Nucleotide Binding Domains. | 2018 Oct 2 |
2 |
| 89 |
30412370 | The importance of the polymorphisms of the ABCB1 gene in disease susceptibility, behavior and response to treatment in inflammatory bowel disease: A literature review. | 2018 Oct |
4 |
| 90 |
30463238 | pH-Sensitive Poly(β-amino ester)s Nanocarriers Facilitate the Inhibition of Drug Resistance in Breast Cancer Cells. | 2018 Nov 19 |
2 |
| 91 |
30497065 | Targeting P-Glycoprotein: Nelfinavir Reverses Adriamycin Resistance in K562/ADR Cells. | 2018 |
1 |
| 92 |
31223218 | Genomic amplification of chromosome 7 in the Doxorubicin resistant K562 cell line. | 2018 |
1 |
| 93 |
27956367 | Systematic evaluation of multifunctional paclitaxel-loaded polymeric mixed micelles as a potential anticancer remedy to overcome multidrug resistance. | 2017 Mar 1 |
2 |
| 94 |
28283434 | Insights Into the Molecular Mechanism of Triptan Transport by P-glycoprotein. | 2017 Jun |
7 |
| 95 |
28283574 | Effects of a detergent micelle environment on P-glycoprotein (ABCB1)-ligand interactions. | 2017 Apr 28 |
2 |
| 96 |
28289287 | Energy transduction and alternating access of the mammalian ABC transporter P-glycoprotein. | 2017 Mar 30 |
2 |
| 97 |
28587082 | Natural Products as Alternative Choices for P-Glycoprotein (P-gp) Inhibition. | 2017 May 25 |
2 |
| 98 |
28728917 | Global alteration of the drug-binding pocket of human P-glycoprotein (ABCB1) by substitution of fifteen conserved residues reveals a negative correlation between substrate size and transport efficiency. | 2017 Nov 1 |
3 |
| 99 |
28837794 | A short cross-linker activates human P-glycoprotein missing a catalytic carboxylate. | 2017 Dec 1 |
3 |
| 100 |
28915956 | Dual inhibition of P-glycoprotein and midkine may increase therapeutic effects of anticancer drugs. | 2017 Sep |
2 |