Tryptophan

ATP binding cassette subfamily B member 1 ; Homo sapiens







13 Article(s)
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1 35634783 Structure-based alteration of tryptophan residues of the multidrug transporter CmABCB1 to assess substrate binding using fluorescence spectroscopy. 2022 Jun 2
2 29499278 A Conformationally Gated Model of Methadone and Loperamide Transport by P-Glycoprotein. 2018 Jul 1
3 19398503 Molecular basis for reduced estrone sulfate transport and altered modulator sensitivity of transmembrane helix (TM) 6 and TM17 mutants of multidrug resistance protein 1 (ABCC1). 2009 Jul 1
4 19818729 Interaction of LDS-751 with the drug-binding site of P-glycoprotein: a Trp fluorescence steady-state and lifetime study. 2009 Dec 2
5 16919386 Sensitivity of P-glycoprotein tryptophan residues to benzodiazepines and ATP interaction. 2007 Jan 1
6 17257580 The predicted transmembrane fragment 17 of the human multidrug resistance protein 1 (MRP1) behaves as an interfacial helix in membrane mimics. 2007 Mar 1
7 17490606 Interaction of insecticides with mammalian P-glycoprotein and their effect on its transport function. 2007 Jul 1
8 15641790 Interaction of LDS-751 with P-glycoprotein and mapping of the location of the R drug binding site. 2005 Jan 18 1
9 11925441 Determinants of the substrate specificity of multidrug resistance protein 1: role of amino acid residues with hydrogen bonding potential in predicted transmembrane helix 17. 2002 Jun 7 1
10 12034727 GSH-dependent photolabeling of multidrug resistance protein MRP1 (ABCC1) by [125I]LY475776. Evidence of a major binding site in the COOH-proximal membrane spanning domain. 2002 Aug 9 1
11 11278867 Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport. 2001 May 11 1
12 11101309 Intrinsic fluorescence of the P-glycoprotein multidrug transporter: sensitivity of tryptophan residues to binding of drugs and nucleotides. 2000 Dec 5 3
13 10364203 Ligand-mediated tertiary structure changes of reconstituted P-glycoprotein. A tryptophan fluorescence quenching analysis. 1999 Jun 18 1