Etoposide

ATP binding cassette subfamily B member 1 ; Homo sapiens







113 Article(s)
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51 16478794 MDR1 polymorphisms predict the response to etoposide-cisplatin combination chemotherapy in small cell lung cancer. 2006 Mar 2
52 16964701 [Is MDR 1 gene a key to successful chemotherapy?]. 2006 Jun 1
53 15617835 Potentiation by alpha-tocopheryl succinate of the etoposide response in multidrug resistance protein 1-expressing glioblastoma cells. 2005 Jan 20 3
54 15999103 Combined effects of GSTP1 and MRP1 in melanoma drug resistance. 2005 Jul 25 1
55 16023314 A combined cell based approach to identify P-glycoprotein substrates and inhibitors in a single assay. 2005 Sep 14 1
56 14726695 Overexpression of ZNRD1 promotes multidrug-resistant phenotype of gastric cancer cells through upregulation of P-glycoprotein. 2004 Apr 1
57 15049699 Improved energy coupling of human P-glycoprotein by the glycine 185 to valine mutation. 2004 Apr 6 2
58 15590186 Multidrug-resistant hela cells overexpressing MRP1 exhibit sensitivity to cell killing by hyperthermia: interactions with etoposide. 2004 Dec 1 2
59 12948018 Efflux ratio cannot assess P-glycoprotein-mediated attenuation of absorptive transport: asymmetric effect of P-glycoprotein on absorptive and secretory transport across Caco-2 cell monolayers. 2003 Aug 1
60 11901101 Delineating the contribution of secretory transporters in the efflux of etoposide using Madin-Darby canine kidney (MDCK) cells overexpressing P-glycoprotein (Pgp), multidrug resistance-associated protein (MRP1), and canalicular multispecific organic anion transporter (cMOAT). 2002 Apr 1
61 12516967 Identification and characterization of the canine multidrug resistance-associated protein. 2002 Dec 1
62 11284689 Coordinate changes in drug resistance and drug-induced conformational transitions in altered-function mutants of the multidrug transporter P-glycoprotein. 2001 Apr 10 1
63 11473730 A new quinoline derivative MS-209 reverses multidrug resistance and inhibits multiorgan metastases by P-glycoprotein-expressing human small cell lung cancer cells. 2001 Jul 1
64 11486401 DICE (dexamethasone, ifosfamide, cisplatin, etoposide) infusional chemotherapy for refractory or relapsed non-Hodgkin's lymphoma (NHL). 2001 Jul 1
65 11504821 Multidrug resistance-associated protein-1 functional activity in Calu-3 cells. 2001 Sep 4
66 11595714 In vitro prevention of the emergence of multidrug resistance in a pediatric rhabdomyosarcoma cell line. 2001 Oct 2
67 10747957 Nonequivalent nucleotide trapping in the two nucleotide binding folds of the human multidrug resistance protein MRP1. 2000 Jun 9 3
68 10755319 Effect of high-dose cyclosporine on etoposide pharmacodynamics in a trial to reverse P-glycoprotein (MDR1 gene) mediated drug resistance. 2000 3
69 10912951 Growth inhibitory effect of a new camptothecin analog, DX-8951f, on various drug-resistant sublines including BCRP-mediated camptothecin derivative-resistant variants derived from the human lung cancer cell line PC-6. 2000 Jun 3
70 9864431 The chemosensitizing potential of GF120918 is independent of the magnitude of P-glycoprotein-mediated resistance to conventional chemotherapeutic agents in a small cell lung cancer line. 1999 Jan-Feb 6
71 10233413 Etoposide-induced DNA strand breaks in relation to p-glycoprotein and topoisomerase II protein expression in leukaemic cells from patients with AML and CLL. 1999 May 1
72 10561359 Parallel phase I studies of daunorubicin given with cytarabine and etoposide with or without the multidrug resistance modulator PSC-833 in previously untreated patients 60 years of age or older with acute myeloid leukemia: results of cancer and leukemia group B study 9420. 1999 Sep 1
73 10576649 The acridonecarboxamide GF120918 potently reverses P-glycoprotein-mediated resistance in human sarcoma MES-Dx5 cells. 1999 Nov 2
