Methotrexate

ATP binding cassette subfamily B member 1 ; Homo sapiens







75 Article(s)
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51 19915943 Etanercept overcomes P-glycoprotein-induced drug resistance in lymphocytes of patients with intractable rheumatoid arthritis. 2010 Apr 3
52 20136356 Functional polymorphisms and methotrexate treatment outcome in recent-onset rheumatoid arthritis. 2010 Feb 1
53 20533531 In vivo expansion of MDR1-transduced cells accompanied by a post-transplantation chemotherapy regimen with mitomycin C and methotrexate. 2010 Jul 2
54 17660216 Overcoming drug resistance induced by P-glycoprotein on lymphocytes in patients with refractory rheumatoid arthritis. 2008 Mar 1
55 18336795 Role of proline 1150 in functional interactions between the membrane spanning domains and nucleotide binding domains of the MRP1 (ABCC1) transporter. 2008 Apr 15 1
56 17982279 Cobalamin potentiates vinblastine cytotoxicity through downregulation of mdr-1 gene expression in HepG2 cells. 2007 1
57 16504991 Down regulation of multidrug resistance protein-1 expression in patients with early rheumatoid arthritis exposed to methotrexate as a first disease-modifying antirheumatic drug. 2006 Oct 12
58 16932953 The effect of 3435C>T MDR1 gene polymorphism on rheumatoid arthritis treatment with disease-modifying antirheumatic drugs. 2006 Nov 1
59 17181924 ABCB1 C3435T polymorphism influences methotrexate sensitivity in rheumatoid arthritis patients. 2006 Sep-Oct 2
60 15703814 Y-box binding protein, YB-1, as a marker of tumor aggressiveness and response to adjuvant chemotherapy in breast cancer. 2005 Mar 1
61 16259774 Involvement of P-glycoprotein in the release of cytokines from peripheral blood mononuclear cells treated with methotrexate and dexamethasone. 2005 Nov 2
62 16321374 Involvement of C3435T and G2677T multidrug resistance gene polymorphisms in release of cytokines from peripheral blood mononuclear cells treated with methotrexate and dexamethasone. 2005 Dec 28 2
63 15110230 P-glycoprotein in autoimmune diseases. 2004 Mar 1
64 12687290 Ketotifen reverses MDR1-mediated multidrug resistance in human breast cancer cells in vitro and alleviates cardiotoxicity induced by doxorubicin in vivo. 2003 May 1
65 12466237 The use of Tris-lipidation to modify drug cytotoxicity in multidrug resistant cells expressing P-glycoprotein or MRP1. 2002 Dec 1
66 11721885 Identification of human multidrug resistance protein 1 (MRP1) mutations and characterization of a G671V substitution. 2001 2
67 10664539 Caco-2 versus Caco-2/HT29-MTX co-cultured cell lines: permeabilities via diffusion, inside- and outside-directed carrier-mediated transport. 2000 Jan 3
68 10902777 Increased MDR1 P-glycoprotein expression in methotrexate resistance: comment on the article by Yudoh et al. 2000 Jul 2
69 10075817 A continuous fluorescence assay for the study of P-glycoprotein-mediated drug efflux using inside-out membrane vesicles. 1999 Mar 15 1
70 10430334 A case of colon cancer recurrence with P-glycoprotein treated by methotrexate, fluorouracil, and leucovorin. 1999 May-Jun 1
71 9754649 P-glycoprotein-mediated methotrexate resistance in CCRF-CEM sublines deficient in methotrexate accumulation due to a point mutation in the reduced folate carrier gene. 1998 Oct 5 12
72 8598312 Involvement of MDR1 P-glycoprotein in multifactorial resistance to methotrexate. 1996 Mar 1 4
73 8911123 Inhibition of Pgp activity and cell cycle-dependent chemosensitivity to doxorubicin in the multidrug-resistant LoVo human colon cancer cell line. 1996 Aug 1
74 7848886 P-glycoprotein expression in primary and metastatic transitional cell carcinoma of the bladder. 1994 Nov 1
75 7912069 P-glycoprotein overexpression in methotrexate-resistant Leishmania tropica. 1994 Jun 1 1