Etoposide

ATP binding cassette subfamily B member 1 ; Homo sapiens







113 Article(s)
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1 33627632 Mutant p53 promotes RCP-dependent chemoresistance coinciding with increased delivery of P-glycoprotein to the plasma membrane. 2021 Feb 24 1
2 33952826 Rapid Increase of Gastrointestinal P-Glycoprotein Functional Activity in Response to Etoposide Stimulation. 2021 7
3 30650062 MDR1 inhibition increases sensitivity to doxorubicin and etoposide in adrenocortical cancer. 2019 Mar 3
4 30977678 ABCB1 (C1236T) Polymorphism Affects P-Glycoprotein-Mediated Transport of Methotrexate, Doxorubicin, Actinomycin D, and Etoposide. 2019 May 8
5 31311995 A role for ABCB1 in prognosis, invasion and drug resistance in ependymoma. 2019 Jul 16 1
6 27926506 Disruption of the association between drug transporter and actin cytoskeleton abolishes drug resistance in hypertrophic scar. 2017 Jan 10 1
7 28070169 Overexpression of trefoil factor 3 (TFF3) contributes to the malignant progression in cervical cancer cells. 2017 2
8 28291743 Lactobionic acid-conjugated TPGS nanoparticles for enhancing therapeutic efficacy of etoposide against hepatocellular carcinoma. 2017 May 12 1
9 28587395 Effectiveness of imatinib mesylate over etoposide in the treatment of sensitive and resistant chronic myeloid leukaemia cells in vitro. 2017 Jun 1
10 26548759 Targeting ABCB1 and ABCC1 with their Specific Inhibitor CBT-1® can Overcome Drug Resistance in Osteosarcoma. 2016 1
11 26827764 ABCB5-Targeted Chemoresistance Reversal Inhibits Merkel Cell Carcinoma Growth. 2016 Apr 1
12 27570640 Transient resistance to DNA damaging agents is associated with expression of microRNAs-135b and -196b in human leukemia cell lines. 2016 1
13 27840903 Low dose of arsenic trioxide inhibits multidrug resistant-related P-glycoprotein expression in human neuroblastoma cell line. 2016 Dec 1
14 32263493 Overcoming multidrug resistance by a combination of chemotherapy and photothermal therapy mediated by carbon nanohorns. 2016 Sep 28 2
15 25395162 Upregulation of Stat1-HDAC4 confers resistance to etoposide through enhanced multidrug resistance 1 expression in human A549 lung cancer cells. 2015 Mar 1
16 25866761 Thyroid hormone and P-glycoprotein in tumor cells. 2015 1
17 25901027 Circadian modulation in the intestinal absorption of P-glycoprotein substrates in monkeys. 2015 Jul 2
18 25948303 [Role of Scaffold Proteins in Functional Alteration of Small Intestinal P-glycoprotein by Anti-cancer Drugs]. 2015 5
19 26136652 Inhibition of multidrug resistance protein 1 (MRP1) improves chemotherapy drug response in primary and recurrent glioblastoma multiforme. 2015 3
20 26153782 P-glycoprotein is expressed and causes resistance to chemotherapy in EBV-positive T-cell lymphoproliferative diseases. 2015 Oct 1
21 26463638 Reversal of chemoresistance with small interference RNA (siRNA) in etoposide resistant acute myeloid leukemia cells (HL-60). 2015 Oct 4
22 26515462 Etoposide enhances antitumor efficacy of MDR1-driven oncolytic adenovirus through autoupregulation of the MDR1 promoter activity. 2015 Nov 10 2
23 24220725 Extract of Bryophyllum laetivirens reverses etoposide resistance in human lung A549 cancer cells by downregulation of NF-κB. 2014 Jan 1
24 24868599 FTY720 enhances chemosensitivity of colon cancer cells to doxorubicin and etoposide via the modulation of P-glycoprotein and multidrug resistance protein 1. 2014 May 2
25 24882643 [Effect of repeated oral treatment with etoposide on the expression of intestinal P-glycoprotein and oral morphine analgesia]. 2014 6
26 24887326 Overcoming multiple drug resistance mechanisms in medulloblastoma. 2014 May 30 2
