Verapamil

ATP binding cassette subfamily B member 1 ; Homo sapiens







718 Article(s)
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201 22405646 Synthesis and biological evaluation of novel bifendate derivatives bearing 6,7-dihydro-dibenzo[c,e]azepine scaffold as potent P-glycoprotein inhibitors. 2012 May 1
202 22411726 Intestinal transport of pure diester-type alkaloids from an aconite extract across the Caco-2 cell monolayer model. 2012 May 1
203 22545578 Up-regulation of P-glycoprotein is involved in the increased paclitaxel resistance in human esophageal cancer radioresistant cells. 2012 Jul 1
204 22584255 Inhibition of P-glycoprotein leads to improved oral bioavailability of compound K, an anticancer metabolite of red ginseng extract produced by gut microflora. 2012 Aug 2
205 22588188 No evidence for additional blood-brain barrier P-glycoprotein dysfunction in Alzheimer's disease patients with microbleeds. 2012 Aug 2
206 22734651 Development of peptide-based reversing agents for p-glycoprotein-mediated resistance to carfilzomib. 2012 Aug 6 1
207 22764578 Blood-brain barrier in vitro models as tools in drug discovery: assessment of the transport ranking of antihistaminic drugs. 2012 May 3
208 22792804 [Effect of Shaoyao Gancao Tang on function and expression of P-glycoprotein in Caco-2 cells]. 2012 Apr 4
209 23046348 BBA, a derivative of 23-hydroxybetulinic acid, potently reverses ABCB1-mediated drug resistance in vitro and in vivo. 2012 Nov 5 1
210 23072916 Intestinal permeability of lamivudine (3TC) and two novel 3TC prodrugs. Experimental and theoretical analyses. 2012 Dec 18 2
211 23134497 P-glycoprotein imaging in temporal lobe epilepsy: in vivo PET experiments with the Pgp substrate [11C]-verapamil. 2012 Nov 3
212 23519262 Absorption and interaction of the main constituents from the traditional Chinese drug pair Shaoyao-Gancao via a Caco-2 cell monolayer model. 2012 Dec 13 3
213 20563580 Effect of MDR modulators verapamil and promethazine on gene expression levels of MDR1 and MRP1 in doxorubicin-resistant MCF-7 cells. 2011 Apr 3
214 20824508 Assessing p-glycoprotein (Pgp) activity in vivo utilizing 68Ga-Schiff base complexes. 2011 Oct 3
215 21062675 Reversion of resistance to immunosuppressive agents in three patients with psoriatic arthritis by cyclosporine A: modulation of P-glycoprotein function. 2011 Jan 2
216 21128075 Over-expression of MDR1 in amrubicinol-resistant lung cancer cells. 2011 Sep 1
217 21229388 Influence of P-glycoprotein on embryotoxicity of the antifouling biocides to sea urchin (Strongylocentrotus intermedius). 2011 Mar 2
218 21289467 Upregulation of P-glycoprotein activity in porcine oocytes and granulosa cells during in vitro maturation. 2011 Jun 2
219 21308736 Euphorbia factor L1 reverses ABCB1-mediated multidrug resistance involving interaction with ABCB1 independent of ABCB1 downregualtion. 2011 Apr 1
220 21336515 Assessment and modulation of phillyrin absorption by P-gp using Caco-2 cells and MDR1-MDCKII cells. 2011 Mar 1
221 21336967 P-glycoprotein enhances radiation-induced apoptotic cell death through the regulation of miR-16 and Bcl-2 expressions in hepatocellular carcinoma cells. 2011 May 3
222 21371443 A unique P-glycoprotein interacting agent displays anticancer activity against hepatocellular carcinoma through inhibition of GRP78 and mTOR pathways. 2011 May 1 2
223 21439263 On-line identification of P-glycoprotein substrates by monitoring of extracellular acidification and respiration rates in living cells. 2011 Jul 2
224 21440934 The mechanism of enhancement on oral absorption of paclitaxel by N-octyl-O-sulfate chitosan micelles. 2011 Jul 1
225 21491921 Liposome-encapsulated doxorubicin reverses drug resistance by inhibiting P-glycoprotein in human cancer cells. 2011 Jun 6 1
