Phenylalanine

ATP binding cassette subfamily B member 1 ; Homo sapiens







15 Article(s)
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Pub. Year
#Total Relationships
1 32695413 Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein. 2020 Jul 1 1
2 28728917 Global alteration of the drug-binding pocket of human P-glycoprotein (ABCB1) by substitution of fifteen conserved residues reveals a negative correlation between substrate size and transport efficiency. 2017 Nov 1 1
3 27566564 Altered pH gradient at the plasma membrane of osteosarcoma cells is a key mechanism of drug resistance. 2016 Sep 27 2
4 22888853 The flexibility of P-glycoprotein for its poly-specific drug binding from molecular dynamics simulations. 2013 1
5 23104431 Interaction of digitalis-like compounds with p-glycoprotein. 2013 Feb 4
6 22439003 Prediction of promiscuous p-glycoprotein inhibition using a novel machine learning scheme. 2012 2
7 15542593 The dileucine motif at the COOH terminus of human multidrug resistance P-glycoprotein is important for folding but not activity. 2005 Jan 28 2
8 15247215 Processing mutations located throughout the human multidrug resistance P-glycoprotein disrupt interactions between the nucleotide binding domains. 2004 Sep 10 1
9 15292579 $3,3',4,4',5$ -Pentachlorobiphenyl Inhibits Drug Efflux Through P-Glycoprotein in KB-3 Cells Expressing Mutant Human P-Glycoprotein. 2004 1
10 12070134 Introduction of the most common cystic fibrosis mutation (Delta F508) into human P-glycoprotein disrupts packing of the transmembrane segments. 2002 Aug 2 1
11 11328489 Transport characteristics of peptides and peptidomimetics: I. N-methylated peptides as substrates for the oligopeptide transporter and P-glycoprotein in the intestinal mucosa. 2001 Apr 2
12 10727524 Loss of cyclosporin and azidopine binding are associated with altered ATPase activity by a mutant P-glycoprotein with deleted phe(335). 2000 Apr 5
13 9038218 Multidrug-resistant human sarcoma cells with a mutant P-glycoprotein, altered phenotype, and resistance to cyclosporins. 1997 Feb 28 1
14 7904655 Transmembrane aromatic amino acid distribution in P-glycoprotein. A functional role in broad substrate specificity. 1994 Jan 14 1
15 8104183 Functional consequences of phenylalanine mutations in the predicted transmembrane domain of P-glycoprotein. 1993 Sep 25 4