| 201 |
22405646 | Synthesis and biological evaluation of novel bifendate derivatives bearing 6,7-dihydro-dibenzo[c,e]azepine scaffold as potent P-glycoprotein inhibitors. | 2012 May |
1 |
| 202 |
22411726 | Intestinal transport of pure diester-type alkaloids from an aconite extract across the Caco-2 cell monolayer model. | 2012 May |
1 |
| 203 |
22545578 | Up-regulation of P-glycoprotein is involved in the increased paclitaxel resistance in human esophageal cancer radioresistant cells. | 2012 Jul |
1 |
| 204 |
22584255 | Inhibition of P-glycoprotein leads to improved oral bioavailability of compound K, an anticancer metabolite of red ginseng extract produced by gut microflora. | 2012 Aug |
2 |
| 205 |
22588188 | No evidence for additional blood-brain barrier P-glycoprotein dysfunction in Alzheimer's disease patients with microbleeds. | 2012 Aug |
2 |
| 206 |
22734651 | Development of peptide-based reversing agents for p-glycoprotein-mediated resistance to carfilzomib. | 2012 Aug 6 |
1 |
| 207 |
22764578 | Blood-brain barrier in vitro models as tools in drug discovery: assessment of the transport ranking of antihistaminic drugs. | 2012 May |
3 |
| 208 |
22792804 | [Effect of Shaoyao Gancao Tang on function and expression of P-glycoprotein in Caco-2 cells]. | 2012 Apr |
4 |
| 209 |
23046348 | BBA, a derivative of 23-hydroxybetulinic acid, potently reverses ABCB1-mediated drug resistance in vitro and in vivo. | 2012 Nov 5 |
1 |
| 210 |
23072916 | Intestinal permeability of lamivudine (3TC) and two novel 3TC prodrugs. Experimental and theoretical analyses. | 2012 Dec 18 |
2 |
| 211 |
23134497 | P-glycoprotein imaging in temporal lobe epilepsy: in vivo PET experiments with the Pgp substrate [11C]-verapamil. | 2012 Nov |
3 |
| 212 |
23519262 | Absorption and interaction of the main constituents from the traditional Chinese drug pair Shaoyao-Gancao via a Caco-2 cell monolayer model. | 2012 Dec 13 |
3 |
| 213 |
20563580 | Effect of MDR modulators verapamil and promethazine on gene expression levels of MDR1 and MRP1 in doxorubicin-resistant MCF-7 cells. | 2011 Apr |
3 |
| 214 |
20824508 | Assessing p-glycoprotein (Pgp) activity in vivo utilizing 68Ga-Schiff base complexes. | 2011 Oct |
3 |
| 215 |
21062675 | Reversion of resistance to immunosuppressive agents in three patients with psoriatic arthritis by cyclosporine A: modulation of P-glycoprotein function. | 2011 Jan |
2 |
| 216 |
21128075 | Over-expression of MDR1 in amrubicinol-resistant lung cancer cells. | 2011 Sep |
1 |
| 217 |
21229388 | Influence of P-glycoprotein on embryotoxicity of the antifouling biocides to sea urchin (Strongylocentrotus intermedius). | 2011 Mar |
2 |
| 218 |
21289467 | Upregulation of P-glycoprotein activity in porcine oocytes and granulosa cells during in vitro maturation. | 2011 Jun |
2 |
| 219 |
21308736 | Euphorbia factor L1 reverses ABCB1-mediated multidrug resistance involving interaction with ABCB1 independent of ABCB1 downregualtion. | 2011 Apr |
1 |
| 220 |
21336515 | Assessment and modulation of phillyrin absorption by P-gp using Caco-2 cells and MDR1-MDCKII cells. | 2011 Mar |
1 |
| 221 |
21336967 | P-glycoprotein enhances radiation-induced apoptotic cell death through the regulation of miR-16 and Bcl-2 expressions in hepatocellular carcinoma cells. | 2011 May |
3 |
| 222 |
21371443 | A unique P-glycoprotein interacting agent displays anticancer activity against hepatocellular carcinoma through inhibition of GRP78 and mTOR pathways. | 2011 May 1 |
2 |
| 223 |
21439263 | On-line identification of P-glycoprotein substrates by monitoring of extracellular acidification and respiration rates in living cells. | 2011 Jul |
2 |
| 224 |
21440934 | The mechanism of enhancement on oral absorption of paclitaxel by N-octyl-O-sulfate chitosan micelles. | 2011 Jul |
1 |
| 225 |
21491921 | Liposome-encapsulated doxorubicin reverses drug resistance by inhibiting P-glycoprotein in human cancer cells. | 2011 Jun 6 |
1 |
| 226 |