74 9485370 Kinetic analysis of calcein and calcein-acetoxymethylester efflux mediated by the multidrug resistance protein and P-glycoprotein. 1998 Feb 24 1
75 9504636 MDR1 gene expression and drug resistance of AML cells. 1998 Mar 2
76 9649010 Relatively low expression of multidrug resistance-1 (MDR-1) and its possible clinical implication in gastric cancers. 1998 Jun 1
77 9652763 Immunohistochemical detection of DNA topoisomerase IIalpha, P-glycoprotein and multidrug resistance protein (MRP) in small-cell and non-small-cell lung cancer. 1998 May 1
78 9685354 Coordinated action of glutathione S-transferases (GSTs) and multidrug resistance protein 1 (MRP1) in antineoplastic drug detoxification. Mechanism of GST A1-1- and MRP1-associated resistance to chlorambucil in MCF7 breast carcinoma cells. 1998 Aug 7 1
79 9780138 Therapeutic approach to drug resistant tumors. 1998 Oct 1
80 9155147 [Multidrug resistance of cancer cells mediated by ABC superfamily transporters]. 1997 May 1
81 9220975 Alteration of substrate specificity by mutations at the His61 position in predicted transmembrane domain 1 of human MDR1/P-glycoprotein. 1997 Jul 22 1
82 9272128 Modulation and prevention of multidrug resistance by inhibitors of P-glycoprotein. 1997 1
83 9272134 Treatment for adult T-cell leukemia. 1997 1
84 9350240 [Expression of ATP binding cassette superfamily (multidrug resistance-1, multidrug resistance-associated protein, human canalicular multispecific organ anion transporter) mRNA in etoposide and m-AMSA resistant cell lines]. 1997 Oct 1
85 9353133 P-glycoprotein-independent decrease in drug accumulation by phorbol ester treatment of tumor cells. 1997 Oct 1 2
86 9377550 Loss of amino acids 1490Lys-Ser-Lys1492 in the COOH-terminal region of topoisomerase IIalpha in human small cell lung cancer cells selected for resistance to etoposide results in an extranuclear enzyme localization. 1997 Oct 15 1
87 9639738 [The relationship between multi-drug resistance gene expression and drug resistance of ovarian carcinoma]. 1997 Aug 1
88 8567633 Altered drug-stimulated ATPase activity in mutants of the human multidrug resistance protein. 1996 Jan 26 1
89 8612315 Reversal of doxorubicin, etoposide, vinblastine, and taxol resistance in multidrug resistant human sarcoma cells by a polymer of spermine. 1996 1
90 8640766 Resistance mechanisms in human sarcoma mutants derived by single-step exposure to paclitaxel (Taxol). 1996 Mar 1 1
91 9042212 Differential interactions of Pgp inhibitor thaliblastine with adriamycin, etoposide, taxol and anthrapyrazole CI941 in sensitive and multidrug-resistant human MCF-7 breast cancer cells. 1996 Nov-Dec 1
92 7492789 Anti-B4-blocked ricin synergizes with doxorubicin and etoposide on multidrug-resistant and drug-sensitive tumors. 1995 Dec 1 1
93 7670142 Development of drug resistance is reduced with idarubicin relative to other anthracyclines. 1995 Jun 1
94 7834606 Sequential coexpression of the multidrug resistance genes MRP and mdr1 and their products in VP-16 (etoposide)-selected H69 small cell lung cancer cells. 1995 Feb 1 1
95 7705462 Dexniguldipine-HCl is a potent allosteric inhibitor of [3H]vinblastine binding to P-glycoprotein of CCRF ADR 5000 cells. 1994 Dec 15 2
96 7914749 Clinical importance of P-glycoprotein-related resistance in leukemia and myelodysplastic syndromes--first experience with their reversal. 1994 1
97 8028036 Mutation rates and mechanisms of resistance to etoposide determined from fluctuation analysis. 1994 Aug 3 1
98 8070020 Etoposide: current status and future perspectives in the management of malignant neoplasms. 1994 2
99 8100862 Evaluation of multiple drug resistance in human bladder cancer cell lines. 1993 Aug 1
100 8106148 Reversal of etoposide resistance in non-P-glycoprotein expressing multidrug resistant tumor cell lines by novobiocin. 1993 Nov 15 1