27 24989004 Changes in PtdIns(4,5)P2 induced by etoposide treatment modulates small intestinal P-glycoprotein via radixin. 2014 6
28 25087953 Schedule-dependent cytotoxicity of Etoposide and cyclophosphamide in P-glycoprotein-expressing human leukemic K-562 cells. 2014 1
29 23254912 Effects of morin on the pharmacokinetics of etoposide in 7,12-dimethylbenz[a]anthracene-induced mammary tumors in female Sprague-Dawley rats. 2013 Mar 2
30 23303573 Activation of ERM-family proteins via RhoA-ROCK signaling increases intestinal P-gp expression and leads to attenuation of oral morphine analgesia. 2013 Mar 5
31 23508810 Time-dependent changes in the activation of RhoA/ROCK and ERM/p-ERM in the increased expression of intestinal P-glycoprotein by repeated oral treatment with etoposide. 2013 May 6
32 23909136 Self-nanoemulsifying lipid carrier system for enhancement of oral bioavailability of etoposide by P-glycoprotein modulation: in vitro cell line and in vivo pharmacokinetic investigation. 2013 Jul 3
33 23981337 Enhanced intestinal absorption of etoposide by self-microemulsifying drug delivery systems: roles of P-glycoprotein and cytochrome P450 3A inhibition. 2013 Nov 20 5
34 24189426 Radixin influences the changes in the small intestinal P-glycoprotein by etoposide treatment. 2013 7
35 22116711 A new anticancer compound, oblongifolin C, inhibits tumor growth and promotes apoptosis in HeLa cells through Bax activation. 2012 Sep 15 1
36 22420656 Etoposide modulates the effects of oral morphine analgesia by targeting the intestinal P-glycoprotein. 2012 Apr 7
37 22543673 Predictive value of ABCB1 polymorphisms G2677T/A, C3435T, and their haplotype in small cell lung cancer patients treated with chemotherapy. 2012 Sep 1
38 22982667 RhoA affects oral morphine analgesia depending on functional variation in intestinal P-glycoprotein induced by repeated etoposide treatment. 2012 Dec 18 9
39 20856196 Human AP endonuclease (APE1/Ref-1) and its acetylation regulate YB-1-p300 recruitment and RNA polymerase II loading in the drug-induced activation of multidrug resistance gene MDR1. 2011 Jan 27 1
40 21356302 Enhancing effect of N-octyl-O-sulfate chitosan on etoposide absorption. 2011 May 16 2
41 21498714 Overcoming multidrug resistance in human lung cancer with novel benzo[a]quinolizin-4-ones. 2011 Mar 2
42 21514380 Suppression of multidrug resistance by treatment with TRAIL in human ovarian and breast cancer cells with high level of c-Myc. 2011 Jul 1
43 19817749 Increased chemoresistance induced by inhibition of HIF-prolyl-hydroxylase domain enzymes. 2010 Jan 1
44 20309692 MDR1 C2005T polymorphism changes substrate specificity. 2010 Aug 1
45 19723047 Inhibition of P-glycoprotein by wogonin is involved with the potentiation of etoposide-induced apoptosis in cancer cells. 2009 Aug 1
46 19725578 Modulation of multidrug resistance protein 1 (MRP1/ABCC1)-mediated multidrug resistance by bivalent apigenin homodimers and their derivatives. 2009 Sep 10 2
47 18282684 Inhibition of MDR1 expression by retinol treatment increases sensitivity to etoposide (VP16) in human neoplasic cell line. 2008 Jun 2
48 18723777 A novel human multidrug resistance gene MDR1 variant G571A (G191R) modulates cancer drug resistance and efflux transport. 2008 Nov 1
49 17279585 Expression levels and activation of a PXR variant are directly related to drug resistance in osteosarcoma cell lines. 2007 Mar 1 1
50 17351391 Correlations between the activities of 19 standard anticancer agents, antioxidative enzyme activities and the expression of ATP-binding cassette transporters: comparison with the National Cancer Institute data. 2007 Apr 1