226 21538216 Resistance to the translation initiation inhibitor silvestrol is mediated by ABCB1/P-glycoprotein overexpression in acute lymphoblastic leukemia cells. 2011 Sep 1
227 21589945 Exhaustive sampling of docking poses reveals binding hypotheses for propafenone type inhibitors of P-glycoprotein. 2011 May 1
228 21634011 Identification of xanthones as selective killers of cancer cells overexpressing the ABC transporter MRP1. 2011 Aug 1 1
229 21636258 Regulation of endocytosis into human brain-microvascular endothelial cells by inhibition of efflux proteins. 2011 Oct 1 2
230 21692796 In vitro transport profile of carbamazepine, oxcarbazepine, eslicarbazepine acetate, and their active metabolites by human P-glycoprotein. 2011 Oct 1
231 21716273 Nonlinear pharmacokinetics of oral quinidine and verapamil in healthy subjects: a clinical microdosing study. 2011 Aug 2
232 21721007 Poor oral bioavailability of a promising anticancer agent andrographolide is due to extensive metabolism and efflux by P-glycoprotein. 2011 Nov 2
233 21733412 Exposure of LS-180 cells to drugs of diverse physicochemical and therapeutic properties up-regulates P-glycoprotein expression and activity. 2011 1
234 21757611 Enhancement of oral bioavailability of 20(S)-ginsenoside Rh2 through improved understanding of its absorption and efflux mechanisms. 2011 Oct 2
235 21763326 Expressions of multidrug resistance protein 1 and multidrug resistance-associated protein 1 in lung dendritic cells. 2011 Aug 15 1
236 21804948 Gemcitabine Cytotoxicity: Interaction of Efflux and Deamination. 2011 Feb 2 1
237 21903258 Synergistic effect of folate-mediated targeting and verapamil-mediated P-gp inhibition with paclitaxel -polymer micelles to overcome multi-drug resistance. 2011 Dec 3
238 19631272 Xenopus laevis oocytes expressing human P-glycoprotein: probing trans- and cis-inhibitory effects on [3H]vinblastine and [3H]digoxin efflux. 2010 Jan 2
239 19726755 Modulation of a Schistosoma mansoni multidrug transporter by the antischistosomal drug praziquantel. 2010 Jan 1
240 19914261 Interaction of angiotensin II type 1 receptor blockers with P-gp substrates in Caco-2 cells and hMDR1-expressing membranes. 2010 Jan 2 2
241 19944135 L-type calcium channel blockers reverse docetaxel and vincristine-induced multidrug resistance independent of ABCB1 expression in human lung cancer cell lines. 2010 Feb 15 2
242 19947891 Clinical pharmacokinetics of fexofenadine enantiomers. 2010 Jan 2
243 19949935 Immunosuppressors as multidrug resistance reversal agents. 2010 2
244 20010957 Assessment of regional differences in tariquidar-induced P-glycoprotein modulation at the human blood-brain barrier. 2010 Mar 1
245 20012601 Pharmacokinetic interaction between oral lovastatin and verapamil in healthy subjects: role of P-glycoprotein inhibition by lovastatin. 2010 Mar 2
246 20069466 No inhibitory effect on P-glycoprotein function at blood-brain barrier by clinical dose of clarithromycin: a human PET study with [¹¹C]verapamil. 2010 Feb 2
247 20071452 High-activity p-glycoprotein, multidrug resistance protein 2, and breast cancer resistance protein membrane vesicles prepared from transiently transfected human embryonic kidney 293-epstein-barr virus nuclear antigen cells. 2010 Apr 1
248 20121715 Induction of apoptosis by A3 adenosine receptor agonist N-(3-iodobenzyl)-adenosine-5'-N-methylcarboxamide in human leukaemia cells: a possible involvement of intracellular mechanism. 2010 Jun 2
249 20135207 Model analysis of the concentration-dependent permeability of P-gp substrates. 2010 Mar 4
250 20336065 Regional P-glycoprotein activity and inhibition at the human blood-brain barrier as imaged by positron emission tomography. 2010 May 1