| 1 |
34380995 | Pharmacogenetic study of methadone treatment for heroin addiction: associations between drug-metabolizing gene polymorphisms and treatment efficacy. | 2022 Jan 1 |
2 |
| 2 |
32841585 | Pharmacogenomics biomarkers for personalized methadone maintenance treatment: The mechanism and its potential use. | 2021 Apr 1 |
2 |
| 3 |
33454797 | Brain/blood ratios of methadone and ABCB1 polymorphisms in methadone-related deaths. | 2021 Mar |
5 |
| 4 |
32705966 | Pharmacogenomics of methadone: a narrative review of the literature. | 2020 Aug |
1 |
| 5 |
33410778 | ABCB1, CYP2B6, and CYP3A4 genetic polymorphisms do not affect methadone maintenance treatment in HCV-positive patients. | 2020 Dec 31 |
1 |
| 6 |
29499278 | A Conformationally Gated Model of Methadone and Loperamide Transport by P-Glycoprotein. | 2018 Jul |
8 |
| 7 |
28252574 | ABCB1 Polymorphisms and Cold Pressor Pain Responses: Opioid-Dependent Patients on Methadone Maintenance Therapy. | 2017 Mar/Apr |
8 |
| 8 |
28867064 | Increased DNA Methylation of ABCB1, CYP2D6, and OPRM1 Genes in Newborn Infants of Methadone-Maintained Opioid-Dependent Mothers. | 2017 Nov |
1 |
| 9 |
29173032 | Impact of SNP-SNP interaction among ABCB1, ARRB2, DRD1 and OPRD1 on methadone dosage requirement in Han Chinese patients. | 2017 Dec |
5 |
| 10 |
27061230 | The ABCB1, rs9282564, AG and TT Genotypes and the COMT, rs4680, AA Genotype are Less Frequent in Deceased Patients with Opioid Addiction than in Living Patients with Opioid Addiction. | 2016 Oct |
3 |
| 11 |
27284701 | Relationship between ABCB1 polymorphisms and serum methadone concentration in patients undergoing methadone maintenance therapy (MMT). | 2016 Sep |
9 |
| 12 |
27286724 | Population Genetic-Based Pharmacokinetic Modeling of Methadone and its Relationship with the QTc Interval in Opioid-Dependent Patients. | 2016 Dec |
1 |
| 13 |
24489693 | Impact of ABCB1 and CYP2B6 genetic polymorphisms on methadone metabolism, dose and treatment response in patients with opioid addiction: a systematic review and meta-analysis. | 2014 |
2 |
| 14 |
25072223 | Cyclosporine-inhibitable cerebral drug transport does not influence clinical methadone pharmacodynamics. | 2014 Dec |
2 |
| 15 |
21790905 | CYP2B6 SNPs are associated with methadone dose required for effective treatment of opioid addiction. | 2013 Jul |
1 |
| 16 |
23527191 | Functional impact of ABCB1 variants on interactions between P-glycoprotein and methadone. | 2013 |
6 |
| 17 |
24455721 | Moving toward personalized medicine in the methadone maintenance treatment program: a pilot study on the evaluation of treatment responses in Taiwan. | 2013 |
1 |
| 18 |
23226062 | ABCB1 haplotype and OPRM1 118A > G genotype interaction in methadone maintenance treatment pharmacogenetics. | 2012 |
6 |
| 19 |
21589866 | Contribution of cytochrome P450 and ABCB1 genetic variability on methadone pharmacokinetics, dose requirements, and response. | 2011 May 12 |
1 |
| 20 |
21827411 | Opioid transport by ATP-binding cassette transporters at the blood-brain barrier: implications for neuropsychopharmacology. | 2011 |
1 |
| 21 |
21902500 | Impact of genetic polymorphisms in ABCB1, CYP2B6, OPRM1, ANKK1 and DRD2 genes on methadone therapy in Han Chinese patients. | 2011 Nov |
3 |
| 22 |
19887017 | Interaction of drugs of abuse and maintenance treatments with human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2). | 2010 Aug |
3 |
| 23 |
18166326 | Transfer of methadone across the dually perfused preterm human placental lobule. | 2008 Jan |
1 |
| 24 |
18422375 | Interindividual variability of methadone response: impact of genetic polymorphism. | 2008 |
3 |
| 25 |
18424454 | ABCB1 (MDR1) genetic variants are associated with methadone doses required for effective treatment of heroin dependence. | 2008 Jul 15 |
9 |
| 26 |
17502774 | Increased (R)-methadone plasma concentrations by quetiapine in cytochrome P450s and ABCB1 genotyped patients. | 2007 Jun |
2 |
| 27 |
17690563 | In vitro P-glycoprotein-mediated transport of (R)-, (S)-, (R,S)-methadone, LAAM and their main metabolites. | 2007 |
2 |
| 28 |
16837625 | In vivo activation of human pregnane X receptor tightens the blood-brain barrier to methadone through P-glycoprotein up-regulation. | 2006 Oct |
1 |
| 29 |
17178267 | ABCB1 and cytochrome P450 genotypes and phenotypes: influence on methadone plasma levels and response to treatment. | 2006 Dec |
3 |
| 30 |
17178268 | ABCB1 genetic variability and methadone dosage requirements in opioid-dependent individuals. | 2006 Dec |
4 |
| 31 |
15876424 | Role of P-glycoprotein in transplacental transfer of methadone. | 2005 Jun 15 |
7 |
| 32 |
15089813 | The effect of quinidine, used as a probe for the involvement of P-glycoprotein, on the intestinal absorption and pharmacodynamics of methadone. | 2004 May |
7 |
| 33 |
11408360 | Methadone inhibits rhodamine123 transport in Caco-2 cells. | 2001 Jul |
4 |