21538216 | Resistance to the translation initiation inhibitor silvestrol is mediated by ABCB1/P-glycoprotein overexpression in acute lymphoblastic leukemia cells. | 2011 Sep |
1 |
| 227 |
21589945 | Exhaustive sampling of docking poses reveals binding hypotheses for propafenone type inhibitors of P-glycoprotein. | 2011 May |
1 |
| 228 |
21634011 | Identification of xanthones as selective killers of cancer cells overexpressing the ABC transporter MRP1. | 2011 Aug 1 |
1 |
| 229 |
21636258 | Regulation of endocytosis into human brain-microvascular endothelial cells by inhibition of efflux proteins. | 2011 Oct 1 |
2 |
| 230 |
21692796 | In vitro transport profile of carbamazepine, oxcarbazepine, eslicarbazepine acetate, and their active metabolites by human P-glycoprotein. | 2011 Oct |
1 |
| 231 |
21716273 | Nonlinear pharmacokinetics of oral quinidine and verapamil in healthy subjects: a clinical microdosing study. | 2011 Aug |
2 |
| 232 |
21721007 | Poor oral bioavailability of a promising anticancer agent andrographolide is due to extensive metabolism and efflux by P-glycoprotein. | 2011 Nov |
2 |
| 233 |
21733412 | Exposure of LS-180 cells to drugs of diverse physicochemical and therapeutic properties up-regulates P-glycoprotein expression and activity. | 2011 |
1 |
| 234 |
21757611 | Enhancement of oral bioavailability of 20(S)-ginsenoside Rh2 through improved understanding of its absorption and efflux mechanisms. | 2011 Oct |
2 |
| 235 |
21763326 | Expressions of multidrug resistance protein 1 and multidrug resistance-associated protein 1 in lung dendritic cells. | 2011 Aug 15 |
1 |
| 236 |
21804948 | Gemcitabine Cytotoxicity: Interaction of Efflux and Deamination. | 2011 Feb 2 |
1 |
| 237 |
21903258 | Synergistic effect of folate-mediated targeting and verapamil-mediated P-gp inhibition with paclitaxel -polymer micelles to overcome multi-drug resistance. | 2011 Dec |
3 |
| 238 |
19631272 | Xenopus laevis oocytes expressing human P-glycoprotein: probing trans- and cis-inhibitory effects on [3H]vinblastine and [3H]digoxin efflux. | 2010 Jan |
2 |
| 239 |
19726755 | Modulation of a Schistosoma mansoni multidrug transporter by the antischistosomal drug praziquantel. | 2010 Jan |
1 |
| 240 |
19914261 | Interaction of angiotensin II type 1 receptor blockers with P-gp substrates in Caco-2 cells and hMDR1-expressing membranes. | 2010 Jan 2 |
2 |
| 241 |
19944135 | L-type calcium channel blockers reverse docetaxel and vincristine-induced multidrug resistance independent of ABCB1 expression in human lung cancer cell lines. | 2010 Feb 15 |
2 |
| 242 |
19947891 | Clinical pharmacokinetics of fexofenadine enantiomers. | 2010 Jan |
2 |
| 243 |
19949935 | Immunosuppressors as multidrug resistance reversal agents. | 2010 |
2 |
| 244 |
20010957 | Assessment of regional differences in tariquidar-induced P-glycoprotein modulation at the human blood-brain barrier. | 2010 Mar |
1 |
| 245 |
20012601 | Pharmacokinetic interaction between oral lovastatin and verapamil in healthy subjects: role of P-glycoprotein inhibition by lovastatin. | 2010 Mar |
2 |
| 246 |
20069466 | No inhibitory effect on P-glycoprotein function at blood-brain barrier by clinical dose of clarithromycin: a human PET study with [¹¹C]verapamil. | 2010 Feb |
2 |
| 247 |
20071452 | High-activity p-glycoprotein, multidrug resistance protein 2, and breast cancer resistance protein membrane vesicles prepared from transiently transfected human embryonic kidney 293-epstein-barr virus nuclear antigen cells. | 2010 Apr |
1 |
| 248 |
20121715 | Induction of apoptosis by A3 adenosine receptor agonist N-(3-iodobenzyl)-adenosine-5'-N-methylcarboxamide in human leukaemia cells: a possible involvement of intracellular mechanism. | 2010 Jun |
2 |
| 249 |
20135207 | Model analysis of the concentration-dependent permeability of P-gp substrates. | 2010 Mar |
4 |
| 250 |
20336065 | Regional P-glycoprotein activity and inhibition at the human blood-brain barrier as imaged by positron emission tomography. | 2010 May |
1 |